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Serum lipid and apolipoprotein concentrations in healthy men on diets enriched in either canola oil or safflower oil.
Am J Clin Nutr. 1991 Jul; 54(1):104-10.AJ

Abstract

This randomized, blind study measured changes in serum lipid and apolipoprotein concentrations in 16 men consuming 39 +/- 1% of energy (en%) as fat either from safflower- or canola-oil-based diets for 8 wk. Initially, the men were stabilized for 3 wk on a typical American (baseline) diet. Compared with baseline, the vegetable-oil-based diets reduced serum total cholesterol 9-15% (P less than 0.002), low-density-lipoprotein (LDL)-cholesterol 12-20% (P less than 0.002), and apolipoprotein B-100 21-24% (P less than 0.001). There were no significant changes from baseline to the end of the study in serum triglycerides, total high-density-lipoprotein (HDL) cholesterol, HDL3 cholesterol, HDL2 cholesterol, or apolipoprotein A-I. These data suggest that even if total fat intake remains at 39-40 en%, many men show lowered LDL cholesterol if saturated fatty acid intake is minimized and that diets high in polyunsaturated fatty acids do not necessarily lower HDL-cholesterol concentrations.

Authors+Show Affiliations

Division of Medical Dietetics, Ohio State University, Columbus 43210.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1905474

Citation

Wardlaw, G M., et al. "Serum Lipid and Apolipoprotein Concentrations in Healthy Men On Diets Enriched in Either Canola Oil or Safflower Oil." The American Journal of Clinical Nutrition, vol. 54, no. 1, 1991, pp. 104-10.
Wardlaw GM, Snook JT, Lin MC, et al. Serum lipid and apolipoprotein concentrations in healthy men on diets enriched in either canola oil or safflower oil. Am J Clin Nutr. 1991;54(1):104-10.
Wardlaw, G. M., Snook, J. T., Lin, M. C., Puangco, M. A., & Kwon, J. S. (1991). Serum lipid and apolipoprotein concentrations in healthy men on diets enriched in either canola oil or safflower oil. The American Journal of Clinical Nutrition, 54(1), 104-10.
Wardlaw GM, et al. Serum Lipid and Apolipoprotein Concentrations in Healthy Men On Diets Enriched in Either Canola Oil or Safflower Oil. Am J Clin Nutr. 1991;54(1):104-10. PubMed PMID: 1905474.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum lipid and apolipoprotein concentrations in healthy men on diets enriched in either canola oil or safflower oil. AU - Wardlaw,G M, AU - Snook,J T, AU - Lin,M C, AU - Puangco,M A, AU - Kwon,J S, PY - 1991/7/1/pubmed PY - 1991/7/1/medline PY - 1991/7/1/entrez SP - 104 EP - 10 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 54 IS - 1 N2 - This randomized, blind study measured changes in serum lipid and apolipoprotein concentrations in 16 men consuming 39 +/- 1% of energy (en%) as fat either from safflower- or canola-oil-based diets for 8 wk. Initially, the men were stabilized for 3 wk on a typical American (baseline) diet. Compared with baseline, the vegetable-oil-based diets reduced serum total cholesterol 9-15% (P less than 0.002), low-density-lipoprotein (LDL)-cholesterol 12-20% (P less than 0.002), and apolipoprotein B-100 21-24% (P less than 0.001). There were no significant changes from baseline to the end of the study in serum triglycerides, total high-density-lipoprotein (HDL) cholesterol, HDL3 cholesterol, HDL2 cholesterol, or apolipoprotein A-I. These data suggest that even if total fat intake remains at 39-40 en%, many men show lowered LDL cholesterol if saturated fatty acid intake is minimized and that diets high in polyunsaturated fatty acids do not necessarily lower HDL-cholesterol concentrations. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/1905474/Serum_lipid_and_apolipoprotein_concentrations_in_healthy_men_on_diets_enriched_in_either_canola_oil_or_safflower_oil_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/54.1.104 DB - PRIME DP - Unbound Medicine ER -