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Occurrence and detection of iron-deficiency anemia in infants and toddlers.
Clin Lab Sci. 2008 Fall; 21(4):225-31.CL

Abstract

Infants and toddlers are particularly vulnerable to developing iron deficiency, which can cause irreversible deficits in neurodevelopment. Children at highest risk include premature and low birth weight infants, those who are fed cow's milk rather than breast milk or formula prior to age one, and those who drink large amounts of cow's milk as toddlers. It is important to detect iron deficiency before it becomes frank anemia through the use of appropriate laboratory tests. Hemoglobin or hematocrit testing, at around age one, has been the usual screening test. These tests, however, do not become abnormally low until frank anemia has developed. Over the past decade, research has shown the assay for reticulocyte hemoglobin content to be a much earlier indicator of iron deficiency. This article provides an overview of the epidemiology, occurrence, and detection of iron deficiency and iron deficiency anemia in young children as well as a comparison of the utility of various laboratory tests.

Authors+Show Affiliations

Department of Clinical Laboratory Science, College of Allied Health Sciences, East Carolina University, Greenville, NC 27858-4353, USA. bambergw@ecu.edu

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19174983

Citation

Bamberg, Richard. "Occurrence and Detection of Iron-deficiency Anemia in Infants and Toddlers." Clinical Laboratory Science : Journal of the American Society for Medical Technology, vol. 21, no. 4, 2008, pp. 225-31.
Bamberg R. Occurrence and detection of iron-deficiency anemia in infants and toddlers. Clin Lab Sci. 2008;21(4):225-31.
Bamberg, R. (2008). Occurrence and detection of iron-deficiency anemia in infants and toddlers. Clinical Laboratory Science : Journal of the American Society for Medical Technology, 21(4), 225-31.
Bamberg R. Occurrence and Detection of Iron-deficiency Anemia in Infants and Toddlers. Clin Lab Sci. 2008;21(4):225-31. PubMed PMID: 19174983.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Occurrence and detection of iron-deficiency anemia in infants and toddlers. A1 - Bamberg,Richard, PY - 2009/1/30/entrez PY - 2009/1/30/pubmed PY - 2009/2/20/medline SP - 225 EP - 31 JF - Clinical laboratory science : journal of the American Society for Medical Technology JO - Clin Lab Sci VL - 21 IS - 4 N2 - Infants and toddlers are particularly vulnerable to developing iron deficiency, which can cause irreversible deficits in neurodevelopment. Children at highest risk include premature and low birth weight infants, those who are fed cow's milk rather than breast milk or formula prior to age one, and those who drink large amounts of cow's milk as toddlers. It is important to detect iron deficiency before it becomes frank anemia through the use of appropriate laboratory tests. Hemoglobin or hematocrit testing, at around age one, has been the usual screening test. These tests, however, do not become abnormally low until frank anemia has developed. Over the past decade, research has shown the assay for reticulocyte hemoglobin content to be a much earlier indicator of iron deficiency. This article provides an overview of the epidemiology, occurrence, and detection of iron deficiency and iron deficiency anemia in young children as well as a comparison of the utility of various laboratory tests. SN - 0894-959X UR - https://www.unboundmedicine.com/medline/citation/19174983/Occurrence_and_detection_of_iron_deficiency_anemia_in_infants_and_toddlers_ L2 - http://www.diseaseinfosearch.org/result/3873 DB - PRIME DP - Unbound Medicine ER -