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Screening of antioxidant properties of seven Umbelliferae fruits from Iran.
Pak J Pharm Sci. 2009 Jan; 22(1):30-5.PJ

Abstract

Antioxidative activities (IC(50)) of ethanol extracts from seven Umbelliferae fruits (Bunium persicum, Coriandrum sativum, Cuminum cyminum, Foeniculum vulgare, Heracleum persicum, Pimpinella anisum and Trachyspermum copticum) have been studied by the DPPH (2,2'-diphenyl-1-picrylhydrazyl) radical scavenging test. All the studied extracts showed antioxidant capability and P. anisum extract exhibited the strongest activity. The scavenging activity of the extracts in decreasing order was: P. anisum> T. copticum> C. cyminum> F. vulgare > or = B. persicum > or = C. sativum> H. persicum. The extracts were also investigated regarding their total flavonoid contents by the AlCl3 technique. The decreasing order of the flavonoid content of the extracts was: C. cyminum > T. copticum> P. anisum > or = H. persicum > or = B. persicum > or = F. vulgare > or = C. sativum. However, a favorable correlation was not found between the antioxidant activity and the total flavonoid content of the extracts. As well, the most active extract (i.e. P. anisum) was partitioned with n-hexane, chloroform and ethyl acetate to yield three organic fractions together with the remaining aqueous fraction. The antioxidative activities (IP%) and flavonoid contents of the fractions were also determined. The ethyl acetate fraction exhibited the highest activity and content. A positive correlation was found between the antioxidant potency and flavonoid content of the fractions.

Authors+Show Affiliations

Department of Pharmacognosy, Shahid Beheshti University, Tehran, Iran. bnickavar@yahoo.comNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

19168417

Citation

Nickavar, Bahman, and Farideh Al-Sadat Abolhasani. "Screening of Antioxidant Properties of Seven Umbelliferae Fruits From Iran." Pakistan Journal of Pharmaceutical Sciences, vol. 22, no. 1, 2009, pp. 30-5.
Nickavar B, Abolhasani FA. Screening of antioxidant properties of seven Umbelliferae fruits from Iran. Pak J Pharm Sci. 2009;22(1):30-5.
Nickavar, B., & Abolhasani, F. A. (2009). Screening of antioxidant properties of seven Umbelliferae fruits from Iran. Pakistan Journal of Pharmaceutical Sciences, 22(1), 30-5.
Nickavar B, Abolhasani FA. Screening of Antioxidant Properties of Seven Umbelliferae Fruits From Iran. Pak J Pharm Sci. 2009;22(1):30-5. PubMed PMID: 19168417.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Screening of antioxidant properties of seven Umbelliferae fruits from Iran. AU - Nickavar,Bahman, AU - Abolhasani,Farideh Al-Sadat, PY - 2009/1/27/entrez PY - 2009/1/27/pubmed PY - 2009/3/13/medline SP - 30 EP - 5 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 22 IS - 1 N2 - Antioxidative activities (IC(50)) of ethanol extracts from seven Umbelliferae fruits (Bunium persicum, Coriandrum sativum, Cuminum cyminum, Foeniculum vulgare, Heracleum persicum, Pimpinella anisum and Trachyspermum copticum) have been studied by the DPPH (2,2'-diphenyl-1-picrylhydrazyl) radical scavenging test. All the studied extracts showed antioxidant capability and P. anisum extract exhibited the strongest activity. The scavenging activity of the extracts in decreasing order was: P. anisum> T. copticum> C. cyminum> F. vulgare > or = B. persicum > or = C. sativum> H. persicum. The extracts were also investigated regarding their total flavonoid contents by the AlCl3 technique. The decreasing order of the flavonoid content of the extracts was: C. cyminum > T. copticum> P. anisum > or = H. persicum > or = B. persicum > or = F. vulgare > or = C. sativum. However, a favorable correlation was not found between the antioxidant activity and the total flavonoid content of the extracts. As well, the most active extract (i.e. P. anisum) was partitioned with n-hexane, chloroform and ethyl acetate to yield three organic fractions together with the remaining aqueous fraction. The antioxidative activities (IP%) and flavonoid contents of the fractions were also determined. The ethyl acetate fraction exhibited the highest activity and content. A positive correlation was found between the antioxidant potency and flavonoid content of the fractions. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/19168417/Screening_of_antioxidant_properties_of_seven_Umbelliferae_fruits_from_Iran_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -