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Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes.
J Am Chem Soc. 2008 Dec 24; 130(51):17232-3.JA

Abstract

A rhodium(I) catalyst incorporating the Me-DuPhos ligand promotes enantioselective intermolecular hydroacylation between beta-S-aldehydes and 1,3-disubstituted allenes. The nonconjugated enone products are obtained in good yields and with high enantioselectivities.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Osborne JD
Department of Chemistry, University of Oxford, Chemical Research Laboratory, Mansfield Road, Oxford, UK.
Randell-Sly HE
No affiliation info available
Currie GS
No affiliation info available
Cowley AR
No affiliation info available
Willis MC
No affiliation info available

MeSH

AldehydesAlkenesCarbonCatalysisChemistryLigandsMetalsModels, ChemicalMolecular StructureRhodiumStereoisomerismTemperature

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19053453

Citation

Osborne, James D., et al. "Catalytic Enantioselective Intermolecular Hydroacylation: Rhodium-catalyzed Combination of beta-S-aldehydes and 1,3-disubstituted Allenes." Journal of the American Chemical Society, vol. 130, no. 51, 2008, pp. 17232-3.
Osborne JD, Randell-Sly HE, Currie GS, et al. Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes. J Am Chem Soc. 2008;130(51):17232-3.
Osborne, J. D., Randell-Sly, H. E., Currie, G. S., Cowley, A. R., & Willis, M. C. (2008). Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes. Journal of the American Chemical Society, 130(51), 17232-3. https://doi.org/10.1021/ja8069133
Osborne JD, et al. Catalytic Enantioselective Intermolecular Hydroacylation: Rhodium-catalyzed Combination of beta-S-aldehydes and 1,3-disubstituted Allenes. J Am Chem Soc. 2008 Dec 24;130(51):17232-3. PubMed PMID: 19053453.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Catalytic enantioselective intermolecular hydroacylation: rhodium-catalyzed combination of beta-S-aldehydes and 1,3-disubstituted allenes. AU - Osborne,James D, AU - Randell-Sly,Helen E, AU - Currie,Gordon S, AU - Cowley,Andrew R, AU - Willis,Michael C, PY - 2008/12/5/pubmed PY - 2009/8/6/medline PY - 2008/12/5/entrez SP - 17232 EP - 3 JF - Journal of the American Chemical Society JO - J Am Chem Soc VL - 130 IS - 51 N2 - A rhodium(I) catalyst incorporating the Me-DuPhos ligand promotes enantioselective intermolecular hydroacylation between beta-S-aldehydes and 1,3-disubstituted allenes. The nonconjugated enone products are obtained in good yields and with high enantioselectivities. SN - 1520-5126 UR - https://www.unboundmedicine.com/medline/citation/19053453/Catalytic_enantioselective_intermolecular_hydroacylation:_rhodium_catalyzed_combination_of_beta_S_aldehydes_and_13_disubstituted_allenes_ L2 - https://doi.org/10.1021/ja8069133 DB - PRIME DP - Unbound Medicine ER -