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Reported analgesic administration to rabbits, pigs, sheep, dogs and non-human primates undergoing experimental surgical procedures.
Lab Anim 2009; 43(3):232-8LA

Abstract

Reported analgesic use following experimental surgery is low in rodents and there has been little published information on the frequency of analgesic use in other laboratory species. A structured literature review was conducted to examine analgesic administration in larger laboratory animals. The Scirus search engine was used to identify studies published in peer-reviewed journals that reported carrying out experimental surgery on 'large' laboratory animals, specifically rabbits, pigs, sheep, dogs and non-human primates. Seventy-four studies between 2000 and 2001 and 75 studies between 2005 and 2006 were included in the review. There was an increase in the reported administration of systemic analgesics to these species from 50% in 2000-2001 to 63% in 2005-2006. When all agents with analgesic properties were considered (systemic analgesics, local anaesthetics and anaesthetics with analgesic components), the proportion of papers that reported some form of analgesic administration to 'large' laboratory animals increased from 86% in 2000-2001 to 89% in 2005-2006. Overall rabbits, pigs, sheep, dogs and non-human primates were more likely to receive analgesics following potentially painful experimental procedures than has been reported in laboratory rodents but analgesic administration to 'large' laboratory species is still not optimal.

Authors+Show Affiliations

Comparative Biology Centre, Medical School, Framlington Place, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19116294

Citation

Coulter, C A., et al. "Reported Analgesic Administration to Rabbits, Pigs, Sheep, Dogs and Non-human Primates Undergoing Experimental Surgical Procedures." Laboratory Animals, vol. 43, no. 3, 2009, pp. 232-8.
Coulter CA, Flecknell PA, Richardson CA. Reported analgesic administration to rabbits, pigs, sheep, dogs and non-human primates undergoing experimental surgical procedures. Lab Anim. 2009;43(3):232-8.
Coulter, C. A., Flecknell, P. A., & Richardson, C. A. (2009). Reported analgesic administration to rabbits, pigs, sheep, dogs and non-human primates undergoing experimental surgical procedures. Laboratory Animals, 43(3), pp. 232-8. doi:10.1258/la.2008.008021.
Coulter CA, Flecknell PA, Richardson CA. Reported Analgesic Administration to Rabbits, Pigs, Sheep, Dogs and Non-human Primates Undergoing Experimental Surgical Procedures. Lab Anim. 2009;43(3):232-8. PubMed PMID: 19116294.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Reported analgesic administration to rabbits, pigs, sheep, dogs and non-human primates undergoing experimental surgical procedures. AU - Coulter,C A, AU - Flecknell,P A, AU - Richardson,C A, Y1 - 2008/12/30/ PY - 2009/1/1/entrez PY - 2009/1/1/pubmed PY - 2009/9/18/medline SP - 232 EP - 8 JF - Laboratory animals JO - Lab. Anim. VL - 43 IS - 3 N2 - Reported analgesic use following experimental surgery is low in rodents and there has been little published information on the frequency of analgesic use in other laboratory species. A structured literature review was conducted to examine analgesic administration in larger laboratory animals. The Scirus search engine was used to identify studies published in peer-reviewed journals that reported carrying out experimental surgery on 'large' laboratory animals, specifically rabbits, pigs, sheep, dogs and non-human primates. Seventy-four studies between 2000 and 2001 and 75 studies between 2005 and 2006 were included in the review. There was an increase in the reported administration of systemic analgesics to these species from 50% in 2000-2001 to 63% in 2005-2006. When all agents with analgesic properties were considered (systemic analgesics, local anaesthetics and anaesthetics with analgesic components), the proportion of papers that reported some form of analgesic administration to 'large' laboratory animals increased from 86% in 2000-2001 to 89% in 2005-2006. Overall rabbits, pigs, sheep, dogs and non-human primates were more likely to receive analgesics following potentially painful experimental procedures than has been reported in laboratory rodents but analgesic administration to 'large' laboratory species is still not optimal. SN - 0023-6772 UR - https://www.unboundmedicine.com/medline/citation/19116294/Reported_analgesic_administration_to_rabbits_pigs_sheep_dogs_and_non_human_primates_undergoing_experimental_surgical_procedures L2 - http://journals.sagepub.com/doi/full/10.1258/la.2008.008021?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -