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Predicted contribution of folic acid fortification of corn masa flour to the usual folic acid intake for the US population: National Health and Nutrition Examination Survey 2001-2004.
Am J Clin Nutr. 2009 Jan; 89(1):305-15.AJ

Abstract

BACKGROUND

Folic acid can prevent up to 70% of neural tube defects (NTDs) if taken before pregnancy. Compared with other race-ethnicities, Hispanic women have higher rates of NTDs, lower rates of folic acid supplement use, and lower total folic acid intakes.

OBJECTIVE

The objective was to assess potential effects of fortifying corn masa flour with folic acid on Mexican American women and other segments of the US population.

DESIGN

A model was developed by using data from the National Health and Nutrition Examination Survey 2001-2004 to estimate the folic acid content in foods containing corn masa flour if fortified at a level of 140 microg folic acid/100 g corn masa flour.

RESULTS

Had corn masa flour fortification occurred, we estimated that Mexican American women aged 15-44 y could have increased their total usual daily folic acid intake by 19.9% and non-Hispanic white women by 4.2%. Among the US population, estimated relative percentage increases in total usual daily folic acid intake with corn masa flour fortification were greatest among Mexican Americans (16.8%) and lowest among children aged 1-3 y (2%) and adults aged >51 y (0-0.5%).

CONCLUSION

Analyses suggest that corn masa flour fortification would have effectively targeted Mexican Americans, specifically, Mexican American women, without substantially increasing folic acid intake among other segments of the population. Such increases could reduce the disparity in total folic acid intake between Mexican American and non-Hispanic white women of childbearing age and implies that an additional NTD preventive benefit would be observed for Mexican American women.

Authors+Show Affiliations

Division of Birth Defects and Developmental Disabilities, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. hfc2@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19056605

Citation

Hamner, Heather C., et al. "Predicted Contribution of Folic Acid Fortification of Corn Masa Flour to the Usual Folic Acid Intake for the US Population: National Health and Nutrition Examination Survey 2001-2004." The American Journal of Clinical Nutrition, vol. 89, no. 1, 2009, pp. 305-15.
Hamner HC, Mulinare J, Cogswell ME, et al. Predicted contribution of folic acid fortification of corn masa flour to the usual folic acid intake for the US population: National Health and Nutrition Examination Survey 2001-2004. Am J Clin Nutr. 2009;89(1):305-15.
Hamner, H. C., Mulinare, J., Cogswell, M. E., Flores, A. L., Boyle, C. A., Prue, C. E., Wang, C. Y., Carriquiry, A. L., & Devine, O. (2009). Predicted contribution of folic acid fortification of corn masa flour to the usual folic acid intake for the US population: National Health and Nutrition Examination Survey 2001-2004. The American Journal of Clinical Nutrition, 89(1), 305-15. https://doi.org/10.3945/ajcn.2008.26331
Hamner HC, et al. Predicted Contribution of Folic Acid Fortification of Corn Masa Flour to the Usual Folic Acid Intake for the US Population: National Health and Nutrition Examination Survey 2001-2004. Am J Clin Nutr. 2009;89(1):305-15. PubMed PMID: 19056605.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Predicted contribution of folic acid fortification of corn masa flour to the usual folic acid intake for the US population: National Health and Nutrition Examination Survey 2001-2004. AU - Hamner,Heather C, AU - Mulinare,Joseph, AU - Cogswell,Mary E, AU - Flores,Alina L, AU - Boyle,Coleen A, AU - Prue,Christine E, AU - Wang,Chia-Yih, AU - Carriquiry,Alicia L, AU - Devine,Owen, Y1 - 2008/12/03/ PY - 2008/12/6/pubmed PY - 2009/2/6/medline PY - 2008/12/6/entrez SP - 305 EP - 15 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 89 IS - 1 N2 - BACKGROUND: Folic acid can prevent up to 70% of neural tube defects (NTDs) if taken before pregnancy. Compared with other race-ethnicities, Hispanic women have higher rates of NTDs, lower rates of folic acid supplement use, and lower total folic acid intakes. OBJECTIVE: The objective was to assess potential effects of fortifying corn masa flour with folic acid on Mexican American women and other segments of the US population. DESIGN: A model was developed by using data from the National Health and Nutrition Examination Survey 2001-2004 to estimate the folic acid content in foods containing corn masa flour if fortified at a level of 140 microg folic acid/100 g corn masa flour. RESULTS: Had corn masa flour fortification occurred, we estimated that Mexican American women aged 15-44 y could have increased their total usual daily folic acid intake by 19.9% and non-Hispanic white women by 4.2%. Among the US population, estimated relative percentage increases in total usual daily folic acid intake with corn masa flour fortification were greatest among Mexican Americans (16.8%) and lowest among children aged 1-3 y (2%) and adults aged >51 y (0-0.5%). CONCLUSION: Analyses suggest that corn masa flour fortification would have effectively targeted Mexican Americans, specifically, Mexican American women, without substantially increasing folic acid intake among other segments of the population. Such increases could reduce the disparity in total folic acid intake between Mexican American and non-Hispanic white women of childbearing age and implies that an additional NTD preventive benefit would be observed for Mexican American women. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/19056605/Predicted_contribution_of_folic_acid_fortification_of_corn_masa_flour_to_the_usual_folic_acid_intake_for_the_US_population:_National_Health_and_Nutrition_Examination_Survey_2001_2004_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.3945/ajcn.2008.26331 DB - PRIME DP - Unbound Medicine ER -