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Glossitis with linear lesions: an early sign of vitamin B12 deficiency.
J Am Acad Dermatol. 2009 Mar; 60(3):498-500.JA

Abstract

The classic oral manifestations of vitamin B(12) deficiency are considered nonspecific. We describe 4 patients with oral linear lesions associated with vitamin B(12) deficiency. Patients were free of neurologic symptoms and anemia at diagnosis. We believe that glossitis with linear lesions is an early clinical sign of vitamin B(12) deficiency. We recommend the determination of vitamin B(12) in such patients, even in the absence of anemia.

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Authors+Show Affiliations

Graells J
Department of Dermatology, Hospital de Sant Joan de Déu de Sant Boi de Llobregat, Barcelona, Spain. 26449jge@comb.es
Ojeda RM
No affiliation info available
Muniesa C
No affiliation info available
Gonzalez J
No affiliation info available
Saavedra J
No affiliation info available

MeSH

AdultAgedEarly DiagnosisFemaleGlossitisHashimoto DiseaseHumansMaleMelanomaMiddle AgedSkin NeoplasmsStomatitisTongueVitamin B 12 Deficiency

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

19231648

Citation

Graells, Jordi, et al. "Glossitis With Linear Lesions: an Early Sign of Vitamin B12 Deficiency." Journal of the American Academy of Dermatology, vol. 60, no. 3, 2009, pp. 498-500.
Graells J, Ojeda RM, Muniesa C, et al. Glossitis with linear lesions: an early sign of vitamin B12 deficiency. J Am Acad Dermatol. 2009;60(3):498-500.
Graells, J., Ojeda, R. M., Muniesa, C., Gonzalez, J., & Saavedra, J. (2009). Glossitis with linear lesions: an early sign of vitamin B12 deficiency. Journal of the American Academy of Dermatology, 60(3), 498-500. https://doi.org/10.1016/j.jaad.2008.09.011
Graells J, et al. Glossitis With Linear Lesions: an Early Sign of Vitamin B12 Deficiency. J Am Acad Dermatol. 2009;60(3):498-500. PubMed PMID: 19231648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Glossitis with linear lesions: an early sign of vitamin B12 deficiency. AU - Graells,Jordi, AU - Ojeda,Rosa Maria, AU - Muniesa,Cristina, AU - Gonzalez,Jesus, AU - Saavedra,Jose, PY - 2008/07/06/received PY - 2008/08/29/revised PY - 2008/09/02/accepted PY - 2009/2/24/entrez PY - 2009/2/24/pubmed PY - 2009/3/24/medline SP - 498 EP - 500 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 60 IS - 3 N2 - The classic oral manifestations of vitamin B(12) deficiency are considered nonspecific. We describe 4 patients with oral linear lesions associated with vitamin B(12) deficiency. Patients were free of neurologic symptoms and anemia at diagnosis. We believe that glossitis with linear lesions is an early clinical sign of vitamin B(12) deficiency. We recommend the determination of vitamin B(12) in such patients, even in the absence of anemia. SN - 1097-6787 UR - https://www.unboundmedicine.com/medline/citation/19231648/Glossitis_with_linear_lesions:_an_early_sign_of_vitamin_B12_deficiency_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0190-9622(08)01149-3 DB - PRIME DP - Unbound Medicine ER -