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Nutritional treatment of chronic liver failure.
Hepatol Res 2008; 38 Suppl 1:S93-S101HR

Abstract

The liver plays a central role in the regulation of nutrition by trafficking the metabolism of nutrients, their distribution and appropriate use. Accordingly, protein-energy malnutrition is common in patients with advanced liver disease, and it is a significant prognostic factor, affecting survival, the success of liver transplantation and quality of life. Clinical guidelines for the assessment and treatment of malnutrition have been issued by International societies, suggesting that nutritional therapy should be instituted in all patients where requirements are not adequately met by diet. The supplementation of the diet with amino acids (mainly branched-chain amino acids) and trace elements may improve nutritional status, liver function and hepatic encephalopathy. Nutritional issues should be carefully considered in Liver Units treating patients with advanced cirrhosis, and long-term, carefully controlled studies are needed to better define the type of nutritional support and the amount and timing of administration.

Authors+Show Affiliations

Unit of Internal Medicine, Alma MAter Studiorum University, Bologna, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19125960

Citation

Bianchi, Giampaolo, et al. "Nutritional Treatment of Chronic Liver Failure." Hepatology Research : the Official Journal of the Japan Society of Hepatology, vol. 38 Suppl 1, 2008, pp. S93-S101.
Bianchi G, Marzocchi R, Lorusso C, et al. Nutritional treatment of chronic liver failure. Hepatol Res. 2008;38 Suppl 1:S93-S101.
Bianchi, G., Marzocchi, R., Lorusso, C., Ridolfi, V., & Marchesini, G. (2008). Nutritional treatment of chronic liver failure. Hepatology Research : the Official Journal of the Japan Society of Hepatology, 38 Suppl 1, pp. S93-S101. doi:10.1111/j.1872-034X.2008.00433.x.
Bianchi G, et al. Nutritional Treatment of Chronic Liver Failure. Hepatol Res. 2008;38 Suppl 1:S93-S101. PubMed PMID: 19125960.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nutritional treatment of chronic liver failure. AU - Bianchi,Giampaolo, AU - Marzocchi,Rebecca, AU - Lorusso,Caterina, AU - Ridolfi,Valentina, AU - Marchesini,Giulio, PY - 2009/1/8/entrez PY - 2009/1/8/pubmed PY - 2009/1/8/medline SP - S93 EP - S101 JF - Hepatology research : the official journal of the Japan Society of Hepatology JO - Hepatol. Res. VL - 38 Suppl 1 N2 - The liver plays a central role in the regulation of nutrition by trafficking the metabolism of nutrients, their distribution and appropriate use. Accordingly, protein-energy malnutrition is common in patients with advanced liver disease, and it is a significant prognostic factor, affecting survival, the success of liver transplantation and quality of life. Clinical guidelines for the assessment and treatment of malnutrition have been issued by International societies, suggesting that nutritional therapy should be instituted in all patients where requirements are not adequately met by diet. The supplementation of the diet with amino acids (mainly branched-chain amino acids) and trace elements may improve nutritional status, liver function and hepatic encephalopathy. Nutritional issues should be carefully considered in Liver Units treating patients with advanced cirrhosis, and long-term, carefully controlled studies are needed to better define the type of nutritional support and the amount and timing of administration. SN - 1386-6346 UR - https://www.unboundmedicine.com/medline/citation/19125960/Nutritional_treatment_of_chronic_liver_failure_ L2 - https://doi.org/10.1111/j.1872-034X.2008.00433.x DB - PRIME DP - Unbound Medicine ER -