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Extramedullary plasmacytoma of the larynx in an adolescent: a case report and review of the literature.
Ear Nose Throat J. 2009 Feb; 88(2):E1-7.EN

Abstract

Extramedullary plasmacytoma is uncommon, accounting for only 3% of all plasma cell neoplasms. Most lesions occur in the head and neck, primarily in the upper aerodigestive tract; only a minority occur in the larynx. Most cases of extramedullary plasmacytoma are seen in older men; presentation in an adolescent is rare. We report the case of a 13-year-old girl who presented with a 2- to 3-month history of progressive dysphonia. Physical examination identified two lesions--a nasopharyngeal mass and a laryngeal mass. Biopsy indicated that the masses were extramedullary plasmacytomas with amyloid deposition. The patient was treated with radiation therapy, and the tumors were eradicated. We also review the literature with respect to the epidemiology and presentation of extramedullary plasmacytoma of the head and neck, specifically those that affect the larynx.

Authors+Show Affiliations

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Connecticut School of Medicine, 263 Farmington Ave., Farmington, CT 06030, USA. kdruther@gmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

19224468

Citation

Rutherford, Kimberley, et al. "Extramedullary Plasmacytoma of the Larynx in an Adolescent: a Case Report and Review of the Literature." Ear, Nose, & Throat Journal, vol. 88, no. 2, 2009, pp. E1-7.
Rutherford K, Parsons S, Cordes S. Extramedullary plasmacytoma of the larynx in an adolescent: a case report and review of the literature. Ear Nose Throat J. 2009;88(2):E1-7.
Rutherford, K., Parsons, S., & Cordes, S. (2009). Extramedullary plasmacytoma of the larynx in an adolescent: a case report and review of the literature. Ear, Nose, & Throat Journal, 88(2), E1-7.
Rutherford K, Parsons S, Cordes S. Extramedullary Plasmacytoma of the Larynx in an Adolescent: a Case Report and Review of the Literature. Ear Nose Throat J. 2009;88(2):E1-7. PubMed PMID: 19224468.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extramedullary plasmacytoma of the larynx in an adolescent: a case report and review of the literature. AU - Rutherford,Kimberley, AU - Parsons,Stephen, AU - Cordes,Susan, PY - 2009/2/19/entrez PY - 2009/2/19/pubmed PY - 2010/9/2/medline SP - E1 EP - 7 JF - Ear, nose, & throat journal JO - Ear Nose Throat J VL - 88 IS - 2 N2 - Extramedullary plasmacytoma is uncommon, accounting for only 3% of all plasma cell neoplasms. Most lesions occur in the head and neck, primarily in the upper aerodigestive tract; only a minority occur in the larynx. Most cases of extramedullary plasmacytoma are seen in older men; presentation in an adolescent is rare. We report the case of a 13-year-old girl who presented with a 2- to 3-month history of progressive dysphonia. Physical examination identified two lesions--a nasopharyngeal mass and a laryngeal mass. Biopsy indicated that the masses were extramedullary plasmacytomas with amyloid deposition. The patient was treated with radiation therapy, and the tumors were eradicated. We also review the literature with respect to the epidemiology and presentation of extramedullary plasmacytoma of the head and neck, specifically those that affect the larynx. SN - 1942-7522 UR - https://www.unboundmedicine.com/medline/citation/19224468/Extramedullary_plasmacytoma_of_the_larynx_in_an_adolescent:_a_case_report_and_review_of_the_literature_ DB - PRIME DP - Unbound Medicine ER -