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Efficacy of five chemicals on Fasciola gigantica encysted metacercariae infectivity.
J Egypt Soc Parasitol. 2008 Dec; 38(3):919-28.JE

Abstract

The efficacy of treating encysted metacercariae (EMC) of Fasciola gigantica with different concentrations (conc.) of acetic acid, citric acid, cetrimide, potassium permanganate and sodium hydroxide, for 15 & 30 minutes was evaluated. The efficacy of these chemicals on the vitality and infectivity of the EMC was evaluated by the development of fascioliasis infection, and the histopathological changes in the livers of experimentally infected Albino rabbits. The results showed that 1% sodium hydroxide had a lethal effect on EMC, 10% to 40% potassium permanganate destroyed the infectivity power of EMC, and acetic acid gave an adverse effect on the EMC in conc. more than 2.5%. But, neither citric acid nor cetrimide affected the vitality or infectivity of EMC and all rabbits acquired fascioliasis.

Authors+Show Affiliations

Hassan AA
Department of Parasitology, Faculty of Veterinary Medicine, University of Cairo University, Egypt.
Shoukary NM
No affiliation info available
El-Motayam M
No affiliation info available
Morsy AT
No affiliation info available

MeSH

Acetic AcidAnimalsAnthelminticsAnti-Infective Agents, LocalCetrimoniumCetrimonium CompoundsCitric AcidDose-Response Relationship, DrugFasciolaFascioliasisFemaleHumansMaleParasite Egg CountPotassium PermanganateRabbitsRandom AllocationSnailsSodium HydroxideTime Factors

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19209774

Citation

Hassan, Ali Awad A., et al. "Efficacy of Five Chemicals On Fasciola Gigantica Encysted Metacercariae Infectivity." Journal of the Egyptian Society of Parasitology, vol. 38, no. 3, 2008, pp. 919-28.
Hassan AA, Shoukary NM, El-Motayam M, et al. Efficacy of five chemicals on Fasciola gigantica encysted metacercariae infectivity. J Egypt Soc Parasitol. 2008;38(3):919-28.
Hassan, A. A., Shoukary, N. M., El-Motayam, M., & Morsy, A. T. (2008). Efficacy of five chemicals on Fasciola gigantica encysted metacercariae infectivity. Journal of the Egyptian Society of Parasitology, 38(3), 919-28.
Hassan AA, et al. Efficacy of Five Chemicals On Fasciola Gigantica Encysted Metacercariae Infectivity. J Egypt Soc Parasitol. 2008;38(3):919-28. PubMed PMID: 19209774.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of five chemicals on Fasciola gigantica encysted metacercariae infectivity. AU - Hassan,Ali Awad A, AU - Shoukary,Nahla M, AU - El-Motayam,Mona, AU - Morsy,Ayman T A, PY - 2009/2/13/entrez PY - 2009/2/13/pubmed PY - 2009/3/17/medline SP - 919 EP - 28 JF - Journal of the Egyptian Society of Parasitology JO - J Egypt Soc Parasitol VL - 38 IS - 3 N2 - The efficacy of treating encysted metacercariae (EMC) of Fasciola gigantica with different concentrations (conc.) of acetic acid, citric acid, cetrimide, potassium permanganate and sodium hydroxide, for 15 & 30 minutes was evaluated. The efficacy of these chemicals on the vitality and infectivity of the EMC was evaluated by the development of fascioliasis infection, and the histopathological changes in the livers of experimentally infected Albino rabbits. The results showed that 1% sodium hydroxide had a lethal effect on EMC, 10% to 40% potassium permanganate destroyed the infectivity power of EMC, and acetic acid gave an adverse effect on the EMC in conc. more than 2.5%. But, neither citric acid nor cetrimide affected the vitality or infectivity of EMC and all rabbits acquired fascioliasis. SN - 1110-0583 UR - https://www.unboundmedicine.com/medline/citation/19209774/Efficacy_of_five_chemicals_on_Fasciola_gigantica_encysted_metacercariae_infectivity_ DB - PRIME DP - Unbound Medicine ER -