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Role of endocannabinoids in cardiovascular shock.
J Physiol Pharmacol. 2008 Dec; 59 Suppl 8:91-107.JP

Abstract

Endocannabinoids (e.g. anandamide, 2-arachidonoylglycerol or virodhamine) regulate the function of the cardiovascular system mainly in the following way: 1) by acting via CB(1) receptors, 2) by activation of CB(2) receptors, and 3) by modifying the function of vanilloid TRPV1, serotonin 5-HT(3) and alpha(7)-subunit-containing nicotinic acetylcholine receptors. Endocannabinoids are implicated in the pathogenesis of hypertension and of hypotension associated with haemorrhagic, endotoxic, and cardiogenic shock, and with advanced liver cirrhosis. There is also evidence for their involvement in the control of atherosclerosis.

Authors+Show Affiliations

Department of Experimental Physiology, Medical University of Bialystok, Bialystok, Poland. bmalin@umwb.edu.plNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

19258666

Citation

Malinowska, B, et al. "Role of Endocannabinoids in Cardiovascular Shock." Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society, vol. 59 Suppl 8, 2008, pp. 91-107.
Malinowska B, Lupinski S, Godlewski G, et al. Role of endocannabinoids in cardiovascular shock. J Physiol Pharmacol. 2008;59 Suppl 8:91-107.
Malinowska, B., Lupinski, S., Godlewski, G., Baranowska, U., & Schlicker, E. (2008). Role of endocannabinoids in cardiovascular shock. Journal of Physiology and Pharmacology : an Official Journal of the Polish Physiological Society, 59 Suppl 8, 91-107.
Malinowska B, et al. Role of Endocannabinoids in Cardiovascular Shock. J Physiol Pharmacol. 2008;59 Suppl 8:91-107. PubMed PMID: 19258666.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Role of endocannabinoids in cardiovascular shock. AU - Malinowska,B, AU - Lupinski,S, AU - Godlewski,G, AU - Baranowska,U, AU - Schlicker,E, PY - 2008/10/24/received PY - 2008/11/28/accepted PY - 2009/3/5/entrez PY - 2009/3/11/pubmed PY - 2009/4/7/medline SP - 91 EP - 107 JF - Journal of physiology and pharmacology : an official journal of the Polish Physiological Society JO - J. Physiol. Pharmacol. VL - 59 Suppl 8 N2 - Endocannabinoids (e.g. anandamide, 2-arachidonoylglycerol or virodhamine) regulate the function of the cardiovascular system mainly in the following way: 1) by acting via CB(1) receptors, 2) by activation of CB(2) receptors, and 3) by modifying the function of vanilloid TRPV1, serotonin 5-HT(3) and alpha(7)-subunit-containing nicotinic acetylcholine receptors. Endocannabinoids are implicated in the pathogenesis of hypertension and of hypotension associated with haemorrhagic, endotoxic, and cardiogenic shock, and with advanced liver cirrhosis. There is also evidence for their involvement in the control of atherosclerosis. SN - 1899-1505 UR - https://www.unboundmedicine.com/medline/citation/19258666/Role_of_endocannabinoids_in_cardiovascular_shock_ DB - PRIME DP - Unbound Medicine ER -