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Correlation of intraocular pressure measured with goldmann and dynamic contour tonometry in normal and glaucomatous eyes.
J Glaucoma 2009; 18(2):119-23JG

Abstract

PURPOSE

To compare intraocular pressure (IOP) values measured by both Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) in both normal and glaucomatous eyes, and to determine the relationship between these parameters and central corneal thickness (CCT).

PATIENTS AND METHODS

Forty-seven subjects with primary open-angle glaucoma and 38 normal subjects attended a 12-hour session during which IOP was assessed at 7 time points, every 2 hours, by both GAT and DCT. CCT was also assessed at the same visit. Mean IOP was calculated for each eye of each subject by each method from the 7 diurnal IOP measurements obtained.

RESULTS

Mean IOP was higher when measured by DCT than by GAT in both normal (by 1.1 mm Hg, P<0.0001) and glaucomatous (by 1.6 mm Hg, P<0.0001) eyes. IOP measurements by GAT and DCT were moderately correlated in both normal (r(2)=0.354, P<0.0001) and glaucomatous (r(2)=0.552, P<0.0001) eyes. In normal eyes, there was a weak positive correlation between GAT IOP and CCT (r(2)=0.088, slope=0.022 mm Hg/microm, P=0.009) and no correlation between DCT IOP and CCT (r(2)=0.007, slope=0.005 mm Hg/microm, P=0.468). In glaucomatous eyes, there was no correlation between GAT IOP and CCT (r(2)=0.006, slope=0.007 mm Hg/microm, P=0.473) and a weak inverse correlation between DCT IOP and CCT (r(2)=0.075, slope=-0.021 mm Hg/microm, P=0.008).

CONCLUSIONS

Both GAT and DCT are affected by CCT, albeit in different ways. Normal and glaucomatous eyes exhibit different relationships between CCT and IOP measured by either GAT or DCT. The relationships between CCT and transcorneal IOP measurements are complex and incompletely characterized, which limits the clinical interpretation of GAT and DCT measurements of IOP in both normal and glaucomatous eyes.

Authors+Show Affiliations

Department of Ophthalmology, West Virginia University, Morgantown, WV, USA. realinia@wvuh.comNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

19225347

Citation

Realini, Tony, et al. "Correlation of Intraocular Pressure Measured With Goldmann and Dynamic Contour Tonometry in Normal and Glaucomatous Eyes." Journal of Glaucoma, vol. 18, no. 2, 2009, pp. 119-23.
Realini T, Weinreb RN, Hobbs G. Correlation of intraocular pressure measured with goldmann and dynamic contour tonometry in normal and glaucomatous eyes. J Glaucoma. 2009;18(2):119-23.
Realini, T., Weinreb, R. N., & Hobbs, G. (2009). Correlation of intraocular pressure measured with goldmann and dynamic contour tonometry in normal and glaucomatous eyes. Journal of Glaucoma, 18(2), pp. 119-23. doi:10.1097/IJG.0b013e31817d23c7.
Realini T, Weinreb RN, Hobbs G. Correlation of Intraocular Pressure Measured With Goldmann and Dynamic Contour Tonometry in Normal and Glaucomatous Eyes. J Glaucoma. 2009;18(2):119-23. PubMed PMID: 19225347.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Correlation of intraocular pressure measured with goldmann and dynamic contour tonometry in normal and glaucomatous eyes. AU - Realini,Tony, AU - Weinreb,Robert N, AU - Hobbs,Gerald, PY - 2009/2/20/entrez PY - 2009/2/20/pubmed PY - 2009/5/27/medline SP - 119 EP - 23 JF - Journal of glaucoma JO - J. Glaucoma VL - 18 IS - 2 N2 - PURPOSE: To compare intraocular pressure (IOP) values measured by both Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) in both normal and glaucomatous eyes, and to determine the relationship between these parameters and central corneal thickness (CCT). PATIENTS AND METHODS: Forty-seven subjects with primary open-angle glaucoma and 38 normal subjects attended a 12-hour session during which IOP was assessed at 7 time points, every 2 hours, by both GAT and DCT. CCT was also assessed at the same visit. Mean IOP was calculated for each eye of each subject by each method from the 7 diurnal IOP measurements obtained. RESULTS: Mean IOP was higher when measured by DCT than by GAT in both normal (by 1.1 mm Hg, P<0.0001) and glaucomatous (by 1.6 mm Hg, P<0.0001) eyes. IOP measurements by GAT and DCT were moderately correlated in both normal (r(2)=0.354, P<0.0001) and glaucomatous (r(2)=0.552, P<0.0001) eyes. In normal eyes, there was a weak positive correlation between GAT IOP and CCT (r(2)=0.088, slope=0.022 mm Hg/microm, P=0.009) and no correlation between DCT IOP and CCT (r(2)=0.007, slope=0.005 mm Hg/microm, P=0.468). In glaucomatous eyes, there was no correlation between GAT IOP and CCT (r(2)=0.006, slope=0.007 mm Hg/microm, P=0.473) and a weak inverse correlation between DCT IOP and CCT (r(2)=0.075, slope=-0.021 mm Hg/microm, P=0.008). CONCLUSIONS: Both GAT and DCT are affected by CCT, albeit in different ways. Normal and glaucomatous eyes exhibit different relationships between CCT and IOP measured by either GAT or DCT. The relationships between CCT and transcorneal IOP measurements are complex and incompletely characterized, which limits the clinical interpretation of GAT and DCT measurements of IOP in both normal and glaucomatous eyes. SN - 1536-481X UR - https://www.unboundmedicine.com/medline/citation/19225347/Correlation_of_intraocular_pressure_measured_with_goldmann_and_dynamic_contour_tonometry_in_normal_and_glaucomatous_eyes_ L2 - http://Insights.ovid.com/pubmed?pmid=19225347 DB - PRIME DP - Unbound Medicine ER -