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Performance of integrated FDG-PET/contrast-enhanced CT in the staging and restaging of colorectal cancer: comparison with PET and enhanced CT.
Eur J Radiol. 2010 Feb; 73(2):324-8.EJ

Abstract

OBJECTIVE

The purpose of this study was to assess the diagnostic value of PET/CT as a one step examination in patients with colorectal cancer. Therefore we proved whether diagnostic PET/CT adds information over PET or contrast-enhanced CT alone for staging or restaging of patients with colorectal cancer.

METHODS

Seventy-three patients (46 males and 27 females; age range: 50-81 years; mean age: 67 years) with known colorectal cancer underwent 18F-FDG-PET/CT for staging or restaging.

RESULTS

Of the 73 patients 26 patients underwent PET/CT for staging and 47 for restaging. 266 metastases could be detected in 60 patients. Contrast-enhanced PET/CT had a lesion-based sensitivity of 100%, contrast-enhanced CT of 91% and PET of 85%. PET/CT identified 2 lesions as false positive. PET/CT could also reach a patient-based sensitivity of 100%, which was superior to contrast-enhanced CT and PET.

CONCLUSION

Our study clearly demonstrated the added value of contrast-enhanced PET/CT in staging and restaging patients with colorectal cancer over CT and PET alone.

Authors+Show Affiliations

Department of Nuclear Medicine, St. Vincent's Hospital, Seilerstaette 4, 4010 Linz, Austria. albert.dirisamer@meduniwien.ac.atNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

19200683

Citation

Dirisamer, Albert, et al. "Performance of Integrated FDG-PET/contrast-enhanced CT in the Staging and Restaging of Colorectal Cancer: Comparison With PET and Enhanced CT." European Journal of Radiology, vol. 73, no. 2, 2010, pp. 324-8.
Dirisamer A, Halpern BS, Flöry D, et al. Performance of integrated FDG-PET/contrast-enhanced CT in the staging and restaging of colorectal cancer: comparison with PET and enhanced CT. Eur J Radiol. 2010;73(2):324-8.
Dirisamer, A., Halpern, B. S., Flöry, D., Wolf, F., Beheshti, M., Mayerhoefer, M. E., & Langsteger, W. (2010). Performance of integrated FDG-PET/contrast-enhanced CT in the staging and restaging of colorectal cancer: comparison with PET and enhanced CT. European Journal of Radiology, 73(2), 324-8. https://doi.org/10.1016/j.ejrad.2008.10.030
Dirisamer A, et al. Performance of Integrated FDG-PET/contrast-enhanced CT in the Staging and Restaging of Colorectal Cancer: Comparison With PET and Enhanced CT. Eur J Radiol. 2010;73(2):324-8. PubMed PMID: 19200683.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Performance of integrated FDG-PET/contrast-enhanced CT in the staging and restaging of colorectal cancer: comparison with PET and enhanced CT. AU - Dirisamer,Albert, AU - Halpern,Benjamin S, AU - Flöry,Daniel, AU - Wolf,Florian, AU - Beheshti,Mohsen, AU - Mayerhoefer,Marius E, AU - Langsteger,Werner, Y1 - 2009/02/05/ PY - 2008/10/24/received PY - 2008/10/27/revised PY - 2008/10/27/accepted PY - 2009/2/10/entrez PY - 2009/2/10/pubmed PY - 2010/5/18/medline SP - 324 EP - 8 JF - European journal of radiology JO - Eur J Radiol VL - 73 IS - 2 N2 - OBJECTIVE: The purpose of this study was to assess the diagnostic value of PET/CT as a one step examination in patients with colorectal cancer. Therefore we proved whether diagnostic PET/CT adds information over PET or contrast-enhanced CT alone for staging or restaging of patients with colorectal cancer. METHODS: Seventy-three patients (46 males and 27 females; age range: 50-81 years; mean age: 67 years) with known colorectal cancer underwent 18F-FDG-PET/CT for staging or restaging. RESULTS: Of the 73 patients 26 patients underwent PET/CT for staging and 47 for restaging. 266 metastases could be detected in 60 patients. Contrast-enhanced PET/CT had a lesion-based sensitivity of 100%, contrast-enhanced CT of 91% and PET of 85%. PET/CT identified 2 lesions as false positive. PET/CT could also reach a patient-based sensitivity of 100%, which was superior to contrast-enhanced CT and PET. CONCLUSION: Our study clearly demonstrated the added value of contrast-enhanced PET/CT in staging and restaging patients with colorectal cancer over CT and PET alone. SN - 1872-7727 UR - https://www.unboundmedicine.com/medline/citation/19200683/Performance_of_integrated_FDG_PET/contrast_enhanced_CT_in_the_staging_and_restaging_of_colorectal_cancer:_comparison_with_PET_and_enhanced_CT_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0720-048X(08)00594-9 DB - PRIME DP - Unbound Medicine ER -