Tags

Type your tag names separated by a space and hit enter

[The importance of the at risk COPD patients (Stage 0) and clinical differences].
Tuberk Toraks. 2008; 56(4):382-9.TT

Abstract

Chronic obstructive pulmonary disease (COPD) is an important world health problem and estimated that the prevalance will increase. In early period this disease in symptomatic with cough, sputum and dyspnea. FEV(1)/FVC was greater than 70% in early period and it was accepted as stage 0 (at risk) COPD before the last The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline. In last GOLD guideline this stage is excluded. In this study we aimed to find out the clinical differences between this cases and healty population. Prospectively spirometric measures, exercise capacity, dyspnea index, saturation of O2 (SpO2) and life quality are compared between two groups. We evaluated 58 at risk cases and 63 healty adults. There was no difference between two groups about age, sex and smoke cessations. In at risk group 77.6% cough, 53.4% sputum and 62.1% dyspnea were the symptoms. In currently smokers cough and sputum were dominant symptoms however dyspnea was dominant symptom in exsmokers. Absolute FEV1, FEF25-75 values, predicted FEV1/FVC, FEV1, FVC, PEF, FEF25-75% values are lower in at risk group (p<0.05). Mean six minutes walking distance were lower in at risk group but not statistically significant (p>0.05). Dyspnea index before walking were not different between two groups (p>0.05) however dyspnea index after walking and change were higher in at risk group (p>0.05). Resting SpO2, SpO2 after exercise and desaturation with exercise (DeltaSpO2) were lower in at risk group but not statistically significant. Physical and mental components of Short Form 36 (SF36) scores were similar in two groups (p>0.05). COPD at risk group is separated from healty population with chronic respiratory symptoms and inhalation of smoke or other irritans. In these cases spirometric measures are significantly worse although functional parametres are similar with healty population, so it is thought about being a subclinical disease. These cases must be educated about COPD, encouraged about giving up smoking and prevented occurring COPD.

Authors+Show Affiliations

Nizip State Hospital, Gaziantep, Turkey. nkomus@yahoo.comNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

tur

PubMed ID

19123073

Citation

Kömüs, Nuray, et al. "[The Importance of the at Risk COPD Patients (Stage 0) and Clinical Differences]." Tuberkuloz Ve Toraks, vol. 56, no. 4, 2008, pp. 382-9.
Kömüs N, Tertemiz KC, Sevinç C. [The importance of the at risk COPD patients (Stage 0) and clinical differences]. Tuberk Toraks. 2008;56(4):382-9.
Kömüs, N., Tertemiz, K. C., & Sevinç, C. (2008). [The importance of the at risk COPD patients (Stage 0) and clinical differences]. Tuberkuloz Ve Toraks, 56(4), 382-9.
Kömüs N, Tertemiz KC, Sevinç C. [The Importance of the at Risk COPD Patients (Stage 0) and Clinical Differences]. Tuberk Toraks. 2008;56(4):382-9. PubMed PMID: 19123073.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The importance of the at risk COPD patients (Stage 0) and clinical differences]. AU - Kömüs,Nuray, AU - Tertemiz,Kemal Can, AU - Sevinç,Can, PY - 2009/1/6/entrez PY - 2009/1/6/pubmed PY - 2009/4/28/medline SP - 382 EP - 9 JF - Tuberkuloz ve toraks JO - Tuberk Toraks VL - 56 IS - 4 N2 - Chronic obstructive pulmonary disease (COPD) is an important world health problem and estimated that the prevalance will increase. In early period this disease in symptomatic with cough, sputum and dyspnea. FEV(1)/FVC was greater than 70% in early period and it was accepted as stage 0 (at risk) COPD before the last The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guideline. In last GOLD guideline this stage is excluded. In this study we aimed to find out the clinical differences between this cases and healty population. Prospectively spirometric measures, exercise capacity, dyspnea index, saturation of O2 (SpO2) and life quality are compared between two groups. We evaluated 58 at risk cases and 63 healty adults. There was no difference between two groups about age, sex and smoke cessations. In at risk group 77.6% cough, 53.4% sputum and 62.1% dyspnea were the symptoms. In currently smokers cough and sputum were dominant symptoms however dyspnea was dominant symptom in exsmokers. Absolute FEV1, FEF25-75 values, predicted FEV1/FVC, FEV1, FVC, PEF, FEF25-75% values are lower in at risk group (p<0.05). Mean six minutes walking distance were lower in at risk group but not statistically significant (p>0.05). Dyspnea index before walking were not different between two groups (p>0.05) however dyspnea index after walking and change were higher in at risk group (p>0.05). Resting SpO2, SpO2 after exercise and desaturation with exercise (DeltaSpO2) were lower in at risk group but not statistically significant. Physical and mental components of Short Form 36 (SF36) scores were similar in two groups (p>0.05). COPD at risk group is separated from healty population with chronic respiratory symptoms and inhalation of smoke or other irritans. In these cases spirometric measures are significantly worse although functional parametres are similar with healty population, so it is thought about being a subclinical disease. These cases must be educated about COPD, encouraged about giving up smoking and prevented occurring COPD. SN - 0494-1373 UR - https://www.unboundmedicine.com/medline/citation/19123073/[The_importance_of_the_at_risk_COPD_patients__Stage_0__and_clinical_differences]_ L2 - https://medlineplus.gov/breathingproblems.html DB - PRIME DP - Unbound Medicine ER -