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Atypical depression is associated with suicide attempt in bipolar disorder.
Acta Psychiatr Scand. 2009 Jul; 120(1):30-6.AP

Abstract

OBJECTIVE

There is a dearth of research focusing on factors associated with suicide attempts. High rates of atypical depression have been reported in studies including unipolar and bipolar II patients. In this study, the association between suicide attempt and atypical depression, in addition to other major risk factors, was evaluated in 390 bipolar I and II out-patients.

METHOD

Variables were defined according to DSM-IV criteria, and assessed with a Structured Interview for DSM-IV (axis I and II). History of suicide attempt was obtained through interviews with patients and relatives. Attempters and non-attempters were compared using univariate and multivariate analysis.

RESULTS

Attempters showed significantly higher rates of atypical depression, family history of completed suicide, depression at index episode and cluster B personality disorder.

CONCLUSION

Our results highlight the relevance of atypical depression in bipolar disorder. A more accurate identification of potential attempters may contribute to the development of effective preventive treatment strategies.

Links

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Authors+Show Affiliations

Sánchez-Gistau V
Bipolar Disorders Program, Institute of Clinical Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBER-SAM, Barcelona, Catalonia, Spain.
Colom F
No affiliation info available
Mané A
No affiliation info available
Romero S
No affiliation info available
Sugranyes G
No affiliation info available
Vieta E
No affiliation info available

MeSH

AdultBipolar DisorderComorbidityConfidence IntervalsDepressive DisorderFemaleGenetic Predisposition to DiseaseHumansInterview, PsychologicalLogistic ModelsMaleMiddle AgedOdds RatioPersonality DisordersRisk FactorsSpainSuicide, Attempted

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19183125

Citation

Sánchez-Gistau, V, et al. "Atypical Depression Is Associated With Suicide Attempt in Bipolar Disorder." Acta Psychiatrica Scandinavica, vol. 120, no. 1, 2009, pp. 30-6.
Sánchez-Gistau V, Colom F, Mané A, et al. Atypical depression is associated with suicide attempt in bipolar disorder. Acta Psychiatr Scand. 2009;120(1):30-6.
Sánchez-Gistau, V., Colom, F., Mané, A., Romero, S., Sugranyes, G., & Vieta, E. (2009). Atypical depression is associated with suicide attempt in bipolar disorder. Acta Psychiatrica Scandinavica, 120(1), 30-6. https://doi.org/10.1111/j.1600-0447.2008.01341.x
Sánchez-Gistau V, et al. Atypical Depression Is Associated With Suicide Attempt in Bipolar Disorder. Acta Psychiatr Scand. 2009;120(1):30-6. PubMed PMID: 19183125.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Atypical depression is associated with suicide attempt in bipolar disorder. AU - Sánchez-Gistau,V, AU - Colom,F, AU - Mané,A, AU - Romero,S, AU - Sugranyes,G, AU - Vieta,E, Y1 - 2009/01/12/ PY - 2009/2/3/entrez PY - 2009/2/3/pubmed PY - 2009/8/21/medline SP - 30 EP - 6 JF - Acta psychiatrica Scandinavica JO - Acta Psychiatr Scand VL - 120 IS - 1 N2 - OBJECTIVE: There is a dearth of research focusing on factors associated with suicide attempts. High rates of atypical depression have been reported in studies including unipolar and bipolar II patients. In this study, the association between suicide attempt and atypical depression, in addition to other major risk factors, was evaluated in 390 bipolar I and II out-patients. METHOD: Variables were defined according to DSM-IV criteria, and assessed with a Structured Interview for DSM-IV (axis I and II). History of suicide attempt was obtained through interviews with patients and relatives. Attempters and non-attempters were compared using univariate and multivariate analysis. RESULTS: Attempters showed significantly higher rates of atypical depression, family history of completed suicide, depression at index episode and cluster B personality disorder. CONCLUSION: Our results highlight the relevance of atypical depression in bipolar disorder. A more accurate identification of potential attempters may contribute to the development of effective preventive treatment strategies. SN - 1600-0447 UR - https://www.unboundmedicine.com/medline/citation/19183125/Atypical_depression_is_associated_with_suicide_attempt_in_bipolar_disorder_ L2 - https://doi.org/10.1111/j.1600-0447.2008.01341.x DB - PRIME DP - Unbound Medicine ER -