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The significance of patent foramen ovale: a current review of associated conditions and treatment.
Int J Cardiol. 2009 May 01; 134(1):17-24.IJ

Abstract

Patent foramen ovale (PFO) is a remnant of the foetal circulation, found in about a quarter of the population. PFO is an asymptomatic condition and the high prevalence infers that it is in most cases of no or only limited clinical significance. However, recent research has found an increased prevalence of PFO in cryptogenic stroke, decompression illness and migraine. The presence of a PFO has also been associated with oxygen desaturation in conditions such as obstructive pulmonary disease and obstructive sleep apnoea. The rapid evolution and widespread availability of catheter-based closing techniques have further stimulated interest. The seemingly growing significance of PFO will be discussed in this review.

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Authors+Show Affiliations

Johansson MC
Department of Emergency and Cardiovascular Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Magnus.C.Johansson@vgregion.se
Eriksson P
No affiliation info available
Dellborg M
No affiliation info available

MeSH

Foramen Ovale, PatentHumansMigraine DisordersPrevalenceSleep Apnea SyndromesStroke

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

19232760

Citation

Johansson, Magnus C., et al. "The Significance of Patent Foramen Ovale: a Current Review of Associated Conditions and Treatment." International Journal of Cardiology, vol. 134, no. 1, 2009, pp. 17-24.
Johansson MC, Eriksson P, Dellborg M. The significance of patent foramen ovale: a current review of associated conditions and treatment. Int J Cardiol. 2009;134(1):17-24.
Johansson, M. C., Eriksson, P., & Dellborg, M. (2009). The significance of patent foramen ovale: a current review of associated conditions and treatment. International Journal of Cardiology, 134(1), 17-24. https://doi.org/10.1016/j.ijcard.2009.01.049
Johansson MC, Eriksson P, Dellborg M. The Significance of Patent Foramen Ovale: a Current Review of Associated Conditions and Treatment. Int J Cardiol. 2009 May 1;134(1):17-24. PubMed PMID: 19232760.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The significance of patent foramen ovale: a current review of associated conditions and treatment. AU - Johansson,Magnus C, AU - Eriksson,Peter, AU - Dellborg,Mikael, Y1 - 2009/02/20/ PY - 2008/10/20/received PY - 2009/01/10/accepted PY - 2009/2/24/entrez PY - 2009/2/24/pubmed PY - 2009/7/17/medline SP - 17 EP - 24 JF - International journal of cardiology JO - Int J Cardiol VL - 134 IS - 1 N2 - Patent foramen ovale (PFO) is a remnant of the foetal circulation, found in about a quarter of the population. PFO is an asymptomatic condition and the high prevalence infers that it is in most cases of no or only limited clinical significance. However, recent research has found an increased prevalence of PFO in cryptogenic stroke, decompression illness and migraine. The presence of a PFO has also been associated with oxygen desaturation in conditions such as obstructive pulmonary disease and obstructive sleep apnoea. The rapid evolution and widespread availability of catheter-based closing techniques have further stimulated interest. The seemingly growing significance of PFO will be discussed in this review. SN - 1874-1754 UR - https://www.unboundmedicine.com/medline/citation/19232760/The_significance_of_patent_foramen_ovale:_a_current_review_of_associated_conditions_and_treatment_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-5273(09)00101-6 DB - PRIME DP - Unbound Medicine ER -