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Wernicke's encephalopathy and Korsakoff's psychosis: to fortify or not to fortify?
Neurotoxicol Teratol. 1991 Jul-Aug; 13(4):353-5.NT

Abstract

The conventional wisdom suggests that Korsakoff's psychosis, an amnesic disorder associated with prolonged alcohol consumption, is the chronic outcome of a thiamin deficiency first exhibited as Wernicke's encephalopathy. The present paper describes the debate in Australia over whether flour and alcoholic beverages should be fortified with thiamin, in an attempt to prevent Wernicke's encephalopathy and thus Korsakoff's psychosis. We conclude that the scientific evidence linking Wernicke's encephalopathy and Korsakoff's psychosis is tenuous. Certainly, it is not sufficient to support what would amount to mass medication.

Authors+Show Affiliations

Bond NW
School of Behavioural Sciences, Macquarie University, NSW, Australia.
Homewood J
No affiliation info available

MeSH

Alcohol Amnestic DisorderAlcoholic BeveragesAlcoholismAustraliaFlourFood, FortifiedHumansThiamineThiamine DeficiencyWernicke Encephalopathy

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

1921914

Citation

Bond, N W., and J Homewood. "Wernicke's Encephalopathy and Korsakoff's Psychosis: to Fortify or Not to Fortify?" Neurotoxicology and Teratology, vol. 13, no. 4, 1991, pp. 353-5.
Bond NW, Homewood J. Wernicke's encephalopathy and Korsakoff's psychosis: to fortify or not to fortify? Neurotoxicol Teratol. 1991;13(4):353-5.
Bond, N. W., & Homewood, J. (1991). Wernicke's encephalopathy and Korsakoff's psychosis: to fortify or not to fortify? Neurotoxicology and Teratology, 13(4), 353-5.
Bond NW, Homewood J. Wernicke's Encephalopathy and Korsakoff's Psychosis: to Fortify or Not to Fortify. Neurotoxicol Teratol. 1991 Jul-Aug;13(4):353-5. PubMed PMID: 1921914.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Wernicke's encephalopathy and Korsakoff's psychosis: to fortify or not to fortify? AU - Bond,N W, AU - Homewood,J, PY - 1991/7/1/pubmed PY - 1991/7/1/medline PY - 1991/7/1/entrez SP - 353 EP - 5 JF - Neurotoxicology and teratology JO - Neurotoxicol Teratol VL - 13 IS - 4 N2 - The conventional wisdom suggests that Korsakoff's psychosis, an amnesic disorder associated with prolonged alcohol consumption, is the chronic outcome of a thiamin deficiency first exhibited as Wernicke's encephalopathy. The present paper describes the debate in Australia over whether flour and alcoholic beverages should be fortified with thiamin, in an attempt to prevent Wernicke's encephalopathy and thus Korsakoff's psychosis. We conclude that the scientific evidence linking Wernicke's encephalopathy and Korsakoff's psychosis is tenuous. Certainly, it is not sufficient to support what would amount to mass medication. SN - 0892-0362 UR - https://www.unboundmedicine.com/medline/citation/1921914/Wernicke's_encephalopathy_and_Korsakoff's_psychosis:_to_fortify_or_not_to_fortify DB - PRIME DP - Unbound Medicine ER -