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Cardiovascular disease prevalence, associated risk factors, and plasma adiponectin levels among Filipino American women.
Ethn Dis. 2008 Autumn; 18(4):458-63.ED

Abstract

OBJECTIVES

This cross-sectional study was designed to examine the association between adiponectin and cardiovascular disease (CVD) among an understudied ethnic group of Filipino American women.

METHODS

We recruited 266 Filipino women aged 40-86 years from the University of California, San Diego Filipino Women's Health Study (1995-1999). Plasma adiponectin was extracted from archive blood samples and measured by radioimmunoassay. CVD was defined as coronary heart disease, angina, myocardial infarction, or stroke by history, electrocardiogram (Minnesota coding), or Rose questionnaire.

RESULTS

CVD prevalence among Filipinas was 20.7% (n=55), of which 85.5% were newly diagnosed. Filipinas with versus without CVD had more antihypertensive medication use (44.4% vs 26.7%), more parental history of myocardial infarction (38.2% vs 21.8%), higher proinsulin levels (13.2 vs 11.0 pmol/L), lower adiponectin levels (5.09 vs 6.15 microg/mL), and higher prevalences of the metabolic syndrome (34.6% vs 28.0%) and microalbuminuria (24.0% vs 12.2%). Adiponectin (adjusted OR .46, 95% CI .23-.89, P=.021) was independently associated with CVD in multivariate analysis that adjusted for age, exercise, family history, diabetes, hypertension, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and microalbuminuria.

CONCLUSIONS

Independent of known risk factors, adiponectin was associated with CVD among Filipinas. This finding suggests that adiponectin may be a useful CVD indicator among this ethnic population.

Authors+Show Affiliations

Graduate School of Public Health, San Diego State University, San Diego, California, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

19157250

Citation

Magno, Cheryl P., et al. "Cardiovascular Disease Prevalence, Associated Risk Factors, and Plasma Adiponectin Levels Among Filipino American Women." Ethnicity & Disease, vol. 18, no. 4, 2008, pp. 458-63.
Magno CP, Araneta MR, Macera CA, et al. Cardiovascular disease prevalence, associated risk factors, and plasma adiponectin levels among Filipino American women. Ethn Dis. 2008;18(4):458-63.
Magno, C. P., Araneta, M. R., Macera, C. A., & Anderson, G. W. (2008). Cardiovascular disease prevalence, associated risk factors, and plasma adiponectin levels among Filipino American women. Ethnicity & Disease, 18(4), 458-63.
Magno CP, et al. Cardiovascular Disease Prevalence, Associated Risk Factors, and Plasma Adiponectin Levels Among Filipino American Women. Ethn Dis. 2008;18(4):458-63. PubMed PMID: 19157250.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cardiovascular disease prevalence, associated risk factors, and plasma adiponectin levels among Filipino American women. AU - Magno,Cheryl P, AU - Araneta,Maria Rosario G, AU - Macera,Caroline A, AU - Anderson,Gwen W, PY - 2009/1/23/entrez PY - 2009/1/23/pubmed PY - 2009/2/14/medline SP - 458 EP - 63 JF - Ethnicity & disease JO - Ethn Dis VL - 18 IS - 4 N2 - OBJECTIVES: This cross-sectional study was designed to examine the association between adiponectin and cardiovascular disease (CVD) among an understudied ethnic group of Filipino American women. METHODS: We recruited 266 Filipino women aged 40-86 years from the University of California, San Diego Filipino Women's Health Study (1995-1999). Plasma adiponectin was extracted from archive blood samples and measured by radioimmunoassay. CVD was defined as coronary heart disease, angina, myocardial infarction, or stroke by history, electrocardiogram (Minnesota coding), or Rose questionnaire. RESULTS: CVD prevalence among Filipinas was 20.7% (n=55), of which 85.5% were newly diagnosed. Filipinas with versus without CVD had more antihypertensive medication use (44.4% vs 26.7%), more parental history of myocardial infarction (38.2% vs 21.8%), higher proinsulin levels (13.2 vs 11.0 pmol/L), lower adiponectin levels (5.09 vs 6.15 microg/mL), and higher prevalences of the metabolic syndrome (34.6% vs 28.0%) and microalbuminuria (24.0% vs 12.2%). Adiponectin (adjusted OR .46, 95% CI .23-.89, P=.021) was independently associated with CVD in multivariate analysis that adjusted for age, exercise, family history, diabetes, hypertension, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and microalbuminuria. CONCLUSIONS: Independent of known risk factors, adiponectin was associated with CVD among Filipinas. This finding suggests that adiponectin may be a useful CVD indicator among this ethnic population. SN - 1049-510X UR - https://www.unboundmedicine.com/medline/citation/19157250/Cardiovascular_disease_prevalence_associated_risk_factors_and_plasma_adiponectin_levels_among_Filipino_American_women_ L2 - https://medlineplus.gov/asianamericanhealth.html DB - PRIME DP - Unbound Medicine ER -