Tags

Type your tag names separated by a space and hit enter

Prevalence of diabetic retinopathy in rural China: the Handan Eye Study.
Ophthalmology 2009; 116(3):461-7O

Abstract

PURPOSE

To describe the age- and gender-specific prevalence, characteristics, and severity of diabetic retinopathy (DR) in a rural population in northern China.

DESIGN

A population-based cross-sectional study.

PARTICIPANTS

A total of 6830 Han Chinese aged 30 years and older from 13 villages of Yongnian County, Handan City, Hebei Province, China.

METHODS

All participants underwent a standardized interview, a comprehensive eye examination, and fasting blood glucose testing according to the American Diabetes Association diagnostic criteria (fasting plasma glucose >or=7.0 mmol/l). Retinal photographs obtained after pupil dilation were graded for the presence and severity of DR according to the modified Early Treatment Diabetic Retinopathy Study classification system.

MAIN OUTCOME MEASURES

Any DR, retinopathy grades, macular edema, or vision-threatening retinopathy.

RESULTS

Of the 6830 eligible individuals participating in the study, 5597 (81.9%) had fasting blood glucose results available. Of these, 387 participants (6.9%) were diagnosed with diabetes mellitus, including 247 subjects with new diabetes mellitus (NDM) and 140 subjects with known diabetes mellitus (KDM). For these, gradable photographs were available for 368 subjects (95.1%). The overall prevalence of DR was 43.1% (95% confidence interval, 38.1-48.4) and was higher in persons with KDM (65.2%) than NDM (33.5%). The prevalence of proliferative DR, macular edema, and vision-threatening retinopathy was 1.6%, 5.2%, and 6.3%, respectively, with 12.1% with KDM having untreated vision-threatening DR. No age- or gender-related differences were present. The prevalence of DR was strongly related to duration of disease.

CONCLUSIONS

Our study reports a high prevalence of DR among adults 30 years and older with diabetes in rural China. On the basis of estimates obtained from our study, we projected that in rural China, 21.1 million persons aged 30+ years have diabetes and 9.2 million have DR, including 1.3 million with vision-threatening DR. There is a pressing need for appropriate screening and management of diabetes and its complications in rural China.

Authors+Show Affiliations

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Lab, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19168222

Citation

Wang, Feng Hua, et al. "Prevalence of Diabetic Retinopathy in Rural China: the Handan Eye Study." Ophthalmology, vol. 116, no. 3, 2009, pp. 461-7.
Wang FH, Liang YB, Zhang F, et al. Prevalence of diabetic retinopathy in rural China: the Handan Eye Study. Ophthalmology. 2009;116(3):461-7.
Wang, F. H., Liang, Y. B., Zhang, F., Wang, J. J., Wei, W. B., Tao, Q. S., ... Wong, T. Y. (2009). Prevalence of diabetic retinopathy in rural China: the Handan Eye Study. Ophthalmology, 116(3), pp. 461-7. doi:10.1016/j.ophtha.2008.10.003.
Wang FH, et al. Prevalence of Diabetic Retinopathy in Rural China: the Handan Eye Study. Ophthalmology. 2009;116(3):461-7. PubMed PMID: 19168222.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of diabetic retinopathy in rural China: the Handan Eye Study. AU - Wang,Feng Hua, AU - Liang,Yuan Bo, AU - Zhang,Feng, AU - Wang,Jie Jin, AU - Wei,Wen Bin, AU - Tao,Qiu Shan, AU - Sun,Lan Ping, AU - Friedman,David S, AU - Wang,Ning Li, AU - Wong,Tien Yin, Y1 - 2009/01/24/ PY - 2008/06/16/received PY - 2008/10/04/revised PY - 2008/10/06/accepted PY - 2009/1/27/entrez PY - 2009/1/27/pubmed PY - 2009/3/21/medline SP - 461 EP - 7 JF - Ophthalmology JO - Ophthalmology VL - 116 IS - 3 N2 - PURPOSE: To describe the age- and gender-specific prevalence, characteristics, and severity of diabetic retinopathy (DR) in a rural population in northern China. DESIGN: A population-based cross-sectional study. PARTICIPANTS: A total of 6830 Han Chinese aged 30 years and older from 13 villages of Yongnian County, Handan City, Hebei Province, China. METHODS: All participants underwent a standardized interview, a comprehensive eye examination, and fasting blood glucose testing according to the American Diabetes Association diagnostic criteria (fasting plasma glucose >or=7.0 mmol/l). Retinal photographs obtained after pupil dilation were graded for the presence and severity of DR according to the modified Early Treatment Diabetic Retinopathy Study classification system. MAIN OUTCOME MEASURES: Any DR, retinopathy grades, macular edema, or vision-threatening retinopathy. RESULTS: Of the 6830 eligible individuals participating in the study, 5597 (81.9%) had fasting blood glucose results available. Of these, 387 participants (6.9%) were diagnosed with diabetes mellitus, including 247 subjects with new diabetes mellitus (NDM) and 140 subjects with known diabetes mellitus (KDM). For these, gradable photographs were available for 368 subjects (95.1%). The overall prevalence of DR was 43.1% (95% confidence interval, 38.1-48.4) and was higher in persons with KDM (65.2%) than NDM (33.5%). The prevalence of proliferative DR, macular edema, and vision-threatening retinopathy was 1.6%, 5.2%, and 6.3%, respectively, with 12.1% with KDM having untreated vision-threatening DR. No age- or gender-related differences were present. The prevalence of DR was strongly related to duration of disease. CONCLUSIONS: Our study reports a high prevalence of DR among adults 30 years and older with diabetes in rural China. On the basis of estimates obtained from our study, we projected that in rural China, 21.1 million persons aged 30+ years have diabetes and 9.2 million have DR, including 1.3 million with vision-threatening DR. There is a pressing need for appropriate screening and management of diabetes and its complications in rural China. SN - 1549-4713 UR - https://www.unboundmedicine.com/medline/citation/19168222/Prevalence_of_diabetic_retinopathy_in_rural_China:_the_Handan_Eye_Study_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(08)01023-3 DB - PRIME DP - Unbound Medicine ER -