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Modified citrus pectin anti-metastatic properties: one bullet, multiple targets.
Carbohydr Res. 2009 Sep 28; 344(14):1788-91.CR

Abstract

In this minireview, we examine the ability of modified citrus pectin (MCP), a complex water soluble indigestible polysaccharide obtained from the peel and pulp of citrus fruits and modified by means of high pH and temperature treatment, to affect numerous rate-limiting steps in cancer metastasis. The anti-adhesive properties of MCP as well as its potential for increasing apoptotic responses of tumor cells to chemotherapy by inhibiting galectin-3 anti-apoptotic function are discussed in the light of a potential use of this carbohydrate-based substance in the treatment of multiple human malignancies.

Authors+Show Affiliations

Harry S. Truman Memorial Veterans' Hospital, Columbia, MO 65201, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19061992

Citation

Glinsky, Vladislav V., and Avraham Raz. "Modified Citrus Pectin Anti-metastatic Properties: One Bullet, Multiple Targets." Carbohydrate Research, vol. 344, no. 14, 2009, pp. 1788-91.
Glinsky VV, Raz A. Modified citrus pectin anti-metastatic properties: one bullet, multiple targets. Carbohydr Res. 2009;344(14):1788-91.
Glinsky, V. V., & Raz, A. (2009). Modified citrus pectin anti-metastatic properties: one bullet, multiple targets. Carbohydrate Research, 344(14), 1788-91. https://doi.org/10.1016/j.carres.2008.08.038
Glinsky VV, Raz A. Modified Citrus Pectin Anti-metastatic Properties: One Bullet, Multiple Targets. Carbohydr Res. 2009 Sep 28;344(14):1788-91. PubMed PMID: 19061992.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Modified citrus pectin anti-metastatic properties: one bullet, multiple targets. AU - Glinsky,Vladislav V, AU - Raz,Avraham, Y1 - 2008/09/26/ PY - 2008/07/31/received PY - 2008/08/19/accepted PY - 2008/12/9/pubmed PY - 2009/12/18/medline PY - 2008/12/9/entrez SP - 1788 EP - 91 JF - Carbohydrate research JO - Carbohydr Res VL - 344 IS - 14 N2 - In this minireview, we examine the ability of modified citrus pectin (MCP), a complex water soluble indigestible polysaccharide obtained from the peel and pulp of citrus fruits and modified by means of high pH and temperature treatment, to affect numerous rate-limiting steps in cancer metastasis. The anti-adhesive properties of MCP as well as its potential for increasing apoptotic responses of tumor cells to chemotherapy by inhibiting galectin-3 anti-apoptotic function are discussed in the light of a potential use of this carbohydrate-based substance in the treatment of multiple human malignancies. SN - 1873-426X UR - https://www.unboundmedicine.com/medline/citation/19061992/Modified_citrus_pectin_anti_metastatic_properties:_one_bullet_multiple_targets_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0008-6215(08)00410-2 DB - PRIME DP - Unbound Medicine ER -