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Waist circumference predicts cardiovascular risk in young Australian children.
J Paediatr Child Health. 2008 Dec; 44(12):709-15.JP

Abstract

AIM

It has been shown that compared with healthyweight children, overweight and obese primary school-aged children have a higher incidence of hyperinsulinism, dyslipidaemia and hypertension. It is therefore important to investigate clinically relevant markers of cardiovascular risk in children. Waist circumference is a simple, non-invasive anthropometric measure, but its association with cardiovascular risk profile in young Australian children is not clear.

METHODS

This study presents cross-sectional data from the Growth and Development Study. The sample included 70 healthy weight children, 50 overweight children and 28 obese children (n = 148, 9.6 +/- 1.9 years). All children had a medical assessment which included a physical examination (waist circumference, blood pressure), and investigations including glycated haemoglobin, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, insulin, glucose and total homocysteine levels. An oral glucose tolerance test was performed in a subgroup of children (n = 119). Body mass index (BMI) was determined and BMI Z-scores calculated.

RESULTS

In a multilevel model, waist circumference was the only significant anthropometric predictor of lipid profile (high-density lipoprotein beta = -0.01, P < 0.05; triglycerides beta = 0.01, P < 0.005), systolic blood pressure (beta = 0.29, P < 0.05), fasting insulin (beta = 0.16, P < 0.005), insulin concentrations throughout the oral glucose tolerance (60 min beta = 1.07, P < 0.005; 120 min beta = 1.42, P < 0.001) and insulin resistance (homeostasis model assessment (HOMA-IR): beta = 0.03, P < 0.05), with increasing waist circumference associated with increasing cardiovascular risk. In contrast, BMI Z-score was only predictive of 120-min glucose concentrations during the OGTT (beta = 0.34, P < 0.05).

CONCLUSIONS

Waist circumference is a better anthropometric indicator than BMI Z-score of cardiovascular risk in Australian primary school-aged children. Even in young children, measurement of waist circumference represents a simple, non-invasive screening tool to identify children with an increased cardiovascular risk profile.

Authors+Show Affiliations

Telethon Institute for Child Health Research, Centre for Child Health Research, Centre for Child Health Research, Perth, Western Australia, Australia. katiew@ichr.uwa.edu.auNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19077071

Citation

Watts, Katie, et al. "Waist Circumference Predicts Cardiovascular Risk in Young Australian Children." Journal of Paediatrics and Child Health, vol. 44, no. 12, 2008, pp. 709-15.
Watts K, Bell LM, Byrne SM, et al. Waist circumference predicts cardiovascular risk in young Australian children. J Paediatr Child Health. 2008;44(12):709-15.
Watts, K., Bell, L. M., Byrne, S. M., Jones, T. W., & Davis, E. A. (2008). Waist circumference predicts cardiovascular risk in young Australian children. Journal of Paediatrics and Child Health, 44(12), 709-15. https://doi.org/10.1111/j.1440-1754.2008.01411.x
Watts K, et al. Waist Circumference Predicts Cardiovascular Risk in Young Australian Children. J Paediatr Child Health. 2008;44(12):709-15. PubMed PMID: 19077071.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Waist circumference predicts cardiovascular risk in young Australian children. AU - Watts,Katie, AU - Bell,Lana M, AU - Byrne,Susan M, AU - Jones,Timothy W, AU - Davis,Elizabeth A, Y1 - 2008/11/28/ PY - 2008/12/17/entrez PY - 2008/12/17/pubmed PY - 2009/5/27/medline SP - 709 EP - 15 JF - Journal of paediatrics and child health JO - J Paediatr Child Health VL - 44 IS - 12 N2 - AIM: It has been shown that compared with healthyweight children, overweight and obese primary school-aged children have a higher incidence of hyperinsulinism, dyslipidaemia and hypertension. It is therefore important to investigate clinically relevant markers of cardiovascular risk in children. Waist circumference is a simple, non-invasive anthropometric measure, but its association with cardiovascular risk profile in young Australian children is not clear. METHODS: This study presents cross-sectional data from the Growth and Development Study. The sample included 70 healthy weight children, 50 overweight children and 28 obese children (n = 148, 9.6 +/- 1.9 years). All children had a medical assessment which included a physical examination (waist circumference, blood pressure), and investigations including glycated haemoglobin, total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides, insulin, glucose and total homocysteine levels. An oral glucose tolerance test was performed in a subgroup of children (n = 119). Body mass index (BMI) was determined and BMI Z-scores calculated. RESULTS: In a multilevel model, waist circumference was the only significant anthropometric predictor of lipid profile (high-density lipoprotein beta = -0.01, P < 0.05; triglycerides beta = 0.01, P < 0.005), systolic blood pressure (beta = 0.29, P < 0.05), fasting insulin (beta = 0.16, P < 0.005), insulin concentrations throughout the oral glucose tolerance (60 min beta = 1.07, P < 0.005; 120 min beta = 1.42, P < 0.001) and insulin resistance (homeostasis model assessment (HOMA-IR): beta = 0.03, P < 0.05), with increasing waist circumference associated with increasing cardiovascular risk. In contrast, BMI Z-score was only predictive of 120-min glucose concentrations during the OGTT (beta = 0.34, P < 0.05). CONCLUSIONS: Waist circumference is a better anthropometric indicator than BMI Z-score of cardiovascular risk in Australian primary school-aged children. Even in young children, measurement of waist circumference represents a simple, non-invasive screening tool to identify children with an increased cardiovascular risk profile. SN - 1440-1754 UR - https://www.unboundmedicine.com/medline/citation/19077071/Waist_circumference_predicts_cardiovascular_risk_in_young_Australian_children_ L2 - https://doi.org/10.1111/j.1440-1754.2008.01411.x DB - PRIME DP - Unbound Medicine ER -