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Microbial transformation of dehydroandrographolide by Cunninghamella elegans.
J Asian Nat Prod Res. 2009; 11(2):187-91.JA

Abstract

The biotransformation of dehydroandrographolide (1) by Cunninghamella elegans was performed and four transformed products were obtained. Based on their extensive spectral data, the structures of these metabolites were identified as 3-oxo-dehydroandrographolide (2), 3-oxo-2beta-hydroxy-dehydroandrographolide (3), 3-oxo-8beta,17alpha-epoxydehydroandrographolide (4), 3,19-dihydroxy-7,11,13-ent-labdatrien-15,16-olide (5), respectively. Among them, products 3-5 are new compounds.

Authors+Show Affiliations

Key Laboratory of Bioprocess of Beijing, Beijing University of Chemical Technology, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19219734

Citation

Xin, Xiu-Lan, et al. "Microbial Transformation of Dehydroandrographolide By Cunninghamella Elegans." Journal of Asian Natural Products Research, vol. 11, no. 2, 2009, pp. 187-91.
Xin XL, Ma XC, Zhang BJ, et al. Microbial transformation of dehydroandrographolide by Cunninghamella elegans. J Asian Nat Prod Res. 2009;11(2):187-91.
Xin, X. L., Ma, X. C., Zhang, B. J., Su, D. H., Wu, Z. M., Wang, X. J., Li, X. Y., & Yuan, Q. P. (2009). Microbial transformation of dehydroandrographolide by Cunninghamella elegans. Journal of Asian Natural Products Research, 11(2), 187-91. https://doi.org/10.1080/10286020802619280
Xin XL, et al. Microbial Transformation of Dehydroandrographolide By Cunninghamella Elegans. J Asian Nat Prod Res. 2009;11(2):187-91. PubMed PMID: 19219734.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Microbial transformation of dehydroandrographolide by Cunninghamella elegans. AU - Xin,Xiu-Lan, AU - Ma,Xiao-Chi, AU - Zhang,Bao-Jing, AU - Su,Dong-Hai, AU - Wu,Zhi-Ming, AU - Wang,Xiao-Jie, AU - Li,Xiao-Yan, AU - Yuan,Qi-Peng, PY - 2009/2/17/entrez PY - 2009/2/17/pubmed PY - 2009/4/17/medline SP - 187 EP - 91 JF - Journal of Asian natural products research JO - J Asian Nat Prod Res VL - 11 IS - 2 N2 - The biotransformation of dehydroandrographolide (1) by Cunninghamella elegans was performed and four transformed products were obtained. Based on their extensive spectral data, the structures of these metabolites were identified as 3-oxo-dehydroandrographolide (2), 3-oxo-2beta-hydroxy-dehydroandrographolide (3), 3-oxo-8beta,17alpha-epoxydehydroandrographolide (4), 3,19-dihydroxy-7,11,13-ent-labdatrien-15,16-olide (5), respectively. Among them, products 3-5 are new compounds. SN - 1477-2213 UR - https://www.unboundmedicine.com/medline/citation/19219734/Microbial_transformation_of_dehydroandrographolide_by_Cunninghamella_elegans_ L2 - http://www.tandfonline.com/doi/full/10.1080/10286020802619280 DB - PRIME DP - Unbound Medicine ER -