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Cardiovascular risk is more related to drinking pattern than to the type of alcoholic drinks.
Neth J Med 2008; 66(11):467-73NJ

Abstract

Many observational studies have shown an association between moderate alcohol consumption and a lower risk for cardiovascular morbidity and mortality. Some of these studies, whether or not inspired by the French paradox, suggest a more favourable effect of wine than of other alcoholic drinks. Certain polyphenols including the flavonoids, more abundant in red than in white wine, are held responsible for this 'bonus' effect. However, this conclusion seems premature, since no significant bioactive effect of wine polyphenols has been shown in humans so far. Furthermore, wine drinking proves to be associated with a healthier lifestyle profile than consumption of beer and liquor, and this may have a substantial influence on the outcome of studies. In contrast to moderate drinking, incidental heavy or binge drinking is associated with an increased cardiovascular risk by influences both on the electrical conduction system of the heart and the process of atherothrombosis. Although only prospective randomised intervention trials including a sufficient number of people will give definite answers, the chances are small that they will ever be performed given the ethical and practical objections of such studies. Available data so far justify the conclusion with regard to cardiovascular risk that the pattern of drinking is of more importance than the content of the bottle.

Authors+Show Affiliations

Department of Internal Medicine, Meander Medical Centre, Amersfoort, the Netherlands. a.vande.wiel@meandermc.nlNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19075312

Citation

van de Wiel, A, and D W. de Lange. "Cardiovascular Risk Is More Related to Drinking Pattern Than to the Type of Alcoholic Drinks." The Netherlands Journal of Medicine, vol. 66, no. 11, 2008, pp. 467-73.
van de Wiel A, de Lange DW. Cardiovascular risk is more related to drinking pattern than to the type of alcoholic drinks. Neth J Med. 2008;66(11):467-73.
van de Wiel, A., & de Lange, D. W. (2008). Cardiovascular risk is more related to drinking pattern than to the type of alcoholic drinks. The Netherlands Journal of Medicine, 66(11), pp. 467-73.
van de Wiel A, de Lange DW. Cardiovascular Risk Is More Related to Drinking Pattern Than to the Type of Alcoholic Drinks. Neth J Med. 2008;66(11):467-73. PubMed PMID: 19075312.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiovascular risk is more related to drinking pattern than to the type of alcoholic drinks. AU - van de Wiel,A, AU - de Lange,D W, PY - 2008/12/17/entrez PY - 2008/12/17/pubmed PY - 2009/2/26/medline SP - 467 EP - 73 JF - The Netherlands journal of medicine JO - Neth J Med VL - 66 IS - 11 N2 - Many observational studies have shown an association between moderate alcohol consumption and a lower risk for cardiovascular morbidity and mortality. Some of these studies, whether or not inspired by the French paradox, suggest a more favourable effect of wine than of other alcoholic drinks. Certain polyphenols including the flavonoids, more abundant in red than in white wine, are held responsible for this 'bonus' effect. However, this conclusion seems premature, since no significant bioactive effect of wine polyphenols has been shown in humans so far. Furthermore, wine drinking proves to be associated with a healthier lifestyle profile than consumption of beer and liquor, and this may have a substantial influence on the outcome of studies. In contrast to moderate drinking, incidental heavy or binge drinking is associated with an increased cardiovascular risk by influences both on the electrical conduction system of the heart and the process of atherothrombosis. Although only prospective randomised intervention trials including a sufficient number of people will give definite answers, the chances are small that they will ever be performed given the ethical and practical objections of such studies. Available data so far justify the conclusion with regard to cardiovascular risk that the pattern of drinking is of more importance than the content of the bottle. SN - 0300-2977 UR - https://www.unboundmedicine.com/medline/citation/19075312/Cardiovascular_risk_is_more_related_to_drinking_pattern_than_to_the_type_of_alcoholic_drinks_ L2 - http://www.njmonline.nl/njm/getarticle.php?v=66&i=11&p=467 DB - PRIME DP - Unbound Medicine ER -