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Mammographically guided fine-needle aspiration biopsy of nonpalpable breast lesions. Can it replace open biopsy?
Cancer. 1991 Nov 01; 68(9):2007-11.C

Abstract

The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but three cancers were not detected in aspirates judged to be sufficient for diagnosis. In addition, 19 aspirates were reported to be insufficient, and 4 of these were obtained from lesions histologically proven to be adenocarcinoma. Although no false-positive diagnoses were encountered, the technique demonstrated a sensitivity of 78% and a diagnostic accuracy of 94% for adequate specimens. In this study, mammographically guided FNA was insufficiently sensitive to replace open biopsy for the diagnosis of nonpalpable breast lesions.

Authors+Show Affiliations

Department of Pathology, University of California, Los Angeles Medical Center.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1913550

Citation

Layfield, L J., et al. "Mammographically Guided Fine-needle Aspiration Biopsy of Nonpalpable Breast Lesions. Can It Replace Open Biopsy?" Cancer, vol. 68, no. 9, 1991, pp. 2007-11.
Layfield LJ, Parkinson B, Wong J, et al. Mammographically guided fine-needle aspiration biopsy of nonpalpable breast lesions. Can it replace open biopsy? Cancer. 1991;68(9):2007-11.
Layfield, L. J., Parkinson, B., Wong, J., Giuliano, A. E., & Bassett, L. W. (1991). Mammographically guided fine-needle aspiration biopsy of nonpalpable breast lesions. Can it replace open biopsy? Cancer, 68(9), 2007-11.
Layfield LJ, et al. Mammographically Guided Fine-needle Aspiration Biopsy of Nonpalpable Breast Lesions. Can It Replace Open Biopsy. Cancer. 1991 Nov 1;68(9):2007-11. PubMed PMID: 1913550.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mammographically guided fine-needle aspiration biopsy of nonpalpable breast lesions. Can it replace open biopsy? AU - Layfield,L J, AU - Parkinson,B, AU - Wong,J, AU - Giuliano,A E, AU - Bassett,L W, PY - 1991/11/1/pubmed PY - 1991/11/1/medline PY - 1991/11/1/entrez SP - 2007 EP - 11 JF - Cancer JO - Cancer VL - 68 IS - 9 N2 - The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but three cancers were not detected in aspirates judged to be sufficient for diagnosis. In addition, 19 aspirates were reported to be insufficient, and 4 of these were obtained from lesions histologically proven to be adenocarcinoma. Although no false-positive diagnoses were encountered, the technique demonstrated a sensitivity of 78% and a diagnostic accuracy of 94% for adequate specimens. In this study, mammographically guided FNA was insufficiently sensitive to replace open biopsy for the diagnosis of nonpalpable breast lesions. SN - 0008-543X UR - https://www.unboundmedicine.com/medline/citation/1913550/Mammographically_guided_fine_needle_aspiration_biopsy_of_nonpalpable_breast_lesions__Can_it_replace_open_biopsy L2 - https://medlineplus.gov/breastcancer.html DB - PRIME DP - Unbound Medicine ER -