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Relief of radiation-induced oral mucositis in head and neck cancer.
Cancer Nurs. 2009 Jan-Feb; 32(1):82-7.CN

Abstract

This study was a prospective, randomized clinical trial carried out to explore the efficacy of payayor in the prevention and relief of radiation-induced oral mucositis compared with benzydamine. Sixty patients with head and neck cancer, who have started to receive radiotherapy and met predetermined criteria, were randomly assigned into each group to use assigned products 3 times a day from the first to the last day of radiation. The first group used glycerin payayor, a Thai prepared herbal product, by dripping it into the mouth. Another group rinsed their mouths with benzydamine hydrochloride. The World Health Organization Mucositis Grading System was used to assess oral status every week and 2 weeks after radiation. Comparison of time to the onset, pain, severity, xerostomia, postponement of treatment, satisfaction of the solution, and body weight between the 2 groups was performed by t test. The average time to the onset of oral mucositis in the payayor group was significantly later, and its severity and pain score were less than those of the benzydamine group throughout the study period. Significantly higher satisfaction with the solution and higher body weight at the end of the study were shown in the payayor group. Payayor seemed to be superior to benzydamine for preventing and relieving radiation-induced oral mucositis.

Authors+Show Affiliations

Department of Nursing, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19104205

Citation

Putwatana, Panwadee, et al. "Relief of Radiation-induced Oral Mucositis in Head and Neck Cancer." Cancer Nursing, vol. 32, no. 1, 2009, pp. 82-7.
Putwatana P, Sanmanowong P, Oonprasertpong L, et al. Relief of radiation-induced oral mucositis in head and neck cancer. Cancer Nurs. 2009;32(1):82-7.
Putwatana, P., Sanmanowong, P., Oonprasertpong, L., Junda, T., Pitiporn, S., & Narkwong, L. (2009). Relief of radiation-induced oral mucositis in head and neck cancer. Cancer Nursing, 32(1), 82-7. https://doi.org/10.1097/01.NCC.0000343362.68129.ed
Putwatana P, et al. Relief of Radiation-induced Oral Mucositis in Head and Neck Cancer. Cancer Nurs. 2009 Jan-Feb;32(1):82-7. PubMed PMID: 19104205.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relief of radiation-induced oral mucositis in head and neck cancer. AU - Putwatana,Panwadee, AU - Sanmanowong,Phichanee, AU - Oonprasertpong,Ladawal, AU - Junda,Tiraporn, AU - Pitiporn,Supaporn, AU - Narkwong,Ladawan, PY - 2008/12/24/entrez PY - 2008/12/24/pubmed PY - 2009/2/27/medline SP - 82 EP - 7 JF - Cancer nursing JO - Cancer Nurs VL - 32 IS - 1 N2 - This study was a prospective, randomized clinical trial carried out to explore the efficacy of payayor in the prevention and relief of radiation-induced oral mucositis compared with benzydamine. Sixty patients with head and neck cancer, who have started to receive radiotherapy and met predetermined criteria, were randomly assigned into each group to use assigned products 3 times a day from the first to the last day of radiation. The first group used glycerin payayor, a Thai prepared herbal product, by dripping it into the mouth. Another group rinsed their mouths with benzydamine hydrochloride. The World Health Organization Mucositis Grading System was used to assess oral status every week and 2 weeks after radiation. Comparison of time to the onset, pain, severity, xerostomia, postponement of treatment, satisfaction of the solution, and body weight between the 2 groups was performed by t test. The average time to the onset of oral mucositis in the payayor group was significantly later, and its severity and pain score were less than those of the benzydamine group throughout the study period. Significantly higher satisfaction with the solution and higher body weight at the end of the study were shown in the payayor group. Payayor seemed to be superior to benzydamine for preventing and relieving radiation-induced oral mucositis. SN - 1538-9804 UR - https://www.unboundmedicine.com/medline/citation/19104205/Relief_of_radiation_induced_oral_mucositis_in_head_and_neck_cancer_ L2 - http://dx.doi.org/10.1097/01.NCC.0000343362.68129.ed DB - PRIME DP - Unbound Medicine ER -