Tags

Type your tag names separated by a space and hit enter

Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal.
Am J Ophthalmol. 2009 Mar; 147(3):473-480.e3.AJ

Abstract

PURPOSE

To identify characteristics measured by optical coherence tomography (OCT) that are correlated with visual outcome after epiretinal membrane (ERM) removal by pars plana vitrectomy (PPV).

DESIGN

Interventional, prospective, randomized case series.

METHODS

One hundred and one eyes of 101 patients with idiopathic ERM underwent PPV for ERM removal. Ophthalmic evaluations included best-corrected visual acuity (BCVA) and Stratus OCT preoperatively at 3 and 6 months postoperatively. Relations between three OCT features including integrity of junction between inner and outer segments of photoreceptors (IS/OS junction), macular thickness, foveal contour and the three visual acuity parameters such as preoperative BCVAs, postoperative BCVAs, and the differences between preoperative and postoperative BCVAs (BCVA differences) were evaluated with respect to time.

RESULTS

Eyes with disruption of IS/OS junction had significantly lower postoperative BCVA and BCVA differences than those without disruption (P < .0001, respectively). "Same" (increment or decrement of BCVA up to 1 Snellen line) and "Better" (visual increment of at least 2 Snellen lines) BCVA outcome groups were significantly different with respect to the status of IS/OS junction (P < .005). An increase in the proportion of eyes with photoreceptor disruption was observed at 3 months postoperatively, and this proportion was maintained afterward. Preoperative macular thicknesses showed a positive correlation with BCVA differences, and postoperative macular thicknesses negatively correlated with postoperative BCVA (r > 0.25; P < .05, respectively). Thickness difference and foveal contour were not correlated with the three parameters of visual outcome (P > .05, respectively).

CONCLUSION

Photoreceptor disruption detected by OCT was found to be a predictor of poor visual outcome in eyes with idiopathic ERM, and it was found that this disruption may be irreversible. Thus, early membrane removals may beneficially prevent further progression of photoreceptor damage in ERM patients with photoreceptor disruption.

Authors+Show Affiliations

Department of Ophthalmology, Seoul National University College of Medicine, Korea.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

19054492

Citation

Suh, Min Hee, et al. "Associations Between Macular Findings By Optical Coherence Tomography and Visual Outcomes After Epiretinal Membrane Removal." American Journal of Ophthalmology, vol. 147, no. 3, 2009, pp. 473-480.e3.
Suh MH, Seo JM, Park KH, et al. Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal. Am J Ophthalmol. 2009;147(3):473-480.e3.
Suh, M. H., Seo, J. M., Park, K. H., & Yu, H. G. (2009). Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal. American Journal of Ophthalmology, 147(3), 473-e3. https://doi.org/10.1016/j.ajo.2008.09.020
Suh MH, et al. Associations Between Macular Findings By Optical Coherence Tomography and Visual Outcomes After Epiretinal Membrane Removal. Am J Ophthalmol. 2009;147(3):473-480.e3. PubMed PMID: 19054492.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Associations between macular findings by optical coherence tomography and visual outcomes after epiretinal membrane removal. AU - Suh,Min Hee, AU - Seo,Jong Mo, AU - Park,Kyu Hyung, AU - Yu,Hyeong Gon, Y1 - 2008/12/03/ PY - 2008/02/04/received PY - 2008/09/11/revised PY - 2008/09/12/accepted PY - 2008/12/5/pubmed PY - 2009/2/27/medline PY - 2008/12/5/entrez SP - 473 EP - 480.e3 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 147 IS - 3 N2 - PURPOSE: To identify characteristics measured by optical coherence tomography (OCT) that are correlated with visual outcome after epiretinal membrane (ERM) removal by pars plana vitrectomy (PPV). DESIGN: Interventional, prospective, randomized case series. METHODS: One hundred and one eyes of 101 patients with idiopathic ERM underwent PPV for ERM removal. Ophthalmic evaluations included best-corrected visual acuity (BCVA) and Stratus OCT preoperatively at 3 and 6 months postoperatively. Relations between three OCT features including integrity of junction between inner and outer segments of photoreceptors (IS/OS junction), macular thickness, foveal contour and the three visual acuity parameters such as preoperative BCVAs, postoperative BCVAs, and the differences between preoperative and postoperative BCVAs (BCVA differences) were evaluated with respect to time. RESULTS: Eyes with disruption of IS/OS junction had significantly lower postoperative BCVA and BCVA differences than those without disruption (P < .0001, respectively). "Same" (increment or decrement of BCVA up to 1 Snellen line) and "Better" (visual increment of at least 2 Snellen lines) BCVA outcome groups were significantly different with respect to the status of IS/OS junction (P < .005). An increase in the proportion of eyes with photoreceptor disruption was observed at 3 months postoperatively, and this proportion was maintained afterward. Preoperative macular thicknesses showed a positive correlation with BCVA differences, and postoperative macular thicknesses negatively correlated with postoperative BCVA (r > 0.25; P < .05, respectively). Thickness difference and foveal contour were not correlated with the three parameters of visual outcome (P > .05, respectively). CONCLUSION: Photoreceptor disruption detected by OCT was found to be a predictor of poor visual outcome in eyes with idiopathic ERM, and it was found that this disruption may be irreversible. Thus, early membrane removals may beneficially prevent further progression of photoreceptor damage in ERM patients with photoreceptor disruption. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/19054492/Associations_between_macular_findings_by_optical_coherence_tomography_and_visual_outcomes_after_epiretinal_membrane_removal_ DB - PRIME DP - Unbound Medicine ER -