Tags

Type your tag names separated by a space and hit enter

Ethnic differences in cardiometabolic risk profile in an overweight/obese paediatric cohort in the Netherlands: a cross-sectional study.
Cardiovasc Diabetol. 2009 Jan 19; 8:2.CD

Abstract

BACKGROUND

Differences in prevalence of cardiometabolic risk factors between different ethnic groups are largely unknown. We determined the variation in cardiometabolic risk profile according to ethnicity in a cohort overweight/obese Dutch children.

METHODS

An oral glucose tolerance test was performed in 516 overweight/obese Dutch children of multi-ethnic origin, attending an obesity out-patient clinic of an urban general hospital (mean age 10.6 +/- 3.2; 55.2% boys). Anthropometric parameters and blood samples were collected, and the prevalence of (components of) the metabolic syndrome (MetS) and insulin resistance were determined in each ethnic group.

RESULTS

Major ethnic groups were Dutch native (18.4%), Turkish (28.1%), and Moroccan (25.8%). The remaining group (27.7%) consisted of children with other ethnicities. Turkish children had the highest mean standardized BMI compared to Dutch native children (P < 0.05). As compared to Moroccan children, they had a higher prevalence of MetS (22.8% vs. 12.8%), low HDL-cholesterol (37.9% vs. 25.8%), hypertension (29.7% vs. 18.0%) and insulin resistance (54.9% vs. 37.4%, all P < 0.05). Although Turkish children also had higher prevalences of forementioned risk factors than Dutch native children, these differences were not statistically significant. Insulin resistance was associated with MetS in the Turkish and Moroccan subgroup (OR 6.6; 95%CI, 2.4-18.3 and OR 7.0; 95%CI, 2.1-23.1, respectively).

CONCLUSION

In a Dutch cohort of overweight/obese children, Turkish children showed significantly higher prevalences of cardiometabolic risk factors relative to their peers of Moroccan descent. The prospective value of these findings needs to be established as this may warrant the need for differential ethnic-specific preventive measures.

Authors+Show Affiliations

Department of Paediatrics, Slotervaart Hospital, Amsterdam, the Netherlands. ma.vanvliet@vumc.nlNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19152682

Citation

van Vliet, Mariska, et al. "Ethnic Differences in Cardiometabolic Risk Profile in an Overweight/obese Paediatric Cohort in the Netherlands: a Cross-sectional Study." Cardiovascular Diabetology, vol. 8, 2009, p. 2.
van Vliet M, von Rosenstiel IA, Schindhelm RK, et al. Ethnic differences in cardiometabolic risk profile in an overweight/obese paediatric cohort in the Netherlands: a cross-sectional study. Cardiovasc Diabetol. 2009;8:2.
van Vliet, M., von Rosenstiel, I. A., Schindhelm, R. K., Brandjes, D. P., Beijnen, J. H., & Diamant, M. (2009). Ethnic differences in cardiometabolic risk profile in an overweight/obese paediatric cohort in the Netherlands: a cross-sectional study. Cardiovascular Diabetology, 8, 2. https://doi.org/10.1186/1475-2840-8-2
van Vliet M, et al. Ethnic Differences in Cardiometabolic Risk Profile in an Overweight/obese Paediatric Cohort in the Netherlands: a Cross-sectional Study. Cardiovasc Diabetol. 2009 Jan 19;8:2. PubMed PMID: 19152682.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ethnic differences in cardiometabolic risk profile in an overweight/obese paediatric cohort in the Netherlands: a cross-sectional study. AU - van Vliet,Mariska, AU - von Rosenstiel,Inès A, AU - Schindhelm,Roger K, AU - Brandjes,Desiderius P M, AU - Beijnen,Jos H, AU - Diamant,Michaela, Y1 - 2009/01/19/ PY - 2008/11/17/received PY - 2009/01/19/accepted PY - 2009/1/21/entrez PY - 2009/1/21/pubmed PY - 2009/3/19/medline SP - 2 EP - 2 JF - Cardiovascular diabetology JO - Cardiovasc Diabetol VL - 8 N2 - BACKGROUND: Differences in prevalence of cardiometabolic risk factors between different ethnic groups are largely unknown. We determined the variation in cardiometabolic risk profile according to ethnicity in a cohort overweight/obese Dutch children. METHODS: An oral glucose tolerance test was performed in 516 overweight/obese Dutch children of multi-ethnic origin, attending an obesity out-patient clinic of an urban general hospital (mean age 10.6 +/- 3.2; 55.2% boys). Anthropometric parameters and blood samples were collected, and the prevalence of (components of) the metabolic syndrome (MetS) and insulin resistance were determined in each ethnic group. RESULTS: Major ethnic groups were Dutch native (18.4%), Turkish (28.1%), and Moroccan (25.8%). The remaining group (27.7%) consisted of children with other ethnicities. Turkish children had the highest mean standardized BMI compared to Dutch native children (P < 0.05). As compared to Moroccan children, they had a higher prevalence of MetS (22.8% vs. 12.8%), low HDL-cholesterol (37.9% vs. 25.8%), hypertension (29.7% vs. 18.0%) and insulin resistance (54.9% vs. 37.4%, all P < 0.05). Although Turkish children also had higher prevalences of forementioned risk factors than Dutch native children, these differences were not statistically significant. Insulin resistance was associated with MetS in the Turkish and Moroccan subgroup (OR 6.6; 95%CI, 2.4-18.3 and OR 7.0; 95%CI, 2.1-23.1, respectively). CONCLUSION: In a Dutch cohort of overweight/obese children, Turkish children showed significantly higher prevalences of cardiometabolic risk factors relative to their peers of Moroccan descent. The prospective value of these findings needs to be established as this may warrant the need for differential ethnic-specific preventive measures. SN - 1475-2840 UR - https://www.unboundmedicine.com/medline/citation/19152682/Ethnic_differences_in_cardiometabolic_risk_profile_in_an_overweight/obese_paediatric_cohort_in_the_Netherlands:_a_cross_sectional_study_ L2 - https://cardiab.biomedcentral.com/articles/10.1186/1475-2840-8-2 DB - PRIME DP - Unbound Medicine ER -