Tags

Type your tag names separated by a space and hit enter

Pieris brassicae inhibits xanthine oxidase.
J Agric Food Chem. 2009 Mar 25; 57(6):2288-94.JA

Abstract

The antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout.

Authors+Show Affiliations

REQUIMTE/Servico de Farmacognosia, Faculdade de Farmacia, Universidade do Porto, Porto, Portugal.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19227975

Citation

Sousa, Carla, et al. "Pieris Brassicae Inhibits Xanthine Oxidase." Journal of Agricultural and Food Chemistry, vol. 57, no. 6, 2009, pp. 2288-94.
Sousa C, Pereira DM, Valentão P, et al. Pieris brassicae inhibits xanthine oxidase. J Agric Food Chem. 2009;57(6):2288-94.
Sousa, C., Pereira, D. M., Valentão, P., Ferreres, F., Pereira, J. A., Seabra, R. M., & Andrade, P. B. (2009). Pieris brassicae inhibits xanthine oxidase. Journal of Agricultural and Food Chemistry, 57(6), 2288-94. https://doi.org/10.1021/jf803831v
Sousa C, et al. Pieris Brassicae Inhibits Xanthine Oxidase. J Agric Food Chem. 2009 Mar 25;57(6):2288-94. PubMed PMID: 19227975.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pieris brassicae inhibits xanthine oxidase. AU - Sousa,Carla, AU - Pereira,David M, AU - Valentão,Patrícia, AU - Ferreres,Federico, AU - Pereira,José A, AU - Seabra,Rosa M, AU - Andrade,Paula B, PY - 2009/2/21/entrez PY - 2009/2/21/pubmed PY - 2009/5/7/medline SP - 2288 EP - 94 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 57 IS - 6 N2 - The antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout. SN - 1520-5118 UR - https://www.unboundmedicine.com/medline/citation/19227975/Pieris_brassicae_inhibits_xanthine_oxidase_ L2 - https://doi.org/10.1021/jf803831v DB - PRIME DP - Unbound Medicine ER -