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Anti-Ma2 paraneoplastic encephalitis associated with testicular germ cell tumor treated by carboplatin, etoposide and bleomycin.
Int J Urol. 2008 Oct; 15(10):942-3.IJ

Abstract

Anti-Ma2-associated encephalitis is a paraneoplastic disorder that predominantly affects the limbic system, diencephalon and brainstem, and is usually associated with tumors of the testis. We report a 35-year-old man with a right testicular mass who presented with multiple neurological complains, and clinical, serological and radiological features compatible with anti-Ma2-associated encephalitis. After three courses of carboplatin, etoposide and bleomycin for metastatic testicular germ-cell tumor, all elevated tumor markers normalized and the retroperitoneal metastases disappeared, but the neurological disorder deteriorated. To our knowledge, this is the first case in which orchiectomy followed by carboplatin, etoposide and bleomycin for a testicular tumor with anti-Ma2 encephalitis was performed.

Authors+Show Affiliations

Department of Urology, International University of Health and Welfare, Mita Hospital, Tokyo, Japan. kimura@gb3.so-net.ne.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19138287

Citation

Kimura, Masaki, et al. "Anti-Ma2 Paraneoplastic Encephalitis Associated With Testicular Germ Cell Tumor Treated By Carboplatin, Etoposide and Bleomycin." International Journal of Urology : Official Journal of the Japanese Urological Association, vol. 15, no. 10, 2008, pp. 942-3.
Kimura M, Onozawa M, Fujisaki A, et al. Anti-Ma2 paraneoplastic encephalitis associated with testicular germ cell tumor treated by carboplatin, etoposide and bleomycin. Int J Urol. 2008;15(10):942-3.
Kimura, M., Onozawa, M., Fujisaki, A., Arakawa, T., Takeda, K., Dalmau, J., & Hattori, K. (2008). Anti-Ma2 paraneoplastic encephalitis associated with testicular germ cell tumor treated by carboplatin, etoposide and bleomycin. International Journal of Urology : Official Journal of the Japanese Urological Association, 15(10), 942-3. https://doi.org/10.1111/j.1442-2042.2008.02119.x
Kimura M, et al. Anti-Ma2 Paraneoplastic Encephalitis Associated With Testicular Germ Cell Tumor Treated By Carboplatin, Etoposide and Bleomycin. Int J Urol. 2008;15(10):942-3. PubMed PMID: 19138287.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anti-Ma2 paraneoplastic encephalitis associated with testicular germ cell tumor treated by carboplatin, etoposide and bleomycin. AU - Kimura,Masaki, AU - Onozawa,Mizuki, AU - Fujisaki,Akira, AU - Arakawa,Takashi, AU - Takeda,Katsuhiko, AU - Dalmau,Joseph, AU - Hattori,Kazunori, PY - 2009/1/14/entrez PY - 2009/1/14/pubmed PY - 2009/5/6/medline SP - 942 EP - 3 JF - International journal of urology : official journal of the Japanese Urological Association JO - Int J Urol VL - 15 IS - 10 N2 - Anti-Ma2-associated encephalitis is a paraneoplastic disorder that predominantly affects the limbic system, diencephalon and brainstem, and is usually associated with tumors of the testis. We report a 35-year-old man with a right testicular mass who presented with multiple neurological complains, and clinical, serological and radiological features compatible with anti-Ma2-associated encephalitis. After three courses of carboplatin, etoposide and bleomycin for metastatic testicular germ-cell tumor, all elevated tumor markers normalized and the retroperitoneal metastases disappeared, but the neurological disorder deteriorated. To our knowledge, this is the first case in which orchiectomy followed by carboplatin, etoposide and bleomycin for a testicular tumor with anti-Ma2 encephalitis was performed. SN - 1442-2042 UR - https://www.unboundmedicine.com/medline/citation/19138287/Anti_Ma2_paraneoplastic_encephalitis_associated_with_testicular_germ_cell_tumor_treated_by_carboplatin_etoposide_and_bleomycin_ L2 - https://doi.org/10.1111/j.1442-2042.2008.02119.x DB - PRIME DP - Unbound Medicine ER -