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Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa.
Phytother Res. 2009 Jan; 23(1):123-5.PR

Abstract

From the whole plant of Gentianopsis paludosa seven compounds were isolated and identified to be 1,7-dihydroxy-3,8-dimethoxyxanthone (1), 1,7,8-trihydroxy-3-methoxyxanthone (2), 1-hydroxy-3,7,8-trimethoxyxanthone (3), 1,8-dihydroxy-2,6-dimethoxyxanthone (4), oleanolic acid (5), 4',5,7-trihydroxyflavone (6) and luteolin-7-O-glucoside (7). Compounds 1, 2, 3 and 5 showed modest inhibitory effect against the growth of Mycobacterium smegmatis and M. tuberculosis.

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Authors+Show Affiliations

Yeung MF
School of Chinese Medicine, the Chinese University of Hong Kong, Hong Kong.
Lau CB
No affiliation info available
Chan RC
No affiliation info available
Zong Y
No affiliation info available
Che CT
No affiliation info available

MeSH

Anti-Bacterial AgentsGentianaceaeMolecular StructureMycobacterium smegmatisMycobacterium tuberculosisPlant ExtractsPlants, MedicinalTibetXanthones

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19107824

Citation

Yeung, Ming-Fai, et al. "Search for Antimycobacterial Constituents From a Tibetan Medicinal Plant, Gentianopsis Paludosa." Phytotherapy Research : PTR, vol. 23, no. 1, 2009, pp. 123-5.
Yeung MF, Lau CB, Chan RC, et al. Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa. Phytother Res. 2009;23(1):123-5.
Yeung, M. F., Lau, C. B., Chan, R. C., Zong, Y., & Che, C. T. (2009). Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa. Phytotherapy Research : PTR, 23(1), 123-5. https://doi.org/10.1002/ptr.2506
Yeung MF, et al. Search for Antimycobacterial Constituents From a Tibetan Medicinal Plant, Gentianopsis Paludosa. Phytother Res. 2009;23(1):123-5. PubMed PMID: 19107824.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa. AU - Yeung,Ming-Fai, AU - Lau,Clara B S, AU - Chan,Raphael C Y, AU - Zong,Yuying, AU - Che,Chun-Tao, PY - 2008/12/25/entrez PY - 2008/12/25/pubmed PY - 2009/2/12/medline SP - 123 EP - 5 JF - Phytotherapy research : PTR JO - Phytother Res VL - 23 IS - 1 N2 - From the whole plant of Gentianopsis paludosa seven compounds were isolated and identified to be 1,7-dihydroxy-3,8-dimethoxyxanthone (1), 1,7,8-trihydroxy-3-methoxyxanthone (2), 1-hydroxy-3,7,8-trimethoxyxanthone (3), 1,8-dihydroxy-2,6-dimethoxyxanthone (4), oleanolic acid (5), 4',5,7-trihydroxyflavone (6) and luteolin-7-O-glucoside (7). Compounds 1, 2, 3 and 5 showed modest inhibitory effect against the growth of Mycobacterium smegmatis and M. tuberculosis. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/19107824/Search_for_antimycobacterial_constituents_from_a_Tibetan_medicinal_plant_Gentianopsis_paludosa_ L2 - https://doi.org/10.1002/ptr.2506 DB - PRIME DP - Unbound Medicine ER -