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[Multifocal motor neuropathy: a retrospective study of sensory nerve conduction velocities in long-term follow-up of 21 patients].
Rev Neurol (Paris). 2009 Mar; 165(3):243-8.RN

Abstract

INTRODUCTION

Multifocal motor neuropathy is a well described condition characterized by slowly progressive, predominantly distal, asymmetric limb weakness and wasting, predominantly in the arms within an anatomical distribution of individual motor nerves, with minimal or no sensory involvement.

METHOD

The aim of this retrospective study was to look for a significant reduction of the amplitude of sensory potentials in a cohort of 21 patients with defined multifocal motor neuropathy according to the Workshop Report criteria [Workshop Report, 2001. 79th ENMC International Workshop. Multifocal motor neuropathy 14-15 April 2000, Hilversum. The Netherlands. Muscle Nerve 11, 309-314], within a follow-up of at least 3 years.

RESULT

Thirteen patients (62%) (Group 1) had a reduction of the amplitude of at least one sensory potential, of whom four patients had abnormalities of two or more sensory potentials, while eight patients (Group 2) had no abnormality. No significant differences were found for gender, age at onset, number of involved motor nerves, CSF protein count, presence/absence of anti-GM1 serum antibodies and response to IgIV between the two groups.

CONCLUSION

This study underlines the difficulty in defining criteria for multifocal motor neuropathies capable of distinguishing them from other chronic acquired demyelinating polyneuropathies, and mainly from multifocal acquired demyelinating sensory and motor (MADSAM) neuropathy, also called Lewis-Sumner's syndrome.

Authors+Show Affiliations

Centre national de référence maladies neuromusculaires rares, bâtiment Babinski, hôpital Pitié-Salpêtrière, AP-HP, 47, boulevard de l'Hôpital, 75651 Paris cedex 13, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

19118851

Citation

Lievens, I, et al. "[Multifocal Motor Neuropathy: a Retrospective Study of Sensory Nerve Conduction Velocities in Long-term Follow-up of 21 Patients]." Revue Neurologique, vol. 165, no. 3, 2009, pp. 243-8.
Lievens I, Fournier E, Viala K, et al. [Multifocal motor neuropathy: a retrospective study of sensory nerve conduction velocities in long-term follow-up of 21 patients]. Rev Neurol (Paris). 2009;165(3):243-8.
Lievens, I., Fournier, E., Viala, K., Maisonobe, T., Bouche, P., & Léger, J. M. (2009). [Multifocal motor neuropathy: a retrospective study of sensory nerve conduction velocities in long-term follow-up of 21 patients]. Revue Neurologique, 165(3), 243-8. https://doi.org/10.1016/j.neurol.2008.10.018
Lievens I, et al. [Multifocal Motor Neuropathy: a Retrospective Study of Sensory Nerve Conduction Velocities in Long-term Follow-up of 21 Patients]. Rev Neurol (Paris). 2009;165(3):243-8. PubMed PMID: 19118851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Multifocal motor neuropathy: a retrospective study of sensory nerve conduction velocities in long-term follow-up of 21 patients]. AU - Lievens,I, AU - Fournier,E, AU - Viala,K, AU - Maisonobe,T, AU - Bouche,P, AU - Léger,J-M, Y1 - 2008/12/31/ PY - 2008/06/25/received PY - 2008/09/03/revised PY - 2008/10/08/accepted PY - 2009/1/3/entrez PY - 2009/1/3/pubmed PY - 2009/5/9/medline SP - 243 EP - 8 JF - Revue neurologique JO - Rev Neurol (Paris) VL - 165 IS - 3 N2 - INTRODUCTION: Multifocal motor neuropathy is a well described condition characterized by slowly progressive, predominantly distal, asymmetric limb weakness and wasting, predominantly in the arms within an anatomical distribution of individual motor nerves, with minimal or no sensory involvement. METHOD: The aim of this retrospective study was to look for a significant reduction of the amplitude of sensory potentials in a cohort of 21 patients with defined multifocal motor neuropathy according to the Workshop Report criteria [Workshop Report, 2001. 79th ENMC International Workshop. Multifocal motor neuropathy 14-15 April 2000, Hilversum. The Netherlands. Muscle Nerve 11, 309-314], within a follow-up of at least 3 years. RESULT: Thirteen patients (62%) (Group 1) had a reduction of the amplitude of at least one sensory potential, of whom four patients had abnormalities of two or more sensory potentials, while eight patients (Group 2) had no abnormality. No significant differences were found for gender, age at onset, number of involved motor nerves, CSF protein count, presence/absence of anti-GM1 serum antibodies and response to IgIV between the two groups. CONCLUSION: This study underlines the difficulty in defining criteria for multifocal motor neuropathies capable of distinguishing them from other chronic acquired demyelinating polyneuropathies, and mainly from multifocal acquired demyelinating sensory and motor (MADSAM) neuropathy, also called Lewis-Sumner's syndrome. SN - 0035-3787 UR - https://www.unboundmedicine.com/medline/citation/19118851/[Multifocal_motor_neuropathy:_a_retrospective_study_of_sensory_nerve_conduction_velocities_in_long_term_follow_up_of_21_patients]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0035-3787(08)00591-2 DB - PRIME DP - Unbound Medicine ER -