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Antimicrobial activity of Drosophyllum lusitanicum, an endemic Mediterranean insectivorous plant.
Nat Prod Res. 2009; 23(3):219-29.NP

Abstract

The aim of this study was to evaluate the antimicrobial activity of Drosophyllum lusitanicum leaf extract against various yeasts and bacteria species, including both standard and clinically isolated strains. The extract exhibited strong antimicrobial activity against all the tested yeast strains with inhibition zones ranging 23.67-42.23 mm and with minimum inhibitory concentration (MIC) values ranging 31-63 microg L(-1). All the Gram-positive bacteria studied were inhibited by the extract, showing inhibition zones ranging 17.67-43.00 mm and MIC values comprising between 15.6 and 250 microg L(-1). In contrast, the growth of the tested Gram-negative bacteria was not significantly affected by the extract. Among the microorganisms tested, Staphylococcus epidermidis ATCC 12228 was the most sensitive, presenting the lowest MIC value (15.6 microg L(-1)), while Enterococcus faecalis ATCC 29212 was the most tolerant (250 microg L(-1)). The extract of D. lusitanicum was analysed by gas chromatography-mass spectrometry and the major constituent found was plumbagin.

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Authors+Show Affiliations

Gonçalves S
Institute for Biotechnology and Bioengineering, Centre for Molecular and Structural Biomedicine, University of Algarve, Faro, Portugal.
Quintas C
No affiliation info available
Gaspar MN
No affiliation info available
Nogueira JM
No affiliation info available
Romano A
No affiliation info available

MeSH

Anti-Infective AgentsGas Chromatography-Mass SpectrometryGram-Negative BacteriaGram-Positive BacteriaMagnoliopsidaMicrobial Sensitivity TestsNaphthoquinonesPlant ExtractsPlant LeavesYeasts

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19235022

Citation

Gonçalves, Sandra, et al. "Antimicrobial Activity of Drosophyllum Lusitanicum, an Endemic Mediterranean Insectivorous Plant." Natural Product Research, vol. 23, no. 3, 2009, pp. 219-29.
Gonçalves S, Quintas C, Gaspar MN, et al. Antimicrobial activity of Drosophyllum lusitanicum, an endemic Mediterranean insectivorous plant. Nat Prod Res. 2009;23(3):219-29.
Gonçalves, S., Quintas, C., Gaspar, M. N., Nogueira, J. M., & Romano, A. (2009). Antimicrobial activity of Drosophyllum lusitanicum, an endemic Mediterranean insectivorous plant. Natural Product Research, 23(3), 219-29. https://doi.org/10.1080/14786410801972870
Gonçalves S, et al. Antimicrobial Activity of Drosophyllum Lusitanicum, an Endemic Mediterranean Insectivorous Plant. Nat Prod Res. 2009;23(3):219-29. PubMed PMID: 19235022.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial activity of Drosophyllum lusitanicum, an endemic Mediterranean insectivorous plant. AU - Gonçalves,Sandra, AU - Quintas,Célia, AU - Gaspar,Maria N, AU - Nogueira,José M F, AU - Romano,Anabela, PY - 2009/2/24/entrez PY - 2009/2/24/pubmed PY - 2009/4/7/medline SP - 219 EP - 29 JF - Natural product research JO - Nat Prod Res VL - 23 IS - 3 N2 - The aim of this study was to evaluate the antimicrobial activity of Drosophyllum lusitanicum leaf extract against various yeasts and bacteria species, including both standard and clinically isolated strains. The extract exhibited strong antimicrobial activity against all the tested yeast strains with inhibition zones ranging 23.67-42.23 mm and with minimum inhibitory concentration (MIC) values ranging 31-63 microg L(-1). All the Gram-positive bacteria studied were inhibited by the extract, showing inhibition zones ranging 17.67-43.00 mm and MIC values comprising between 15.6 and 250 microg L(-1). In contrast, the growth of the tested Gram-negative bacteria was not significantly affected by the extract. Among the microorganisms tested, Staphylococcus epidermidis ATCC 12228 was the most sensitive, presenting the lowest MIC value (15.6 microg L(-1)), while Enterococcus faecalis ATCC 29212 was the most tolerant (250 microg L(-1)). The extract of D. lusitanicum was analysed by gas chromatography-mass spectrometry and the major constituent found was plumbagin. SN - 1478-6427 UR - https://www.unboundmedicine.com/medline/citation/19235022/Antimicrobial_activity_of_Drosophyllum_lusitanicum_an_endemic_Mediterranean_insectivorous_plant_ L2 - https://www.tandfonline.com/doi/full/10.1080/14786410801972870 DB - PRIME DP - Unbound Medicine ER -