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The significance of patent foramen ovale: a current review of associated conditions and treatment.
Int J Cardiol 2009; 134(1):17-24IJ

Abstract

Patent foramen ovale (PFO) is a remnant of the foetal circulation, found in about a quarter of the population. PFO is an asymptomatic condition and the high prevalence infers that it is in most cases of no or only limited clinical significance. However, recent research has found an increased prevalence of PFO in cryptogenic stroke, decompression illness and migraine. The presence of a PFO has also been associated with oxygen desaturation in conditions such as obstructive pulmonary disease and obstructive sleep apnoea. The rapid evolution and widespread availability of catheter-based closing techniques have further stimulated interest. The seemingly growing significance of PFO will be discussed in this review.

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    Authors+Show Affiliations

    Johansson MC
    Department of Emergency and Cardiovascular Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Magnus.C.Johansson@vgregion.se
    Eriksson P
    No affiliation info available
    Dellborg M
    No affiliation info available

    MeSH

    Foramen Ovale, PatentHumansMigraine DisordersPrevalenceSleep Apnea SyndromesStroke

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    19232760

    Citation

    Johansson, Magnus C., et al. "The Significance of Patent Foramen Ovale: a Current Review of Associated Conditions and Treatment." International Journal of Cardiology, vol. 134, no. 1, 2009, pp. 17-24.
    Johansson MC, Eriksson P, Dellborg M. The significance of patent foramen ovale: a current review of associated conditions and treatment. Int J Cardiol. 2009;134(1):17-24.
    Johansson, M. C., Eriksson, P., & Dellborg, M. (2009). The significance of patent foramen ovale: a current review of associated conditions and treatment. International Journal of Cardiology, 134(1), pp. 17-24. doi:10.1016/j.ijcard.2009.01.049.
    Johansson MC, Eriksson P, Dellborg M. The Significance of Patent Foramen Ovale: a Current Review of Associated Conditions and Treatment. Int J Cardiol. 2009 May 1;134(1):17-24. PubMed PMID: 19232760.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The significance of patent foramen ovale: a current review of associated conditions and treatment. AU - Johansson,Magnus C, AU - Eriksson,Peter, AU - Dellborg,Mikael, Y1 - 2009/02/20/ PY - 2008/10/20/received PY - 2009/01/10/accepted PY - 2009/2/24/entrez PY - 2009/2/24/pubmed PY - 2009/7/17/medline SP - 17 EP - 24 JF - International journal of cardiology JO - Int. J. Cardiol. VL - 134 IS - 1 N2 - Patent foramen ovale (PFO) is a remnant of the foetal circulation, found in about a quarter of the population. PFO is an asymptomatic condition and the high prevalence infers that it is in most cases of no or only limited clinical significance. However, recent research has found an increased prevalence of PFO in cryptogenic stroke, decompression illness and migraine. The presence of a PFO has also been associated with oxygen desaturation in conditions such as obstructive pulmonary disease and obstructive sleep apnoea. The rapid evolution and widespread availability of catheter-based closing techniques have further stimulated interest. The seemingly growing significance of PFO will be discussed in this review. SN - 1874-1754 UR - https://www.unboundmedicine.com/medline/citation/19232760/The_significance_of_patent_foramen_ovale:_a_current_review_of_associated_conditions_and_treatment_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-5273(09)00101-6 DB - PRIME DP - Unbound Medicine ER -