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Intradialytic versus home-based exercise training in hemodialysis patients: a randomised controlled trial.
BMC Nephrol. 2009 Jan 29; 10:2.BN

Abstract

BACKGROUND

Exercise training in hemodialysis patients improves fitness, physical function, quality of life and markers of cardiovascular disease such as arterial stiffness. The majority of trials investigating this area have used supervised exercise training during dialysis (intradialytic), which may not be feasible for some renal units. The aim of this trial is to compare the effects of supervised intradialytic with unsupervised home-based exercise training on physical function and arterial stiffness.

METHODS AND DESIGN

This is a randomised, controlled clinical trial. A total of 72 hemodialysis patients will be randomised to receive either six months of intradialytic exercise training, home-based exercise training or usual care. Intradialytic patients will undergo three training sessions per week on a cycle ergometer and home-based patients will be provided with a walking program to achieve the same weekly physical activity. Primary outcome measures are six-minute walk distance (6 MWD) and aortic pulse wave velocity (PWV). Secondary outcome measures include augmentation index, peripheral and central blood pressures, physical activity and self-reported health. Measures will be made at baseline, three and six months.

DISCUSSION

The results of this study will help determine the efficacy of home-based exercise training in hemodialysis patients. This may assist in developing exercise guidelines specific for these patients.

TRIAL REGISTRATION

ACTRN12608000247370

Authors+Show Affiliations

School of Human Life Sciences, University of Tasmania, Newnham, Tasmania 7250, Australia. kirsten_koh@rp.sgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19178747

Citation

Koh, Kirsten P., et al. "Intradialytic Versus Home-based Exercise Training in Hemodialysis Patients: a Randomised Controlled Trial." BMC Nephrology, vol. 10, 2009, p. 2.
Koh KP, Fassett RG, Sharman JE, et al. Intradialytic versus home-based exercise training in hemodialysis patients: a randomised controlled trial. BMC Nephrol. 2009;10:2.
Koh, K. P., Fassett, R. G., Sharman, J. E., Coombes, J. S., & Williams, A. D. (2009). Intradialytic versus home-based exercise training in hemodialysis patients: a randomised controlled trial. BMC Nephrology, 10, 2. https://doi.org/10.1186/1471-2369-10-2
Koh KP, et al. Intradialytic Versus Home-based Exercise Training in Hemodialysis Patients: a Randomised Controlled Trial. BMC Nephrol. 2009 Jan 29;10:2. PubMed PMID: 19178747.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intradialytic versus home-based exercise training in hemodialysis patients: a randomised controlled trial. AU - Koh,Kirsten P, AU - Fassett,Robert G, AU - Sharman,James E, AU - Coombes,Jeff S, AU - Williams,Andrew D, Y1 - 2009/01/29/ PY - 2008/12/04/received PY - 2009/01/29/accepted PY - 2009/1/31/entrez PY - 2009/1/31/pubmed PY - 2009/5/9/medline SP - 2 EP - 2 JF - BMC nephrology JO - BMC Nephrol VL - 10 N2 - BACKGROUND: Exercise training in hemodialysis patients improves fitness, physical function, quality of life and markers of cardiovascular disease such as arterial stiffness. The majority of trials investigating this area have used supervised exercise training during dialysis (intradialytic), which may not be feasible for some renal units. The aim of this trial is to compare the effects of supervised intradialytic with unsupervised home-based exercise training on physical function and arterial stiffness. METHODS AND DESIGN: This is a randomised, controlled clinical trial. A total of 72 hemodialysis patients will be randomised to receive either six months of intradialytic exercise training, home-based exercise training or usual care. Intradialytic patients will undergo three training sessions per week on a cycle ergometer and home-based patients will be provided with a walking program to achieve the same weekly physical activity. Primary outcome measures are six-minute walk distance (6 MWD) and aortic pulse wave velocity (PWV). Secondary outcome measures include augmentation index, peripheral and central blood pressures, physical activity and self-reported health. Measures will be made at baseline, three and six months. DISCUSSION: The results of this study will help determine the efficacy of home-based exercise training in hemodialysis patients. This may assist in developing exercise guidelines specific for these patients. TRIAL REGISTRATION: ACTRN12608000247370 SN - 1471-2369 UR - https://www.unboundmedicine.com/medline/citation/19178747/Intradialytic_versus_home_based_exercise_training_in_hemodialysis_patients:_a_randomised_controlled_trial_ L2 - https://www.biomedcentral.com/1471-2369/10/2 DB - PRIME DP - Unbound Medicine ER -