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Recent advances in obesity pharmacotherapy.
Curr Clin Pharmacol. 2009 Jan; 4(1):53-61.CC

Abstract

Obesity is considered a worldwide epidemic. Weight reduction by means of lifestyle changes is difficult to achieve, and pharmacotherapy is frequently needed. Although all currently approved anti-obesity agents have proven to be effective to achieve some degree of weight reduction and improve cardiometabolic risk factors, different compounds differ in their mechanism of action and safety profile. However, it is still difficult to achieve and maintain therapeutic objectives along time. The aim of the present article is to summarize the main characteristics of available anti-obesity agents and to explore novel agents that may provide significant clinical benefits in the future.

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Authors+Show Affiliations

Mayer MA
Faculty of Pharmacy and Biochemistry, University of Buenos Aires, Junín, 956, (C1113AAD) Buenos Aires, Argentina. marcos.mayer@gmail.com
Höcht C
No affiliation info available
Puyó A
No affiliation info available
Taira CA
No affiliation info available

MeSH

AnimalsAnti-Obesity AgentsCardiovascular DiseasesCyclobutanesHumansLactonesObesityOrlistatPiperidinesPyrazolesRimonabant

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19149502

Citation

Mayer, Marcos A., et al. "Recent Advances in Obesity Pharmacotherapy." Current Clinical Pharmacology, vol. 4, no. 1, 2009, pp. 53-61.
Mayer MA, Höcht C, Puyó A, et al. Recent advances in obesity pharmacotherapy. Curr Clin Pharmacol. 2009;4(1):53-61.
Mayer, M. A., Höcht, C., Puyó, A., & Taira, C. A. (2009). Recent advances in obesity pharmacotherapy. Current Clinical Pharmacology, 4(1), 53-61.
Mayer MA, et al. Recent Advances in Obesity Pharmacotherapy. Curr Clin Pharmacol. 2009;4(1):53-61. PubMed PMID: 19149502.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Recent advances in obesity pharmacotherapy. AU - Mayer,Marcos A, AU - Höcht,Christian, AU - Puyó,Ana, AU - Taira,Carlos A, PY - 2009/1/20/entrez PY - 2009/1/20/pubmed PY - 2009/5/19/medline SP - 53 EP - 61 JF - Current clinical pharmacology JO - Curr Clin Pharmacol VL - 4 IS - 1 N2 - Obesity is considered a worldwide epidemic. Weight reduction by means of lifestyle changes is difficult to achieve, and pharmacotherapy is frequently needed. Although all currently approved anti-obesity agents have proven to be effective to achieve some degree of weight reduction and improve cardiometabolic risk factors, different compounds differ in their mechanism of action and safety profile. However, it is still difficult to achieve and maintain therapeutic objectives along time. The aim of the present article is to summarize the main characteristics of available anti-obesity agents and to explore novel agents that may provide significant clinical benefits in the future. SN - 1574-8847 UR - https://www.unboundmedicine.com/medline/citation/19149502/Recent_advances_in_obesity_pharmacotherapy_ L2 - https://www.ingentaconnect.com/openurl?genre=article&issn=1574-8847&volume=4&issue=1&spage=53&aulast=Mayer DB - PRIME DP - Unbound Medicine ER -