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Administration of dietary fish oil capsules in healthy middle-aged Japanese men with a high level of fish consumption.
Int J Food Sci Nutr. 2009; 60 Suppl 5:136-42.IJ

Abstract

The nutritional effects of fish oil, which is rich in the n-3 polyunsaturated fatty acids, have been reported. In this randomized, placebo-controlled, double-blind, crossover study, we evaluated the effects of dietary fish oil capsules on the hematological parameters of healthy middle-aged Japanese men with a high level of fish oil consumption. Over a 4-week period, subjects were administered five fish oil or olive oil (placebo) capsules with every meal (1,260 mg eicosapentaenoic acid and 540 mg docosahexaenoic acid/day). There was a 4-week washout period between the treatment phases. The results did not demonstrate a decrease in plasma triacylglycerol, cholesterol, low-density lipoprotein cholesterol, and whole-blood viscosity. Further, no changes in the fatty acid composition of plasma and erythrocyte phospholipids were noted. These results suggested that the supplementation of fish oil might be effective only for those subjects who have a lower level of fish oil consumption.

Authors+Show Affiliations

Department of Food Science and Nutrition, Faculty of Human Ecology, Showa Women's University, 1-7-57 Taishido, Setagaya, Tokyo, Japan. nakamich@swu.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

19255890

Citation

Watanabe, N, et al. "Administration of Dietary Fish Oil Capsules in Healthy Middle-aged Japanese Men With a High Level of Fish Consumption." International Journal of Food Sciences and Nutrition, vol. 60 Suppl 5, 2009, pp. 136-42.
Watanabe N, Watanabe Y, Kumagai M, et al. Administration of dietary fish oil capsules in healthy middle-aged Japanese men with a high level of fish consumption. Int J Food Sci Nutr. 2009;60 Suppl 5:136-42.
Watanabe, N., Watanabe, Y., Kumagai, M., & Fujimoto, K. (2009). Administration of dietary fish oil capsules in healthy middle-aged Japanese men with a high level of fish consumption. International Journal of Food Sciences and Nutrition, 60 Suppl 5, 136-42. https://doi.org/10.1080/09637480802683942
Watanabe N, et al. Administration of Dietary Fish Oil Capsules in Healthy Middle-aged Japanese Men With a High Level of Fish Consumption. Int J Food Sci Nutr. 2009;60 Suppl 5:136-42. PubMed PMID: 19255890.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Administration of dietary fish oil capsules in healthy middle-aged Japanese men with a high level of fish consumption. AU - Watanabe,N, AU - Watanabe,Y, AU - Kumagai,M, AU - Fujimoto,K, Y1 - 2009/02/28/ PY - 2009/3/4/entrez PY - 2009/3/4/pubmed PY - 2010/7/2/medline SP - 136 EP - 42 JF - International journal of food sciences and nutrition JO - Int J Food Sci Nutr VL - 60 Suppl 5 N2 - The nutritional effects of fish oil, which is rich in the n-3 polyunsaturated fatty acids, have been reported. In this randomized, placebo-controlled, double-blind, crossover study, we evaluated the effects of dietary fish oil capsules on the hematological parameters of healthy middle-aged Japanese men with a high level of fish oil consumption. Over a 4-week period, subjects were administered five fish oil or olive oil (placebo) capsules with every meal (1,260 mg eicosapentaenoic acid and 540 mg docosahexaenoic acid/day). There was a 4-week washout period between the treatment phases. The results did not demonstrate a decrease in plasma triacylglycerol, cholesterol, low-density lipoprotein cholesterol, and whole-blood viscosity. Further, no changes in the fatty acid composition of plasma and erythrocyte phospholipids were noted. These results suggested that the supplementation of fish oil might be effective only for those subjects who have a lower level of fish oil consumption. SN - 1465-3478 UR - https://www.unboundmedicine.com/medline/citation/19255890/Administration_of_dietary_fish_oil_capsules_in_healthy_middle_aged_Japanese_men_with_a_high_level_of_fish_consumption_ L2 - https://www.tandfonline.com/doi/full/10.1080/09637480802683942 DB - PRIME DP - Unbound Medicine ER -