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[Systemic proliferative angioendotheliomatosis: a cutaneous manifestation of malignant B-cell lymphomas. Histologic and immunohistologic studies of two cases].
Hautarzt 1991; 42(6):384-90H

Abstract

Angioendotheliomatosis proliferans systemisata (AEPS) is a rare disease entity characterized by a predominantly intravascular proliferation of tumour cells. Two forms of AEPS are differentiated: a very rare, benign and self-limiting form, which is endothelial in origin, and a more common, malignant form, which is an angiotropic intravascular malignant B-cell lymphoma. Histological and immunohistological investigations of the malignant form of AEPS are presented: In a 69-year-old woman cutaneous lesions appeared 5 months before the diagnosis of B-immunoblastic lymphoma. In a 57-year-old woman lesions were observed simultaneously with the relapse of a high-grade malignant B-cell lymphoma. Immunohistological identification of the proliferating cell type made diagnosis of intravascular B-cell lymphoma possible in paraffin-embedded biopsies.

Authors+Show Affiliations

Kutzner H
Dermatohistologisches Labor der Gemeinschaftspraxis, Friedrichshafen.
Englert W
No affiliation info available
Hellenbroich D
No affiliation info available
Embacher G
No affiliation info available
Kutzner U
No affiliation info available
Schröder J
No affiliation info available

MeSH

AgedBiomarkers, TumorBiopsyBreast NeoplasmsEndothelium, VascularFemaleHemangioendotheliomaHumansImmunoenzyme TechniquesLymphoma, B-CellLymphoma, Large-Cell, ImmunoblasticMiddle AgedNeoplasms, Multiple PrimaryParaneoplastic SyndromesSkinSkin NeoplasmsTongue Neoplasms

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

1917462

Citation

Kutzner, H, et al. "[Systemic Proliferative Angioendotheliomatosis: a Cutaneous Manifestation of Malignant B-cell Lymphomas. Histologic and Immunohistologic Studies of Two Cases]." Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, vol. 42, no. 6, 1991, pp. 384-90.
Kutzner H, Englert W, Hellenbroich D, et al. [Systemic proliferative angioendotheliomatosis: a cutaneous manifestation of malignant B-cell lymphomas. Histologic and immunohistologic studies of two cases]. Hautarzt. 1991;42(6):384-90.
Kutzner, H., Englert, W., Hellenbroich, D., Embacher, G., Kutzner, U., & Schröder, J. (1991). [Systemic proliferative angioendotheliomatosis: a cutaneous manifestation of malignant B-cell lymphomas. Histologic and immunohistologic studies of two cases]. Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete, 42(6), pp. 384-90.
Kutzner H, et al. [Systemic Proliferative Angioendotheliomatosis: a Cutaneous Manifestation of Malignant B-cell Lymphomas. Histologic and Immunohistologic Studies of Two Cases]. Hautarzt. 1991;42(6):384-90. PubMed PMID: 1917462.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Systemic proliferative angioendotheliomatosis: a cutaneous manifestation of malignant B-cell lymphomas. Histologic and immunohistologic studies of two cases]. AU - Kutzner,H, AU - Englert,W, AU - Hellenbroich,D, AU - Embacher,G, AU - Kutzner,U, AU - Schröder,J, PY - 1991/6/1/pubmed PY - 1991/6/1/medline PY - 1991/6/1/entrez SP - 384 EP - 90 JF - Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete JO - Hautarzt VL - 42 IS - 6 N2 - Angioendotheliomatosis proliferans systemisata (AEPS) is a rare disease entity characterized by a predominantly intravascular proliferation of tumour cells. Two forms of AEPS are differentiated: a very rare, benign and self-limiting form, which is endothelial in origin, and a more common, malignant form, which is an angiotropic intravascular malignant B-cell lymphoma. Histological and immunohistological investigations of the malignant form of AEPS are presented: In a 69-year-old woman cutaneous lesions appeared 5 months before the diagnosis of B-immunoblastic lymphoma. In a 57-year-old woman lesions were observed simultaneously with the relapse of a high-grade malignant B-cell lymphoma. Immunohistological identification of the proliferating cell type made diagnosis of intravascular B-cell lymphoma possible in paraffin-embedded biopsies. SN - 0017-8470 UR - https://www.unboundmedicine.com/medline/citation/1917462/[Systemic_proliferative_angioendotheliomatosis:_a_cutaneous_manifestation_of_malignant_B_cell_lymphomas__Histologic_and_immunohistologic_studies_of_two_cases]_ L2 - http://www.diseaseinfosearch.org/result/2041 DB - PRIME DP - Unbound Medicine ER -