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Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study.
Eur Radiol. 2009 Jul; 19(7):1653-60.ER

Abstract

The aim of this study was to determine the predictive value of 64-slice computed tomography coronary angiography (CTCA) for major cardiac events in patients with suspected coronary artery disease (CAD). A total of 187 consecutive patients (119 men, age 62.5 +/- 10.5 years) without known heart disease underwent single-source 64-slice CTCA (Somatom Sensation 64, Siemens) for clinical suspicion of CAD. Patients underwent follow-up for the occurrence of cardiac death, nonfatal myocardial infarction, unstable angina and cardiac revascularization. In total, 2,822 coronary segments were assessed. Forty-two segments (1.5%) were not assessable because of insufficient image quality. Overall, CTCA revealed absence of CAD in 65 (34.7%) patients, nonobstructive CAD (coronary plaque < or =50%) in 87 (46.5%) patients and obstructive CAD (>50%) in 35 (18.8%) patients. A total of 20 major cardiac events (3 myocardial infarctions, 16 cardiac revascularizations, 1 unstable angina) occurred during a mean follow-up of 24 months. One noncardiac death occurred. Seventeen events occurred in the group of patients with obstructive CAD and three events occurred in the group of nonobstructive CAD. The event rate was 0% among patients with normal coronary arteries at CTCA. CTCA has a 100% negative predictive value for major cardiac events at 24-month follow-up in patients with normal coronary arteries.

Authors+Show Affiliations

Department of Radiology and Cardiology, Azienda Ospedaliero-Universitaria, Parma, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

19224218

Citation

Aldrovandi, Annachiara, et al. "Prognostic Value of Computed Tomography Coronary Angiography in Patients With Suspected Coronary Artery Disease: a 24-month Follow-up Study." European Radiology, vol. 19, no. 7, 2009, pp. 1653-60.
Aldrovandi A, Maffei E, Palumbo A, et al. Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study. Eur Radiol. 2009;19(7):1653-60.
Aldrovandi, A., Maffei, E., Palumbo, A., Seitun, S., Martini, C., Brambilla, V., Zuccarelli, A., Tarantini, G., Weustink, A. C., Mollet, N. R., Ruffini, L., Crisi, G., Ardissino, D., de Feyter, P. J., Krestin, G. P., & Cademartiri, F. (2009). Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study. European Radiology, 19(7), 1653-60. https://doi.org/10.1007/s00330-009-1344-3
Aldrovandi A, et al. Prognostic Value of Computed Tomography Coronary Angiography in Patients With Suspected Coronary Artery Disease: a 24-month Follow-up Study. Eur Radiol. 2009;19(7):1653-60. PubMed PMID: 19224218.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prognostic value of computed tomography coronary angiography in patients with suspected coronary artery disease: a 24-month follow-up study. AU - Aldrovandi,Annachiara, AU - Maffei,Erica, AU - Palumbo,Alessandro, AU - Seitun,Sara, AU - Martini,Chiara, AU - Brambilla,Valerio, AU - Zuccarelli,Alessandra, AU - Tarantini,Giuseppe, AU - Weustink,Annick C, AU - Mollet,Nico R, AU - Ruffini,Livia, AU - Crisi,Girolamo, AU - Ardissino,Diego, AU - de Feyter,Pim J, AU - Krestin,Gabriel P, AU - Cademartiri,Filippo, Y1 - 2009/02/18/ PY - 2008/08/11/received PY - 2009/01/08/accepted PY - 2008/12/31/revised PY - 2009/2/19/entrez PY - 2009/2/19/pubmed PY - 2009/8/20/medline SP - 1653 EP - 60 JF - European radiology JO - Eur Radiol VL - 19 IS - 7 N2 - The aim of this study was to determine the predictive value of 64-slice computed tomography coronary angiography (CTCA) for major cardiac events in patients with suspected coronary artery disease (CAD). A total of 187 consecutive patients (119 men, age 62.5 +/- 10.5 years) without known heart disease underwent single-source 64-slice CTCA (Somatom Sensation 64, Siemens) for clinical suspicion of CAD. Patients underwent follow-up for the occurrence of cardiac death, nonfatal myocardial infarction, unstable angina and cardiac revascularization. In total, 2,822 coronary segments were assessed. Forty-two segments (1.5%) were not assessable because of insufficient image quality. Overall, CTCA revealed absence of CAD in 65 (34.7%) patients, nonobstructive CAD (coronary plaque < or =50%) in 87 (46.5%) patients and obstructive CAD (>50%) in 35 (18.8%) patients. A total of 20 major cardiac events (3 myocardial infarctions, 16 cardiac revascularizations, 1 unstable angina) occurred during a mean follow-up of 24 months. One noncardiac death occurred. Seventeen events occurred in the group of patients with obstructive CAD and three events occurred in the group of nonobstructive CAD. The event rate was 0% among patients with normal coronary arteries at CTCA. CTCA has a 100% negative predictive value for major cardiac events at 24-month follow-up in patients with normal coronary arteries. SN - 1432-1084 UR - https://www.unboundmedicine.com/medline/citation/19224218/Prognostic_value_of_computed_tomography_coronary_angiography_in_patients_with_suspected_coronary_artery_disease:_a_24_month_follow_up_study_ L2 - https://dx.doi.org/10.1007/s00330-009-1344-3 DB - PRIME DP - Unbound Medicine ER -