Tags

Type your tag names separated by a space and hit enter

Erythrocyte membrane and plasma non-esterified n-3 and n-6 polyunsaturated fatty acids of pregnant and non-pregnant Brazilian adolescents.
Prostaglandins Leukot Essent Fatty Acids. 2009 Feb-Mar; 80(2-3):137-42.PL

Abstract

The aim of the present study was to evaluate the influence of pregnancy in adolescents on the fatty acid composition of the erythrocyte membrane, which was used as a proxy for status of n-3 and n-6 polyunsaturated fatty acids (PUFA), and also on the composition of plasma non-esterified fatty acids (NEFA) mobilized from the adipose tissue. Two matched groups of healthy adolescents (14-19 years) from Rio de Janeiro, Brazil, were compared: pregnant (n=26; 32.7+/-3.9 weeks of gestation, mean+/-SD) and non-pregnant (n=20). Blood samples were collected after an overnight fast. Mean dietary intakes of total fat and n-3 and n-6 PUFA (energy %) were not different between pregnant and non-pregnant adolescents, and the consumption of food sources of docosahexaenoic acid (DHA) was low. Fasting total NEFA and NEFA 18:2n-6, 18:3n-6 and 20:4n-6 (g/100g fatty acids) were higher in pregnant than in non-pregnant adolescents. Although erythrocyte 20:4n-6 was lower in pregnant adolescents, there were no differences in DHA (g/100g fatty acids), in DHA status indices (22:5n-6/22:4n-6 and 22:6n-3/22:5n-6 ratios) and in the index of n-3+n-6 PUFA status ([Sigman-3+Sigman-6]/[Sigman-7+Sigman-9]) in erythrocytes as compared with those of non-pregnant adolescents. In conclusion, pregnancy did not have an adverse effect on erythrocyte DHA content or on DHA and n-3+n-6 PUFA status indices in the adolescents studied.

Authors+Show Affiliations

Laboratório de Bioquímica Nutricional e de Alimentos, Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Cidade Universitária, CT bloco A, lab. 528, 21941-909 Rio de Janeiro, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19201181

Citation

Meneses, Flavia, et al. "Erythrocyte Membrane and Plasma Non-esterified N-3 and N-6 Polyunsaturated Fatty Acids of Pregnant and Non-pregnant Brazilian Adolescents." Prostaglandins, Leukotrienes, and Essential Fatty Acids, vol. 80, no. 2-3, 2009, pp. 137-42.
Meneses F, Ney JG, Torres AG, et al. Erythrocyte membrane and plasma non-esterified n-3 and n-6 polyunsaturated fatty acids of pregnant and non-pregnant Brazilian adolescents. Prostaglandins Leukot Essent Fatty Acids. 2009;80(2-3):137-42.
Meneses, F., Ney, J. G., Torres, A. G., & Trugo, N. M. (2009). Erythrocyte membrane and plasma non-esterified n-3 and n-6 polyunsaturated fatty acids of pregnant and non-pregnant Brazilian adolescents. Prostaglandins, Leukotrienes, and Essential Fatty Acids, 80(2-3), 137-42. https://doi.org/10.1016/j.plefa.2008.12.005
Meneses F, et al. Erythrocyte Membrane and Plasma Non-esterified N-3 and N-6 Polyunsaturated Fatty Acids of Pregnant and Non-pregnant Brazilian Adolescents. Prostaglandins Leukot Essent Fatty Acids. 2009 Feb-Mar;80(2-3):137-42. PubMed PMID: 19201181.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Erythrocyte membrane and plasma non-esterified n-3 and n-6 polyunsaturated fatty acids of pregnant and non-pregnant Brazilian adolescents. AU - Meneses,Flavia, AU - Ney,Jacqueline G, AU - Torres,Alexandre G, AU - Trugo,Nadia M F, Y1 - 2009/02/06/ PY - 2008/03/26/received PY - 2008/12/03/revised PY - 2008/12/21/accepted PY - 2009/2/10/entrez PY - 2009/2/10/pubmed PY - 2009/7/1/medline SP - 137 EP - 42 JF - Prostaglandins, leukotrienes, and essential fatty acids JO - Prostaglandins Leukot. Essent. Fatty Acids VL - 80 IS - 2-3 N2 - The aim of the present study was to evaluate the influence of pregnancy in adolescents on the fatty acid composition of the erythrocyte membrane, which was used as a proxy for status of n-3 and n-6 polyunsaturated fatty acids (PUFA), and also on the composition of plasma non-esterified fatty acids (NEFA) mobilized from the adipose tissue. Two matched groups of healthy adolescents (14-19 years) from Rio de Janeiro, Brazil, were compared: pregnant (n=26; 32.7+/-3.9 weeks of gestation, mean+/-SD) and non-pregnant (n=20). Blood samples were collected after an overnight fast. Mean dietary intakes of total fat and n-3 and n-6 PUFA (energy %) were not different between pregnant and non-pregnant adolescents, and the consumption of food sources of docosahexaenoic acid (DHA) was low. Fasting total NEFA and NEFA 18:2n-6, 18:3n-6 and 20:4n-6 (g/100g fatty acids) were higher in pregnant than in non-pregnant adolescents. Although erythrocyte 20:4n-6 was lower in pregnant adolescents, there were no differences in DHA (g/100g fatty acids), in DHA status indices (22:5n-6/22:4n-6 and 22:6n-3/22:5n-6 ratios) and in the index of n-3+n-6 PUFA status ([Sigman-3+Sigman-6]/[Sigman-7+Sigman-9]) in erythrocytes as compared with those of non-pregnant adolescents. In conclusion, pregnancy did not have an adverse effect on erythrocyte DHA content or on DHA and n-3+n-6 PUFA status indices in the adolescents studied. SN - 0952-3278 UR - https://www.unboundmedicine.com/medline/citation/19201181/Erythrocyte_membrane_and_plasma_non_esterified_n_3_and_n_6_polyunsaturated_fatty_acids_of_pregnant_and_non_pregnant_Brazilian_adolescents_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0952-3278(08)00193-2 DB - PRIME DP - Unbound Medicine ER -