TY - JOUR T1 - Outcome of patients with acute myocardial infarction admitted in hospitals with or without catheterization laboratory: results from the HELIOS registry. AU - Pipilis,Athanasios, AU - Andrikopoulos,Georgios, AU - Lekakis,John, AU - Kalantzi,Kallirroi, AU - Kitsiou,Anastasia, AU - Toli,Konstantina, AU - Floros,Dimitrios, AU - Gaita,Dan, AU - Karalis,Ioannis, AU - Dragomanovits,Spyridon, AU - Kalogeropoulos,Petros, AU - Synetos,Andreas, AU - Koutsogiannis,Nikolaos, AU - Stougiannos,Pavlos, AU - Antonakoudis,Chariton, AU - Goudevenos,John, AU - ,, PY - 2009/2/4/entrez PY - 2009/2/4/pubmed PY - 2009/5/23/medline SP - 85 EP - 90 JF - European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology JO - Eur J Cardiovasc Prev Rehabil VL - 16 IS - 1 N2 - AIMS: To compare the treatment and outcomes of myocardial infarction patients in hospitals with and without catheterization laboratory. METHODS AND RESULTS: The Hellenic Infarction Observation Study was a countrywide registry of acute myocardial infarction, conducted during 2005-2006. The registry enrolled 1840 patients with myocardial infarction from 31 hospitals with a proportional representation of all types of hospitals and of all geographical areas. Out of these patients, 645 (35%) were admitted in 11 hospitals with and 1195 (65%) in 20 hospitals without catheterization laboratory. Patients admitted in hospitals with catheterization laboratory in comparison with patients admitted in hospitals without were younger (66+/-14 vs. 68+/-13, P<0.004) with less diabetes (27 vs. 33%, P<0.001), but without other baseline differences (female 27 vs. 25%, prior myocardial infarction 20 vs. 17%, Killip class>1 22 vs. 23%). Reperfusion rates for ST-segment elevation myocardial infarction were 67% (43% lytic, 24% primary percutaneous coronary interventions) versus 56% (55% lytic, 1% percutaneous coronary interventions; P<0.01). In-hospital outcomes in hospitals with versus in hospitals without laboratory were: mortality 6.5 versus 8.3% (NS), stroke 2.2 versus 1.1% (NS), major bleeding 1.1 versus 0.6% (NS), and heart failure 11 versus 16% (P<0.01). In multivariate regression analysis, being admitted in a hospital without catheterization laboratory was not an independent predictor of increased in-hospital mortality (odds ratio=1.18, 95% confidence interval: 0.72-1.93, P=0.505). CONCLUSION: Although the majority of acute myocardial infarction patients was admitted in hospitals without catheterization laboratory, these patients do not have a survival disadvantage, provided they are treated with lytic therapy, medical secondary prevention drugs, and eventual revascularization according to current guidelines. SN - 1741-8275 UR - https://www.unboundmedicine.com/medline/citation/19188809/Outcome_of_patients_with_acute_myocardial_infarction_admitted_in_hospitals_with_or_without_catheterization_laboratory:_results_from_the_HELIOS_registry_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&amp;PAGE=linkout&amp;SEARCH=19188809.ui DB - PRIME DP - Unbound Medicine ER -