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[Vaccinations for the traveling adult solid organ transplant recipient (excluding hematopoietic stem cell transplant recipients)].
Med Mal Infect. 2009 Apr; 39(4):225-33.MM

Abstract

Progress in transplantation technique has offered a growing number of solid organ transplant recipients the opportunity to travel to tropical and low-income countries. The issue of vaccine-preventable diseases is a challenging question in immunocompromised patients including those with solid organ transplant. Since the response to vaccines is weakened in case of chronic organ failure, candidates should be vaccinated early in the course of the disease. Clinicians should implement a vaccinal strategy until the patient is scheduled for transplantation and monitor its efficacy by serological assays. Live attenuated vaccines (such as yellow fever, measles-mumps-rubella, or chicken pox) are contra-indicated in solid organ transplant recipients and, when indicated, should be administered prior to transplantation, particularly in foreign-born patients highly likely to visit friends and relatives in endemic areas. Vaccinations for transplant recipients considering international travel should be realized according to the risk of acquiring vaccine-preventable diseases but also on both tolerance and immune response which are affected by degree and duration of immunosuppression, comorbidities, and type of organ transplanted. Routine and specific vaccinations for solid organ transplant recipients, as well as travel-related vaccination (such as hepatitis A, typhoid, meningococcal meningitis, rabies, tick-born encephalitis, Japanese encephalitis, and cholera) should be considered during a specific pretravel medical consultation. However, vaccination should be avoided in the 6 months following transplantation when patients are usually receiving the highest doses of immunosuppressive drugs. In this comprehensive review, we provide vaccination schedules based on published studies and guidelines for vaccination of solid organ transplant recipients.

Authors+Show Affiliations

Unité de maladies infectieuses et tropicales, hôpital universitaire Paul-Brousse, Assistance publique-Hôpitaux de Paris, faculté de médecine, université Paris Sud-11, 12-14, 94804 Villejuif cedex, France. benjamin.wyplosz@pbr.aphp.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

19111416

Citation

Wyplosz, B, et al. "[Vaccinations for the Traveling Adult Solid Organ Transplant Recipient (excluding Hematopoietic Stem Cell Transplant Recipients)]." Medecine Et Maladies Infectieuses, vol. 39, no. 4, 2009, pp. 225-33.
Wyplosz B, Van der Vliet D, Consigny PH, et al. [Vaccinations for the traveling adult solid organ transplant recipient (excluding hematopoietic stem cell transplant recipients)]. Med Mal Infect. 2009;39(4):225-33.
Wyplosz, B., Van der Vliet, D., Consigny, P. H., Calmus, Y., Mamzer-Bruneel, M. F., Guillemain, R., Malvy, D., Samuel, D., Vittecoq, D., & Launay, O. (2009). [Vaccinations for the traveling adult solid organ transplant recipient (excluding hematopoietic stem cell transplant recipients)]. Medecine Et Maladies Infectieuses, 39(4), 225-33. https://doi.org/10.1016/j.medmal.2008.11.006
Wyplosz B, et al. [Vaccinations for the Traveling Adult Solid Organ Transplant Recipient (excluding Hematopoietic Stem Cell Transplant Recipients)]. Med Mal Infect. 2009;39(4):225-33. PubMed PMID: 19111416.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Vaccinations for the traveling adult solid organ transplant recipient (excluding hematopoietic stem cell transplant recipients)]. AU - Wyplosz,B, AU - Van der Vliet,D, AU - Consigny,P H, AU - Calmus,Y, AU - Mamzer-Bruneel,M F, AU - Guillemain,R, AU - Malvy,D, AU - Samuel,D, AU - Vittecoq,D, AU - Launay,O, AU - ,, Y1 - 2008/12/25/ PY - 2008/05/04/received PY - 2008/10/04/revised PY - 2008/11/14/accepted PY - 2008/12/30/entrez PY - 2008/12/30/pubmed PY - 2009/7/29/medline SP - 225 EP - 33 JF - Medecine et maladies infectieuses JO - Med Mal Infect VL - 39 IS - 4 N2 - Progress in transplantation technique has offered a growing number of solid organ transplant recipients the opportunity to travel to tropical and low-income countries. The issue of vaccine-preventable diseases is a challenging question in immunocompromised patients including those with solid organ transplant. Since the response to vaccines is weakened in case of chronic organ failure, candidates should be vaccinated early in the course of the disease. Clinicians should implement a vaccinal strategy until the patient is scheduled for transplantation and monitor its efficacy by serological assays. Live attenuated vaccines (such as yellow fever, measles-mumps-rubella, or chicken pox) are contra-indicated in solid organ transplant recipients and, when indicated, should be administered prior to transplantation, particularly in foreign-born patients highly likely to visit friends and relatives in endemic areas. Vaccinations for transplant recipients considering international travel should be realized according to the risk of acquiring vaccine-preventable diseases but also on both tolerance and immune response which are affected by degree and duration of immunosuppression, comorbidities, and type of organ transplanted. Routine and specific vaccinations for solid organ transplant recipients, as well as travel-related vaccination (such as hepatitis A, typhoid, meningococcal meningitis, rabies, tick-born encephalitis, Japanese encephalitis, and cholera) should be considered during a specific pretravel medical consultation. However, vaccination should be avoided in the 6 months following transplantation when patients are usually receiving the highest doses of immunosuppressive drugs. In this comprehensive review, we provide vaccination schedules based on published studies and guidelines for vaccination of solid organ transplant recipients. SN - 0399-077X UR - https://www.unboundmedicine.com/medline/citation/19111416/[Vaccinations_for_the_traveling_adult_solid_organ_transplant_recipient__excluding_hematopoietic_stem_cell_transplant_recipients_]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0399-077X(08)00422-8 DB - PRIME DP - Unbound Medicine ER -