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Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi'an city of Shaanxi Province.
Forensic Sci Int Genet. 2008 Mar; 2(2):e15-8.FS

Abstract

Fifteen autosomal STRs loci were analyzed from a population sample of 446 unrelated healthy individuals of Chinese Han population residing in Xi'an city of Shaanxi Province using a multiplex PCR system. We report allele frequencies distribution and statistical parameters for all STR loci, D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA. The observed genotype frequencies and expected of genotype frequencies were evaluated by chi(2)-test and the Fisher exact tests. Chi-Square test showed all STR loci were in Hardy-Weinberg equilibrium (p<0.05). Our studied population data were compared with the previously published population data of other ethnics or areas. After comparing, significant differences were found between Chinese Han population in Xi'an and Korean, Tibetan, Uigur, Chinese Han population in Guangdong Province, Hui population, Chinese Salar, Dongxiang and Tu ethnic minority living in Qinghai Province of China at some loci. The forensic parameters from the data showed high values. The data in the present study can be used greatly for routine forensic application in the region of Xi'an city.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Wu YM
Department of Pathophysiology, The Fmmu Center for DNA Typing, The Fourth Military Medical University, Shaanxi Province, China. wuym@fmmu.edu.cn
Zhang XN
No affiliation info available
Zhou Y
No affiliation info available
Chen ZY
No affiliation info available
Wang XB
No affiliation info available

MeSH

AllelesChi-Square DistributionChinaDNADNA FingerprintingElectrophoresis, CapillaryEthnic GroupsForensic SciencesGene FrequencyGenetics, PopulationGenotypeGeographyHeterozygoteHumansMicrosatellite RepeatsPolymerase Chain ReactionPolymorphism, GeneticQuality ControlReference StandardsUrban Population

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19083797

Citation

Wu, Yuan-Ming, et al. "Genetic Polymorphisms of 15 STR Loci in Chinese Han Population Living in Xi'an City of Shaanxi Province." Forensic Science International. Genetics, vol. 2, no. 2, 2008, pp. e15-8.
Wu YM, Zhang XN, Zhou Y, et al. Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi'an city of Shaanxi Province. Forensic Sci Int Genet. 2008;2(2):e15-8.
Wu, Y. M., Zhang, X. N., Zhou, Y., Chen, Z. Y., & Wang, X. B. (2008). Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi'an city of Shaanxi Province. Forensic Science International. Genetics, 2(2), e15-8. https://doi.org/10.1016/j.fsigen.2007.11.003
Wu YM, et al. Genetic Polymorphisms of 15 STR Loci in Chinese Han Population Living in Xi'an City of Shaanxi Province. Forensic Sci Int Genet. 2008;2(2):e15-8. PubMed PMID: 19083797.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Genetic polymorphisms of 15 STR loci in Chinese Han population living in Xi'an city of Shaanxi Province. AU - Wu,Yuan-Ming, AU - Zhang,Xiao-Nan, AU - Zhou,You, AU - Chen,Zhi-Yang, AU - Wang,Xiao-Bin, PY - 2007/07/19/received PY - 2007/10/24/revised PY - 2007/11/03/accepted PY - 2008/12/17/entrez PY - 2008/12/17/pubmed PY - 2009/2/28/medline SP - e15 EP - 8 JF - Forensic science international. Genetics JO - Forensic Sci Int Genet VL - 2 IS - 2 N2 - Fifteen autosomal STRs loci were analyzed from a population sample of 446 unrelated healthy individuals of Chinese Han population residing in Xi'an city of Shaanxi Province using a multiplex PCR system. We report allele frequencies distribution and statistical parameters for all STR loci, D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA. The observed genotype frequencies and expected of genotype frequencies were evaluated by chi(2)-test and the Fisher exact tests. Chi-Square test showed all STR loci were in Hardy-Weinberg equilibrium (p<0.05). Our studied population data were compared with the previously published population data of other ethnics or areas. After comparing, significant differences were found between Chinese Han population in Xi'an and Korean, Tibetan, Uigur, Chinese Han population in Guangdong Province, Hui population, Chinese Salar, Dongxiang and Tu ethnic minority living in Qinghai Province of China at some loci. The forensic parameters from the data showed high values. The data in the present study can be used greatly for routine forensic application in the region of Xi'an city. SN - 1878-0326 UR - https://www.unboundmedicine.com/medline/citation/19083797/Genetic_polymorphisms_of_15_STR_loci_in_Chinese_Han_population_living_in_Xi'an_city_of_Shaanxi_Province_ DB - PRIME DP - Unbound Medicine ER -