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Coffee consumption and risk of cardiovascular events and all-cause mortality among women with type 2 diabetes.
Diabetologia 2009; 52(5):810-7D

Abstract

AIMS/HYPOTHESIS

Coffee has been linked to both beneficial and harmful health effects, but data on its relationship with cardiovascular disease and mortality in patients with type 2 diabetes are sparse.

METHODS

This was a prospective cohort study including 7,170 women with diagnosed type 2 diabetes but free of cardiovascular disease or cancer at baseline. Coffee consumption was assessed in 1980 and then every 2-4 years using validated questionnaires. A total of 658 incident cardiovascular events (434 coronary heart disease and 224 stroke) and 734 deaths from all causes were documented between 1980 and 2004.

RESULTS

After adjustment for age, smoking and other cardiovascular risk factors, the relative risks were 0.76 (95% CI 0.50-1.14) for cardiovascular diseases (p trend = 0.09) and 0.80 (95% CI 0.55-1.14) for all-cause mortality (p trend = 0.05) for the consumption of >or=4 cups/day of caffeinated coffee compared with non-drinkers. Similarly, multivariable RRs were 0.96 (95% CI 0.66-1.38) for cardiovascular diseases (p trend = 0.84) and 0.76 (95% CI 0.54-1.07) for all-cause mortality (p trend = 0.08) for the consumption of >or=2 cups/day of decaffeinated coffee compared with non-drinkers. Higher decaffeinated coffee consumption was associated with lower concentrations of HbA(1c) (6.2% for >or=2 cups/day versus 6.7% for <1 cup/month; p trend = 0.02).

CONCLUSIONS

These data provide evidence that habitual coffee consumption is not associated with increased risk of cardiovascular diseases or premature mortality among diabetic women.

Authors+Show Affiliations

Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA. weilizhang@sglab.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19266179

Citation

Zhang, W L., et al. "Coffee Consumption and Risk of Cardiovascular Events and All-cause Mortality Among Women With Type 2 Diabetes." Diabetologia, vol. 52, no. 5, 2009, pp. 810-7.
Zhang WL, Lopez-Garcia E, Li TY, et al. Coffee consumption and risk of cardiovascular events and all-cause mortality among women with type 2 diabetes. Diabetologia. 2009;52(5):810-7.
Zhang, W. L., Lopez-Garcia, E., Li, T. Y., Hu, F. B., & van Dam, R. M. (2009). Coffee consumption and risk of cardiovascular events and all-cause mortality among women with type 2 diabetes. Diabetologia, 52(5), pp. 810-7. doi:10.1007/s00125-009-1311-1.
Zhang WL, et al. Coffee Consumption and Risk of Cardiovascular Events and All-cause Mortality Among Women With Type 2 Diabetes. Diabetologia. 2009;52(5):810-7. PubMed PMID: 19266179.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coffee consumption and risk of cardiovascular events and all-cause mortality among women with type 2 diabetes. AU - Zhang,W L, AU - Lopez-Garcia,E, AU - Li,T Y, AU - Hu,F B, AU - van Dam,R M, Y1 - 2009/03/06/ PY - 2008/11/21/received PY - 2009/02/09/accepted PY - 2009/3/7/entrez PY - 2009/3/7/pubmed PY - 2009/7/30/medline SP - 810 EP - 7 JF - Diabetologia JO - Diabetologia VL - 52 IS - 5 N2 - AIMS/HYPOTHESIS: Coffee has been linked to both beneficial and harmful health effects, but data on its relationship with cardiovascular disease and mortality in patients with type 2 diabetes are sparse. METHODS: This was a prospective cohort study including 7,170 women with diagnosed type 2 diabetes but free of cardiovascular disease or cancer at baseline. Coffee consumption was assessed in 1980 and then every 2-4 years using validated questionnaires. A total of 658 incident cardiovascular events (434 coronary heart disease and 224 stroke) and 734 deaths from all causes were documented between 1980 and 2004. RESULTS: After adjustment for age, smoking and other cardiovascular risk factors, the relative risks were 0.76 (95% CI 0.50-1.14) for cardiovascular diseases (p trend = 0.09) and 0.80 (95% CI 0.55-1.14) for all-cause mortality (p trend = 0.05) for the consumption of >or=4 cups/day of caffeinated coffee compared with non-drinkers. Similarly, multivariable RRs were 0.96 (95% CI 0.66-1.38) for cardiovascular diseases (p trend = 0.84) and 0.76 (95% CI 0.54-1.07) for all-cause mortality (p trend = 0.08) for the consumption of >or=2 cups/day of decaffeinated coffee compared with non-drinkers. Higher decaffeinated coffee consumption was associated with lower concentrations of HbA(1c) (6.2% for >or=2 cups/day versus 6.7% for <1 cup/month; p trend = 0.02). CONCLUSIONS: These data provide evidence that habitual coffee consumption is not associated with increased risk of cardiovascular diseases or premature mortality among diabetic women. SN - 1432-0428 UR - https://www.unboundmedicine.com/medline/citation/19266179/Coffee_consumption_and_risk_of_cardiovascular_events_and_all_cause_mortality_among_women_with_type_2_diabetes_ L2 - https://dx.doi.org/10.1007/s00125-009-1311-1 DB - PRIME DP - Unbound Medicine ER -