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Can rhizoma chuanxiong replace radix Angelica sinensis in the traditional Chinese herbal decoction danggui buxue tang?
Planta Med. 2009 May; 75(6):602-6.PM

Abstract

Herein, we test the hypothesis that a member of a formulated Chinese herbal decoction cannot be replaced by another herb. Danggui Buxue Tang (DBT) is being used as an example for illustration: this is a traditional decoction containing Radix Astragali (RA) and Radix Angelicae Sinensis (RAS) in a weight ratio of 5 to 1. Rhizoma Chuanxiong (RC) and RAS are two chemically very similar herbs but with a distinct function. Following the preparation method of DBT, a herbal decoction, namely Chuanxiong Buxue Tang (CBT), was created, which contained RA and RC in a weight ratio of 5 to 1. The two decoctions, DBT and CBT, were compared in parallel regarding their chemical and biological properties. In all the tested parameters, DBT showed superior properties, both chemically and biologically, to that of CBT. The current results reveal the uniqueness of Chinese herbal decoctions that require a well-defined formulation, which is indispensable for its specific composition.

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Authors+Show Affiliations

Li WZ
Department of Biology and Center for Chinese Medicine, The Hong Kong University of Science and Technology, Hong Kong, PR China.
Li J
No affiliation info available
Bi CW
No affiliation info available
Cheung AW
No affiliation info available
Huang W
No affiliation info available
Duan R
No affiliation info available
Choi RC
No affiliation info available
Chen IS
No affiliation info available
Zhao KJ
No affiliation info available
Dong TT
No affiliation info available
Duan JA
No affiliation info available
Tsim KW
No affiliation info available

MeSH

Angelica sinensisAstragalus propinquusCell LineCell Line, TumorDrug CompoundingDrugs, Chinese HerbalExtracellular Signal-Regulated MAP KinasesFemaleHumansImmunologic FactorsLigusticumOsteoblastsPhosphorylationPhytoestrogensPlant RootsRhizomeT-Lymphocytes

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19204892

Citation

Li, Winnie Z M., et al. "Can Rhizoma Chuanxiong Replace Radix Angelica Sinensis in the Traditional Chinese Herbal Decoction Danggui Buxue Tang?" Planta Medica, vol. 75, no. 6, 2009, pp. 602-6.
Li WZ, Li J, Bi CW, et al. Can rhizoma chuanxiong replace radix Angelica sinensis in the traditional Chinese herbal decoction danggui buxue tang? Planta Med. 2009;75(6):602-6.
Li, W. Z., Li, J., Bi, C. W., Cheung, A. W., Huang, W., Duan, R., Choi, R. C., Chen, I. S., Zhao, K. J., Dong, T. T., Duan, J. A., & Tsim, K. W. (2009). Can rhizoma chuanxiong replace radix Angelica sinensis in the traditional Chinese herbal decoction danggui buxue tang? Planta Medica, 75(6), 602-6. https://doi.org/10.1055/s-0029-1185361
Li WZ, et al. Can Rhizoma Chuanxiong Replace Radix Angelica Sinensis in the Traditional Chinese Herbal Decoction Danggui Buxue Tang. Planta Med. 2009;75(6):602-6. PubMed PMID: 19204892.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Can rhizoma chuanxiong replace radix Angelica sinensis in the traditional Chinese herbal decoction danggui buxue tang? AU - Li,Winnie Z M, AU - Li,Jun, AU - Bi,Cathy W C, AU - Cheung,Anna W H, AU - Huang,Wen, AU - Duan,Ran, AU - Choi,Roy C Y, AU - Chen,Ivy S Y, AU - Zhao,Kui J, AU - Dong,Tina T X, AU - Duan,Jin A, AU - Tsim,Karl W K, Y1 - 2009/02/09/ PY - 2009/2/11/entrez PY - 2009/2/11/pubmed PY - 2009/11/7/medline SP - 602 EP - 6 JF - Planta medica JO - Planta Med VL - 75 IS - 6 N2 - Herein, we test the hypothesis that a member of a formulated Chinese herbal decoction cannot be replaced by another herb. Danggui Buxue Tang (DBT) is being used as an example for illustration: this is a traditional decoction containing Radix Astragali (RA) and Radix Angelicae Sinensis (RAS) in a weight ratio of 5 to 1. Rhizoma Chuanxiong (RC) and RAS are two chemically very similar herbs but with a distinct function. Following the preparation method of DBT, a herbal decoction, namely Chuanxiong Buxue Tang (CBT), was created, which contained RA and RC in a weight ratio of 5 to 1. The two decoctions, DBT and CBT, were compared in parallel regarding their chemical and biological properties. In all the tested parameters, DBT showed superior properties, both chemically and biologically, to that of CBT. The current results reveal the uniqueness of Chinese herbal decoctions that require a well-defined formulation, which is indispensable for its specific composition. SN - 1439-0221 UR - https://www.unboundmedicine.com/medline/citation/19204892/Can_rhizoma_chuanxiong_replace_radix_Angelica_sinensis_in_the_traditional_Chinese_herbal_decoction_danggui_buxue_tang L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0029-1185361 DB - PRIME DP - Unbound Medicine ER -
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