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Comorbidities in polycystic ovary syndrome: their relationship to insulin resistance.
Panminerva Med. 2008 Dec; 50(4):295-304.PM

Abstract

The polycystic ovary syndrome (PCOS) affects 5-10% of women of child-bearing age, and the diagnosis carries with it associated metabolic and cardiovascular risk factors that are likely linked to insulin resistance. Consequently, women affected by PCOS are at significant risk for developing type 2 diabetes mellitus, cardiovascular disease, and obstructive sleep apnea. Aggressive screening for glucose intolerance and cardiovascular risk factors should be performed in all PCOS patients, and, when indicated by symptomatology, affected women should be screened for sleep apnea. Long-term goals of therapy should focus on prevention of these comorbidities.

Authors+Show Affiliations

Bethea SW
Division of Endocrinology and Metabolism, Department of Internal Medicine, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA, USA. jnestler@mc vhvcu.edu
Nestler JE
No affiliation info available

MeSH

Cardiovascular DiseasesComorbidityDiabetes ComplicationsDyslipidemiasFemaleHumansInsulin ResistanceMetabolic SyndromePolycystic Ovary SyndromeRisk FactorsSleep Apnea, ObstructiveUnited States

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19078870

Citation

Bethea, S W., and J E. Nestler. "Comorbidities in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance." Panminerva Medica, vol. 50, no. 4, 2008, pp. 295-304.
Bethea SW, Nestler JE. Comorbidities in polycystic ovary syndrome: their relationship to insulin resistance. Panminerva Med. 2008;50(4):295-304.
Bethea, S. W., & Nestler, J. E. (2008). Comorbidities in polycystic ovary syndrome: their relationship to insulin resistance. Panminerva Medica, 50(4), 295-304.
Bethea SW, Nestler JE. Comorbidities in Polycystic Ovary Syndrome: Their Relationship to Insulin Resistance. Panminerva Med. 2008;50(4):295-304. PubMed PMID: 19078870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comorbidities in polycystic ovary syndrome: their relationship to insulin resistance. AU - Bethea,S W, AU - Nestler,J E, PY - 2008/12/17/entrez PY - 2008/12/17/pubmed PY - 2009/4/16/medline SP - 295 EP - 304 JF - Panminerva medica JO - Panminerva Med VL - 50 IS - 4 N2 - The polycystic ovary syndrome (PCOS) affects 5-10% of women of child-bearing age, and the diagnosis carries with it associated metabolic and cardiovascular risk factors that are likely linked to insulin resistance. Consequently, women affected by PCOS are at significant risk for developing type 2 diabetes mellitus, cardiovascular disease, and obstructive sleep apnea. Aggressive screening for glucose intolerance and cardiovascular risk factors should be performed in all PCOS patients, and, when indicated by symptomatology, affected women should be screened for sleep apnea. Long-term goals of therapy should focus on prevention of these comorbidities. SN - 0031-0808 UR - https://www.unboundmedicine.com/medline/citation/19078870/Comorbidities_in_polycystic_ovary_syndrome:_their_relationship_to_insulin_resistance_ L2 - https://medlineplus.gov/polycysticovarysyndrome.html DB - PRIME DP - Unbound Medicine ER -