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Social and ethnic differences in folic acid use preconception and during early pregnancy in the UK: effect on maternal folate status.
J Hum Nutr Diet 2009; 22(2):100-7JH

Abstract

BACKGROUND

The role of folate supplementation in preventing neural tube defects is well known; however, preconception supplement use continues to be low, especially amongst the socially disadvantaged. The present study explored periconception folic acid supplement use in a socially deprived, ethnically diverse population.

METHODS

Pregnant women (n = 402) in the first trimester of pregnancy were recruited in East London. Using a researcher led questionnaire, details were obtained regarding social class, ethnicity and folic acid use. Red cell folate levels were determined for 367 participants during the first trimester.

RESULTS

Although 76% of participants reported using folic acid supplements during the first trimester, only 12% started preconception and a further 17% started before neural tube closure. Mothers from higher social groups or with higher levels of education were more likely to use folic acid and started taking it earlier. Ethnic differences were also seen in preconception usage (Africans, 5%; West Indians, 8%; Asians, 12%; Caucasians, 19%; P = 0.038). Participants who took folic acid supplements had significantly higher mean (SD) red cell folate concentrations than those who took none [936 (*\1.6) and 579 (*\1.6) nmol L(-1), respectively; P < 0.001].

CONCLUSIONS

Folic acid supplement use preconception and prior to neural tube closure continues to be low, exhibiting both social and ethnic disparities.

Authors+Show Affiliations

Institute of Food Nutrition and Human Health, Massey University, Palmerston North, New Zealand. l.brough@massey.ac.nzNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19226351

Citation

Brough, L, et al. "Social and Ethnic Differences in Folic Acid Use Preconception and During Early Pregnancy in the UK: Effect On Maternal Folate Status." Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association, vol. 22, no. 2, 2009, pp. 100-7.
Brough L, Rees GA, Crawford MA, et al. Social and ethnic differences in folic acid use preconception and during early pregnancy in the UK: effect on maternal folate status. J Hum Nutr Diet. 2009;22(2):100-7.
Brough, L., Rees, G. A., Crawford, M. A., & Dorman, E. K. (2009). Social and ethnic differences in folic acid use preconception and during early pregnancy in the UK: effect on maternal folate status. Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association, 22(2), pp. 100-7. doi:10.1111/j.1365-277X.2008.00936.x.
Brough L, et al. Social and Ethnic Differences in Folic Acid Use Preconception and During Early Pregnancy in the UK: Effect On Maternal Folate Status. J Hum Nutr Diet. 2009;22(2):100-7. PubMed PMID: 19226351.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Social and ethnic differences in folic acid use preconception and during early pregnancy in the UK: effect on maternal folate status. AU - Brough,L, AU - Rees,G A, AU - Crawford,M A, AU - Dorman,E K, Y1 - 2009/02/13/ PY - 2009/2/20/entrez PY - 2009/2/20/pubmed PY - 2009/7/8/medline SP - 100 EP - 7 JF - Journal of human nutrition and dietetics : the official journal of the British Dietetic Association JO - J Hum Nutr Diet VL - 22 IS - 2 N2 - BACKGROUND: The role of folate supplementation in preventing neural tube defects is well known; however, preconception supplement use continues to be low, especially amongst the socially disadvantaged. The present study explored periconception folic acid supplement use in a socially deprived, ethnically diverse population. METHODS: Pregnant women (n = 402) in the first trimester of pregnancy were recruited in East London. Using a researcher led questionnaire, details were obtained regarding social class, ethnicity and folic acid use. Red cell folate levels were determined for 367 participants during the first trimester. RESULTS: Although 76% of participants reported using folic acid supplements during the first trimester, only 12% started preconception and a further 17% started before neural tube closure. Mothers from higher social groups or with higher levels of education were more likely to use folic acid and started taking it earlier. Ethnic differences were also seen in preconception usage (Africans, 5%; West Indians, 8%; Asians, 12%; Caucasians, 19%; P = 0.038). Participants who took folic acid supplements had significantly higher mean (SD) red cell folate concentrations than those who took none [936 (*\1.6) and 579 (*\1.6) nmol L(-1), respectively; P < 0.001]. CONCLUSIONS: Folic acid supplement use preconception and prior to neural tube closure continues to be low, exhibiting both social and ethnic disparities. SN - 1365-277X UR - https://www.unboundmedicine.com/medline/citation/19226351/Social_and_ethnic_differences_in_folic_acid_use_preconception_and_during_early_pregnancy_in_the_UK:_effect_on_maternal_folate_status_ L2 - https://doi.org/10.1111/j.1365-277X.2008.00936.x DB - PRIME DP - Unbound Medicine ER -