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Non-aqueous capillary electrophoresis 2005-2008.
Electrophoresis. 2009 Jan; 30(1):36-49.E

Abstract

This review article presents recent developments and applications of non-aqueous capillary electrophoresis (NACE): The text covers the period from the previous review (L. Geiser, J. L. Veuthey, Electrophoresis 2007, 28, 45-57) to summer 2008. We focus primarily on the analysis of pharmaceutical drugs by non-aqueous solvents in CZE within different matrices including phytochemical plant extracts and biological fluids. We also extend our discussion to other application fields (e.g. food material and environmental samples) and to chiral separations by NACE. This review focuses on practical aspects of NACE, illustrating which organic solvents and electrolytes are best suited for NACE analyses and their compatibilities with different detection techniques, including UV, LIF and MS. The review emphasizes the interests of using non-aqueous solvents in place of water for the analysis by CZE, and as an alternative to MEKC.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Geiser L
Biomedical Proteomics Research Group, Department of Bioinformatics and Structural Biology, University of Geneva, Geneva, Switzerland.
Veuthey JL
No affiliation info available

MeSH

Body FluidsChromatography, Micellar Electrokinetic CapillaryElectrolytesElectrophoresis, CapillaryEnvironmental PollutionFood AnalysisHydrogen-Ion ConcentrationIsomerismMass SpectrometryPlant ExtractsSensitivity and SpecificitySolubilitySolventsSpectrometry, FluorescenceSpectrophotometry, Ultraviolet

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19107701

Citation

Geiser, Laurent, and Jean-Luc Veuthey. "Non-aqueous Capillary Electrophoresis 2005-2008." Electrophoresis, vol. 30, no. 1, 2009, pp. 36-49.
Geiser L, Veuthey JL. Non-aqueous capillary electrophoresis 2005-2008. Electrophoresis. 2009;30(1):36-49.
Geiser, L., & Veuthey, J. L. (2009). Non-aqueous capillary electrophoresis 2005-2008. Electrophoresis, 30(1), 36-49. https://doi.org/10.1002/elps.200800494
Geiser L, Veuthey JL. Non-aqueous Capillary Electrophoresis 2005-2008. Electrophoresis. 2009;30(1):36-49. PubMed PMID: 19107701.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Non-aqueous capillary electrophoresis 2005-2008. AU - Geiser,Laurent, AU - Veuthey,Jean-Luc, PY - 2008/12/25/entrez PY - 2008/12/25/pubmed PY - 2009/8/8/medline SP - 36 EP - 49 JF - Electrophoresis JO - Electrophoresis VL - 30 IS - 1 N2 - This review article presents recent developments and applications of non-aqueous capillary electrophoresis (NACE): The text covers the period from the previous review (L. Geiser, J. L. Veuthey, Electrophoresis 2007, 28, 45-57) to summer 2008. We focus primarily on the analysis of pharmaceutical drugs by non-aqueous solvents in CZE within different matrices including phytochemical plant extracts and biological fluids. We also extend our discussion to other application fields (e.g. food material and environmental samples) and to chiral separations by NACE. This review focuses on practical aspects of NACE, illustrating which organic solvents and electrolytes are best suited for NACE analyses and their compatibilities with different detection techniques, including UV, LIF and MS. The review emphasizes the interests of using non-aqueous solvents in place of water for the analysis by CZE, and as an alternative to MEKC. SN - 1522-2683 UR - https://www.unboundmedicine.com/medline/citation/19107701/Non_aqueous_capillary_electrophoresis_2005_2008_ DB - PRIME DP - Unbound Medicine ER -