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The potential role of green tea catechins in the prevention of the metabolic syndrome - a review.
Phytochemistry. 2009 Jan; 70(1):11-24.P

Abstract

The metabolic syndrome (MetS) represents an emerging health burden for governments and health care providers. Particularly relevant for prevention and early management of MetS are lifestyle conditions including physical activity and the diet. It has been shown that green tea, when consumed on a daily basis, supports health. Many of the beneficial effects of green tea are related to its catechin, particularly (-)-epigallocatechin-3-gallate (EGCG), content. There is conclusive evidence from in vitro and animal studies which provide the concepts for underlying functional mechanisms of green tea catechins and their biological actions. An increasing number of human studies have explored the effects of green tea catechins on the major MetS conditions such as obesity, type-2 diabetes and cardiovascular risk factors. This article provides a comprehensive overview of the human studies addressing the potential benefits of green tea catechins on the MetS. The number of human studies in this field is still limited. However, the majority of human epidemiological and intervention studies demonstrate beneficial effects of green tea or green tea extracts, rich in EGCG on weight management, glucose control and cardiovascular risk factors. The optimal dose has not yet been established. The current body of evidence in humans warrants further attention. In particular, well-controlled long-term human studies would help to fully understand the protective effects of green tea catechins on parameters related to the MetS.

Authors+Show Affiliations

DSM Nutritional Products Ltd., New Business Development, Human Nutrition and Health, P.O. Box 2676, Bldg. 241/965, 4002 Basel, CH, Switzerland. frank.thielecke@email.deNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19147161

Citation

Thielecke, Frank, and Michael Boschmann. "The Potential Role of Green Tea Catechins in the Prevention of the Metabolic Syndrome - a Review." Phytochemistry, vol. 70, no. 1, 2009, pp. 11-24.
Thielecke F, Boschmann M. The potential role of green tea catechins in the prevention of the metabolic syndrome - a review. Phytochemistry. 2009;70(1):11-24.
Thielecke, F., & Boschmann, M. (2009). The potential role of green tea catechins in the prevention of the metabolic syndrome - a review. Phytochemistry, 70(1), 11-24. https://doi.org/10.1016/j.phytochem.2008.11.011
Thielecke F, Boschmann M. The Potential Role of Green Tea Catechins in the Prevention of the Metabolic Syndrome - a Review. Phytochemistry. 2009;70(1):11-24. PubMed PMID: 19147161.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The potential role of green tea catechins in the prevention of the metabolic syndrome - a review. AU - Thielecke,Frank, AU - Boschmann,Michael, Y1 - 2009/01/13/ PY - 2008/01/17/received PY - 2008/11/20/revised PY - 2008/11/20/accepted PY - 2009/1/17/entrez PY - 2009/1/17/pubmed PY - 2009/5/14/medline SP - 11 EP - 24 JF - Phytochemistry JO - Phytochemistry VL - 70 IS - 1 N2 - The metabolic syndrome (MetS) represents an emerging health burden for governments and health care providers. Particularly relevant for prevention and early management of MetS are lifestyle conditions including physical activity and the diet. It has been shown that green tea, when consumed on a daily basis, supports health. Many of the beneficial effects of green tea are related to its catechin, particularly (-)-epigallocatechin-3-gallate (EGCG), content. There is conclusive evidence from in vitro and animal studies which provide the concepts for underlying functional mechanisms of green tea catechins and their biological actions. An increasing number of human studies have explored the effects of green tea catechins on the major MetS conditions such as obesity, type-2 diabetes and cardiovascular risk factors. This article provides a comprehensive overview of the human studies addressing the potential benefits of green tea catechins on the MetS. The number of human studies in this field is still limited. However, the majority of human epidemiological and intervention studies demonstrate beneficial effects of green tea or green tea extracts, rich in EGCG on weight management, glucose control and cardiovascular risk factors. The optimal dose has not yet been established. The current body of evidence in humans warrants further attention. In particular, well-controlled long-term human studies would help to fully understand the protective effects of green tea catechins on parameters related to the MetS. SN - 0031-9422 UR - https://www.unboundmedicine.com/medline/citation/19147161/The_potential_role_of_green_tea_catechins_in_the_prevention_of_the_metabolic_syndrome___a_review_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-9422(08)00588-8 DB - PRIME DP - Unbound Medicine ER -
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