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Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program.
Acta Psychiatr Scand. 2009 Jun; 119(6):494-500.AP

Abstract

OBJECTIVE

Psychotic disorders often start in adolescence. We aim to investigate premorbid and baseline differences characterizing patients with an onset of psychosis in adolescence versus adulthood.

METHOD

We compare first-episode, DSM-IV non-affective psychosis with onset before (n = 43) and after (n = 189) 18 years on duration of untreated psychosis (DUP), level of symptoms, suicidal behaviour, and other baseline clinical and demographic characteristics.

RESULTS

Adolescent onset patients had poorer premorbid functioning, a longer DUP, higher suicidality, and more depressive symptoms. They also had better cognition, fewer psychotic symptoms, and were more likely to be treated on an out-patient basis.

CONCLUSION

Adolescents with first-episode psychosis may have a slower and more silent, i.e. insidious onset, and are at risk of experiencing longer treatment delays than adults. They fit the description of what used to be labeled process (versus reactive) schizophrenia.

Authors+Show Affiliations

Psychiatric Division, Regional Centre for Clinical Research in Psychosis, Stavanger University Hospital, Stavanger, Norway. ijo@sus.noNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19207132

Citation

Joa, I, et al. "Baseline Profiles of Adolescent Vs. Adult-onset First-episode Psychosis in an Early Detection Program." Acta Psychiatrica Scandinavica, vol. 119, no. 6, 2009, pp. 494-500.
Joa I, Johannessen JO, Langeveld J, et al. Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program. Acta Psychiatr Scand. 2009;119(6):494-500.
Joa, I., Johannessen, J. O., Langeveld, J., Friis, S., Melle, I., Opjordsmoen, S., Simonsen, E., Vaglum, P., McGlashan, T., & Larsen, T. K. (2009). Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program. Acta Psychiatrica Scandinavica, 119(6), 494-500. https://doi.org/10.1111/j.1600-0447.2008.01338.x
Joa I, et al. Baseline Profiles of Adolescent Vs. Adult-onset First-episode Psychosis in an Early Detection Program. Acta Psychiatr Scand. 2009;119(6):494-500. PubMed PMID: 19207132.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program. AU - Joa,I, AU - Johannessen,J O, AU - Langeveld,J, AU - Friis,S, AU - Melle,I, AU - Opjordsmoen,S, AU - Simonsen,E, AU - Vaglum,P, AU - McGlashan,T, AU - Larsen,T K, Y1 - 2009/02/05/ PY - 2009/2/12/entrez PY - 2009/2/12/pubmed PY - 2009/8/7/medline SP - 494 EP - 500 JF - Acta psychiatrica Scandinavica JO - Acta Psychiatr Scand VL - 119 IS - 6 N2 - OBJECTIVE: Psychotic disorders often start in adolescence. We aim to investigate premorbid and baseline differences characterizing patients with an onset of psychosis in adolescence versus adulthood. METHOD: We compare first-episode, DSM-IV non-affective psychosis with onset before (n = 43) and after (n = 189) 18 years on duration of untreated psychosis (DUP), level of symptoms, suicidal behaviour, and other baseline clinical and demographic characteristics. RESULTS: Adolescent onset patients had poorer premorbid functioning, a longer DUP, higher suicidality, and more depressive symptoms. They also had better cognition, fewer psychotic symptoms, and were more likely to be treated on an out-patient basis. CONCLUSION: Adolescents with first-episode psychosis may have a slower and more silent, i.e. insidious onset, and are at risk of experiencing longer treatment delays than adults. They fit the description of what used to be labeled process (versus reactive) schizophrenia. SN - 1600-0447 UR - https://www.unboundmedicine.com/medline/citation/19207132/Baseline_profiles_of_adolescent_vs__adult_onset_first_episode_psychosis_in_an_early_detection_program_ L2 - https://doi.org/10.1111/j.1600-0447.2008.01338.x DB - PRIME DP - Unbound Medicine ER -