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Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka.
Clin Infect Dis. 2009 Mar 01; 48 Suppl 2:S136-40.CI

Abstract

The South Asian Pneumococcal Surveillance network uses standard recruitment and laboratory procedures for surveillance of invasive pneumococcal disease in India, Nepal, and Sri Lanka. Children aged 2 months to 5 years who were admitted to the sentinel surveillance site, Lady Ridgeway Hospital for Children, in Colombo, Sri Lanka, and who presented with signs and symptoms of meningitis, pneumonia, or very severe disease were studied. Blood culture and CSF culture specimens were analyzed at the microbiology laboratory at Lady Ridgeway Hospital for Children. Specimens were processed by routine conventional methods. Antigen testing was performed on CSF specimens with use of commercially available latex agglutination test kits. From January 2005 to March 2007, we observed 23 isolates of Streptococcus pneumoniae, and the most common serotypes were 19F, 14, 23F, and 6B. Of the serotypes found, 60% are covered by the currently available 7-valent conjugate pneumococcal vaccine. More than 90% of the isolates were penicillin resistant, and the rate of resistance to third-generation cephalosporins was also high.

Authors+Show Affiliations

Epidemiogy Unit, Ministry of Health, Colombo, Sri Lanka. ranjithbatu@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19191609

Citation

Batuwanthudawe, R, et al. "Surveillance of Invasive Pneumococcal Disease in Colombo, Sri Lanka." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 48 Suppl 2, 2009, pp. S136-40.
Batuwanthudawe R, Karunarathne K, Dassanayake M, et al. Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka. Clin Infect Dis. 2009;48 Suppl 2:S136-40.
Batuwanthudawe, R., Karunarathne, K., Dassanayake, M., de Silva, S., Lalitha, M. K., Thomas, K., Steinhoff, M., & Abeysinghe, N. (2009). Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 48 Suppl 2, S136-40. https://doi.org/10.1086/596492
Batuwanthudawe R, et al. Surveillance of Invasive Pneumococcal Disease in Colombo, Sri Lanka. Clin Infect Dis. 2009 Mar 1;48 Suppl 2:S136-40. PubMed PMID: 19191609.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surveillance of invasive pneumococcal disease in Colombo, Sri Lanka. AU - Batuwanthudawe,R, AU - Karunarathne,K, AU - Dassanayake,M, AU - de Silva,S, AU - Lalitha,M K, AU - Thomas,K, AU - Steinhoff,M, AU - Abeysinghe,N, PY - 2009/2/5/entrez PY - 2009/2/24/pubmed PY - 2009/3/21/medline SP - S136 EP - 40 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 48 Suppl 2 N2 - The South Asian Pneumococcal Surveillance network uses standard recruitment and laboratory procedures for surveillance of invasive pneumococcal disease in India, Nepal, and Sri Lanka. Children aged 2 months to 5 years who were admitted to the sentinel surveillance site, Lady Ridgeway Hospital for Children, in Colombo, Sri Lanka, and who presented with signs and symptoms of meningitis, pneumonia, or very severe disease were studied. Blood culture and CSF culture specimens were analyzed at the microbiology laboratory at Lady Ridgeway Hospital for Children. Specimens were processed by routine conventional methods. Antigen testing was performed on CSF specimens with use of commercially available latex agglutination test kits. From January 2005 to March 2007, we observed 23 isolates of Streptococcus pneumoniae, and the most common serotypes were 19F, 14, 23F, and 6B. Of the serotypes found, 60% are covered by the currently available 7-valent conjugate pneumococcal vaccine. More than 90% of the isolates were penicillin resistant, and the rate of resistance to third-generation cephalosporins was also high. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/19191609/Surveillance_of_invasive_pneumococcal_disease_in_Colombo_Sri_Lanka_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/596492 DB - PRIME DP - Unbound Medicine ER -