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Postoperative antibiotic care after functional endoscopic sinus surgery.
Am J Rhinol. 2008 Nov-Dec; 22(6):608-12.AJ

Abstract

BACKGROUND

Antibiotics are used routinely in the postoperative care of functional endoscopic sinus surgery (FESS), but their efficacy has not been well evaluated.

METHODS

Patients with chronic rhinosinusitis who underwent FESS were enrolled in this study. They were randomly divided into two groups: a study group and a control group. In the study group, patients took amoxicillin/clavulante for 3 weeks after FESS. In the control group, no antibiotic was given after FESS. Before FESS, all patients filled out a symptom questionnaire and received nasal endoscopy. Swab specimens were taken from the middle meati for bacterial cultures. These procedures were done again 3 weeks after FESS.

RESULTS

Seventy-one patients completed the study. Thirty-one patients were in the study group, and 40 patients were in the control group. The symptom scores significantly decreased after surgery in both groups, but bacteria identified before and after FESS were statistically different in both groups. There were no differences in the symptom and endoscopic scores, rates of bacterial culture, and drug sensitivity to amoxicillin/clavulante between the two groups after FESS.

CONCLUSION

This study showed that postoperative care with amoxicillin/clavulante did not improve the short-term outcome of FESS on chronic rhinosinusitis or decrease bacterial growth 3weeks after FESS, although the long-term influence was not evaluated in this study.

Authors+Show Affiliations

Department of Otolaryngology, Taichung Veterans General Hospital, Taichung, Taiwan. rsjiang@vghtc.gov.twNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19178799

Citation

Jiang, Rong-San, et al. "Postoperative Antibiotic Care After Functional Endoscopic Sinus Surgery." American Journal of Rhinology, vol. 22, no. 6, 2008, pp. 608-12.
Jiang RS, Liang KL, Yang KY, et al. Postoperative antibiotic care after functional endoscopic sinus surgery. Am J Rhinol. 2008;22(6):608-12.
Jiang, R. S., Liang, K. L., Yang, K. Y., Shiao, J. Y., Su, M. C., Hsin, C. H., & Lin, J. F. (2008). Postoperative antibiotic care after functional endoscopic sinus surgery. American Journal of Rhinology, 22(6), 608-12. https://doi.org/10.2500/ajr.2008.22.3241
Jiang RS, et al. Postoperative Antibiotic Care After Functional Endoscopic Sinus Surgery. Am J Rhinol. 2008 Nov-Dec;22(6):608-12. PubMed PMID: 19178799.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postoperative antibiotic care after functional endoscopic sinus surgery. AU - Jiang,Rong-San, AU - Liang,Kai-Li, AU - Yang,Kung-Yaun, AU - Shiao,Jiun-Yih, AU - Su,Mao-Chang, AU - Hsin,Chung-Han, AU - Lin,Jen-Fu, PY - 2009/1/31/entrez PY - 2009/1/31/pubmed PY - 2009/3/24/medline SP - 608 EP - 12 JF - American journal of rhinology JO - Am J Rhinol VL - 22 IS - 6 N2 - BACKGROUND: Antibiotics are used routinely in the postoperative care of functional endoscopic sinus surgery (FESS), but their efficacy has not been well evaluated. METHODS: Patients with chronic rhinosinusitis who underwent FESS were enrolled in this study. They were randomly divided into two groups: a study group and a control group. In the study group, patients took amoxicillin/clavulante for 3 weeks after FESS. In the control group, no antibiotic was given after FESS. Before FESS, all patients filled out a symptom questionnaire and received nasal endoscopy. Swab specimens were taken from the middle meati for bacterial cultures. These procedures were done again 3 weeks after FESS. RESULTS: Seventy-one patients completed the study. Thirty-one patients were in the study group, and 40 patients were in the control group. The symptom scores significantly decreased after surgery in both groups, but bacteria identified before and after FESS were statistically different in both groups. There were no differences in the symptom and endoscopic scores, rates of bacterial culture, and drug sensitivity to amoxicillin/clavulante between the two groups after FESS. CONCLUSION: This study showed that postoperative care with amoxicillin/clavulante did not improve the short-term outcome of FESS on chronic rhinosinusitis or decrease bacterial growth 3weeks after FESS, although the long-term influence was not evaluated in this study. SN - 1050-6586 UR - https://www.unboundmedicine.com/medline/citation/19178799/Postoperative_antibiotic_care_after_functional_endoscopic_sinus_surgery_ L2 - https://medlineplus.gov/endoscopy.html DB - PRIME DP - Unbound Medicine ER -